Corticotropin-releasing factor overexpression decreases ethanol drinking and increases sensitivity to the sedative effects of ethanol

Psychopharmacology

Volumn 176, Issue 3-4, 2004, Pages 386-397

  Palmer, Abraham A ^a,b,c   Sharpe, Amanda L ^a,b   Burkhart Kasch, Sue ^a,b   McKinnon, Carrie S ^a,b   Coste, Sarah C ^d   Stenzel Poore, Mary P ^d   Phillips, Tamara J ^a,b,e  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^c Columbia University ^*  (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

Alcoholism; Corticotropin releasing factor; Drinking; Ethanol; Genetic; Transgenic mice

Indexed keywords

ALCOHOL; CORTICOTROPIN RELEASING FACTOR;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRINKING BEHAVIOR; GENE OVEREXPRESSION; GENOTYPE; HYPNOSIS; LONGITUDINAL STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RIGHTING REFLEX; SEDATION; TASTE AVERSION; TRANSGENE; TRANSGENIC MOUSE;

AGING; ALCOHOL DRINKING; ANIMALS; AVOIDANCE LEARNING; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CORTICOTROPIN-RELEASING HORMONE; ETHANOL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCULOSKELETAL EQUILIBRIUM; QUININE; REFLEX; SACCHARIN; TASTE;

EID: 10944273919     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-004-1896-5     Document Type: Article

References (37)

1. Bell SM, Reynolds JG, Thiele TE, Gan J, Figlewicz DP, Woods SC (1998) Effects of third intracerebroventricular injections of corticotropin-releasing factor (CRF) on ethanol drinking and food intake. Psychopharmacology 139:128-135
2. von Bardeleben U, Heuser I, Holsboer F (1989) Human CRH stimulation response during acute withdrawal and after medium-term abstention from alcohol abuse. Psychoneuroendocrinology 14:441-449
3. Chester JA, Lumeng L, Li TK, Grahame NJ (2003) High- and low-alcohol-preferring mice show differences in conditioned taste aversion to alcohol. Alcohol Clin Exp Res 27:12-18
4. Costa A, Bono G, Martignoni E, Merlo P, Sances G, Nappi G (1996) An assessment of hypothalamo-pituitary-adrenal axis functioning in non-depressed, early abstinent alcoholics. Psychoneuroendocrinology 21:263-275
5. Coste SC, Murray SE, Stenzel-Poore MP (2001) Animal models of CRH excess and CRH receptor deficiency display altered adaptations to stress. Peptides 22:733-741
6. Ehlers CL, Chaplin RI, Wall TL, Lumeng L, Li TK, Owens MJ, Nemeroff CB (1992) Corticotropin releasing factor (CRF): studies in alcohol preferring and non-preferring rats. Psychopharmacology 106:359-364
7. Ehrenreich H, Schuck J, Stender N, Pilz J, Gefeller O, Schilling L, Poser W, Kaw S (1997) Endocrine and hemodynamic effects of stress versus systemic CRF in alcoholics during early and medium term abstinence. Alcohol Clin Exp Res 21:1285-1293
8. Froehlich JC, Harts J, Lumeng L, Li TK (1988) Differences in response to the aversive properties of ethanol in rats selectively bred for oral ethanol preference. Pharmacol Biochem Behav 31:215-222
9. Geracioti TD Jr, Loosen PT, Ebert MH, Ekhator NN, Burns D, Nicholson WE, Orth DN (1994) Concentrations of corticotropin-releasing hormone, norepinephrine, MHPG, 5-hydroxyindoleacetic acid, and tryptophan in the cerebrospinal fluid of alcoholic patients: serial sampling studies. Neuroendocrinology 60:635-642
10. Heinrichs SC, Stenzel-Poore MP, Gold LH, Battenberg E, Bloom FE, Koob GF, Vale WW, Pich EM (1996) Learning impairment in transgenic mice with central overexpression of corticotropin-releasing factor. Neuroscience 74:303-311
11. Hundt W, Zimmermann U, Pottig M, Spring K, Holsboer (2001) The combined dexamethasone-suppression/CRH-stimulation test in alcoholics during and after acute withdrawal. Alcohol Clin Exp Res 25:687-691
12. Kampov-Polevoy AB, Garbutt JC, Janowsky DS (1999) Association between preference for sweets and excessive alcohol intake: a review of animal and human studies. Alcohol Alcohol 34:386-395
13. Koob GF, Roberts AJ, Schulteis G, Parsons LH, Heyser CJ, Hyytia P, Merlo-Pich E, Weiss F (1998) Neurocircuitry targets in ethanol reward and dependence. Alcohol Clin Exp Res 22:3-9
14. Le AD, Quan B, Juzytch W, Fletcher PJ, Joharchi N, Shaham Y (1998) Reinstatement of alcohol-seeking by priming injections of alcohol and exposure to stress in rats. Psychopharmacology 135:169-174
15. Lessov CN, Risinger FO, Phillips TJ (2001) Attenuation of ethanol-induced conditioned taste aversion in mice sensitized to the locomotor stimulant effects of ethanol. Behav Neurosci 115:146-153
16. