Neurological manifestations of anti-phospholipid (Hughes) syndrome

Clinical and Experimental Rheumatology

Volumn 22, Issue 6, 2004, Pages 771-775

  Antunes, Marisa C ^a,b   D'Cruz, David ^a   Hughes, Graham R V ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b Curry Cabral's Hospital   (Portugal)

Author keywords

Anticardiolipin antibodies; Antiphospholipid syndrome; Hypercoagulability; Lupus anticoagulant; Thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; WARFARIN;

ANTIPHOSPHOLIPID SYNDROME; BRAIN PSEUDOTUMOR; CEREBROVASCULAR DISEASE; CHOREA; CLINICAL FEATURE; COGNITIVE DEFECT; DISEASE ASSOCIATION; HUMAN; MIGRAINE; MONONEUROPATHY MULTIPLEX; MOTOR DYSFUNCTION; MULTIINFARCT DEMENTIA; MYELITIS; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; REVIEW; SEIZURE; STROKE; TRANSIENT ISCHEMIC ATTACK; TRANSITIONAL BLINDNESS;

ANTIPHOSPHOLIPID SYNDROME; HUMANS; NERVOUS SYSTEM DISEASES; THROMBOSIS;

EID: 11044220952     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (54)

1. HUGHES GRV: Thrombosis, abortion, thrombosis and the lupus anticoagulant. BMJ 1983; 287: 1088-9.
2. CASTELLINO G, KHAMASHTA MA, HUGHES GRV: Review article - The antiphospholipid syndrome. Eur J Int Med 1999; 10: 191-7.
3. HUGHES GRV: Migraine, memory loss, and "multiple sclerosis". Neurological features of the antiphospholipid (Hughes') syndrome. Postgrad Med J 2003; 79: 81-3.
4. CUADRADO MJ, HUGHES GRV: Hughes (antiphospholipid) syndrome - clinical features. Rheum Dis Clin 2001; 27: 509-24.
5. HESS DC, SHEPARD JC, ADAMS RJ: Increased immunoglobulin binding to cerebral endothelium in patients with APS. Stroke 1993; 24: 994-9.
6. CUADRADO MJ, KHAMASHTA MA, BALLESTEROS A, GODFREY T, SIMON MJ, HUGHES GRV: Can neurological manifestations of Hughes (antiphospholipid) syndrome be distinguished from multiple sclerosis ? Analysis of 27 patients and review of the literature. Medicine (Baltimore) 2000; 79: 57-68.
7. SANNA G, BERTOLACCINI ML, CUADRADO MJ, KHAMASHTA MA, HUGHES GRV: Central nervous system involvement in the antiphospholipid (Hughes) syndrome. Rheumatology 2003; 42: 200-13.
8. SHAH NM, KHAMASHTA MA, ATSUMI T, HUGHES GRV: Outcome of patients with anticardiolipin antibodies: a 10-year follow-up of 52 patients. Lupus 1998; 7: 3-6.
9. HARRIS EN, GHARAVI A, ASHERSON RA, BOEY ML, HUGHES GRV: Cerebral infarction in systemic lupus. Association with anticardiolipin antibodies. Clin Exp Rheumatol 1984; 2: 47-51.
10. KHAMASHTA MA, CERVERA R, ASHERSON RA et al.: Association of antibodies against phospholipids with heart valve disease in systemic lupus erythmatosus. Lancet 1990; 335: 350-3.
11. NESHER G, ILANY J, ROSENMANN D, ABRAHAM AS: Valvular dysfunction in phospholipid syndrome: prevalence, clinical features, and treatment. Semin Arthritis Rheum 1997; 27: 27-35.
12. MACKWORTH-YOUNG CG, HUGHES GRV: Epilepsy: An early symptom of systemic lupus erythematosus. 1985; 48: 185.
13. VERROT D, SAN-MARCO M, DRAVET C et al.: Prevalence and signification of antinuclear and anticardiolipin antibodies in patients with epilepsy. Am J Med 1997; 103: 33-7.
14. PELTOLA JT, HAAPALA A, ISOJARVI JI et al.: Antiphospholipid and antinuclear antibodies in patients with epilepsy or new-onset seizure disorders. Am J Med 2000; 109: 712-7.
15. LEVINE SR, DEEGAN MJ, FUTRELL N, WELCH KM: Cerebrovascular and neurologic disease associated with antiphospholipid antibodies: 48 cases. Neurology 1990; 40: 1181-9.
16. KENT MN, ALVAREZ FJ, ROTE NS: Ultrastructural localization of monoclonal antiphospholipid antibody binding to rat brain. Exp Neurol 2000; 163: 173-9.
17. LIOU HH, WANG CR, CHOU HC et al.: Anticardiolipin antisera from lupus patients with seizures reduce a GABA receptor-mediated chloride current in snail neurons. Life Sci 1994; 54: 1119-25.
18. CUADRADO MJ, KHAMASHTA MA, HUGHES GRV: Sticky blood and headache. Lupus 2001; 10: 392-3.
19. HOGAN MJ, BRUNET DJ, FORD PM: Lupus anticoagulant, antiphospholipid antibodies and migraine. Can J Neurol Sci 1988; 15: 420-5.
20. SANNA G, CUADRADO MJ, NURCHIS P, KHAMASHTA MA, MATHIEU A, HUGHES GRV: Prevalence of headache and relationship with the presence of antiphospholipid antibodies in patients with systemic lupus erythematosus. J Autoimmun 2000; 15: P177 (A75).
21. MONTALBAN J, CERVERA R, FONT J et al.: Lack of association between anticardiolipin antibodies and migraine in systemic lupus reythematosus. Neurology 1992; 42: 681-2.
22. CUADRADO MJ, KHAMASHTA MA, D'CRUZ D, HUGHES GRV: Migraine in Hughes syndrome - heparin as a therapeutic trial ? Q J Med 2001; 94: 114-5.
23. HANLY JG, HONG C, SMITH S et al.: A prospective analysis of cognitive function and anticardiolipin antibodies in systemic lupus erythematosus. Arthritis Rheum 1999; 42: 728-34.
24. MENON S, JAMESON-SHORTALL F, NEWMAN SP, HALL-CRAGGS MR, CHINN R, ISENBERG DA: A longitudinal study of cardiolipin antibody levels and cognitive functioning in systemic lupus erythematosus. Arthritis Rheum 1999; 42: 735-41.
25. POSTIGLIONE A, De CHIARA S, SORICELLI A et al.: Alterations of cerebral blood flow and antiphospholipid antibodies in patients with systemic lupus erythematosus. Int J Clin Lab Res 1998; 28: 34-8.
26. CHAPMAN J, COHEN-ARMON M, SHOENFELD Y, KORCZYN AD: Antiphospholipid antibodies permeabilize and depolarize brain synaptoneurosomes. Lupus 1999; 8: 127-33.
27. MONTALBAN J, FERNANDEZ J, ARDERIU A et al.: Multi-infarct dementia associated with antiphospholipid antibodies. Presentation of two cases. Med Clin (Barc) 1989; 93: 424-6.
28. KURITA A, HASUNUMA T, MOSCHIO S, SHIMADA T, ISOGAI Y, KURAHASHI T: A young case with multi-infarct dementia associated with lupus anticoagulant. Intern Med 1994. 33: 373-5.
29. WESTERMAN EM, MILES JM, BACKONJA M, SUNDSTROM WR: Neuropathologic findings in multi-infarct dementia associated with anticardiolipin antibody. Evidence for endothelial injury as the primary event. Arthritis Rheum 1992; 35: 1038-41.
30. HILKER R, THIEL A, GEISEN C, RUDOLF J: Cerebral blood flow and glucose metabolism in multi-infarct-demencia related to primary antiphospholipid syndrome. Lupus 2000; 9: 311-6.
31. ASHERSON RA, HUGHES GRV: Antiphospholipid antibodies and chorea. J Rheumatol 1998; 15: 377-9.
32. SUNDEN-CULLBERG J, TEDROFF J, AQUILONIUS S: Reversible chorea in primary antiphospholipid syndrome. Movement Dis 1998; 13: 147-9.
33. CUADRADO MJ, WAKEFIELD K, SANNA G, KHAMASHTA MA, HUGHES GRV: Multiple sclerosis and the antiphospholipid (Hughes) syndrome: a common differential diagnosis ? Clin Exp Rheumatol 2004; 22: 652-3.
34. KARUSSIS V, LEKER RR ASHKENAZI A, ABRAMSKY O: A subgroup of multiple sclerosis patients with anticardiolipin antibodies and unusual clinical manifestations: do they represent a new nosological entity ? Ann Neurol 1998; 44: 629-34.
35. ALARCON-SEGOVIA D, DELEZE M, ORIA CV et al.: Antiphospholipid antibodies and the antiphospholipid syndrome in systemic lupus erythematosus. A prospective analysis of 500 consecutive patients. Medicine (Baltimore) 1998; 68: 563-5.
36. RUIZ-ARGUELLES GJ, GUZMAN-RAMOS J, FLORES-FLORES J, GARAY-MARTINEZ J: Refractory hiccough heralding tranverse myelitis in the primary antiphospholipid syndrome. Lupus 1998; 7: 49-50.
37. KOVACS B, LAFFERTY TL, BRENT LH, De HORATIUS RJ: Transverse myelopathy in systemic lupus erythematosus: an analysis of 14 cases and review of the literature. Ann Rheum Dis 2000. 59: 120-4.
38. BLANK M, KRAUSE I, SHOENFELD Y: The contribution of experimental models to our understanding of etiology, pathogenesis and novel therapies in the antiphospholipid syndrome. In KHAMASHTA MA (Ed.): Hughes Syndrome: Antiphospholipid Syndrome. London, Springer-Verlag 2000; 379-90.
39. OREFICE G, De JOANNA G, COPPOLA M, BRANCACCIO V, AMES PR: Benign intracranial hypertension: A non-thrombotic complication of primary antiphospholipid syndrome? Lupus 1995; 4: 324-6.
40. SUSSMAN J, LEACH M, GREAVES M, MALIA R, DAVIES-JONES GA: Potentially prothrombotic abnormalities of coagulation in benign intracranial hypertension. J Neurol Neurosurg Psychiatry 1997; 62: 229-33.
41. HISASHI K, KOMUNE S, TAIRA T, UEMURA T, SADOSHIMA S, TSUDA H: Anticardiolipin antibody-induced sudden profound sensorineural hearing loss. Am J Otolaryngol 1993; 14: 275-7.
42. CASOLI P, TUMIATI B: Cogan's syndrome: a new possible complication of antiphospholipid antibodies ? Clin Rheumatol 1995; 14: 197-8.
43. TUMIATI B, CASOLI P: Sudden sensorineural hearing loss and anticardiolipin antibody. Am J Otolaryngol 1995; 16: 220.
44. GILBURD B, STEIN M, TOMER Y et al.: Antoantibodies to phospholipids and brain extract in patients with the Guillain-Barré syndrome: cross-reactive or pathogenic ? Autoimmunity 1993; 16: 23-7.
45. WIECHENS B, SCHRODER JO, POTZSCH B, ROCHELS R: Primary antiphospholipid antibody syndrome and retinal occlusive vasculopathy. Am J Ophthalmol 1997; 123: 848-50.
46. KLEINER RC, NAJARIAN LV, SCATTEN S et al.: Vaso-occlusive retinopathy associated with antiphospholipid antibodies (lupus anticoagulant retinopathy). Ophthalmology 1989; 96: 896-904.
47. GIORG D, BALACCO G, GABRIELI CB: Optic neuropathy in systemic lupus erythematosus and antiphospholipid syndrome (APS): Clinical features, pathogenesis, review of the literature and proposed opthalmological criteria for APS diagnosis. Clin Rheumatol 1999; 18: 124-31.
48. MONTALBAN J, ARBOIX A, STAUB H et al.: Transient global amnesia and antiphospholipid syndrome. Clin Exp Rheumatol 1989; 7: 85-7.
49. MILANOV I, BOGDANOVA D: Antiphospholipid syndrome and dystonia-parkinsonism. A case report. Parkinsonism Relat Disord 2001; 7: 139-41.
50. SHAH MN, KHAMASHTA MA, ATSUMI T et al.: Outcome of patients with anticardiolipin antibodies: a ten-year follow-up of 52 patients. Lupus 1998; 7: 3-6.
51. KHAMASHTA MA, CUADRADO MJ, MUJIC F, TAUB NA, HUNT BJ, HUGHES GRV: The management of thrombosis in the antiphospholipid-antibody syndrome. N Engl J Med 1995; 332: 993-7.
52. SAOUR JN, SIECK JO, MAMO LAR, GALLUS AS: Trial of different intensities of anticoagulation in patients with prosthetic heart valves. N Engl J Med 1990; 332: 428-32.
53. HIRSH J, FUSTER V: Guide to anticoagulant therapy. Part 2. Oral anticoagulants. Circulation 1994; 89: 1469-80.
54. GOMEZ-PACHECO L, VILLA AR, DRENKARD C, CABIEDES J, CABRAL AR, ALARCON-SEGOVIA D: Serum anti-beta2-glycoprotein-I and anticardiolipin antibodies during thrombosis in systemic lupus erythemathosus patients. Am J Med 1999; 106: 417-23.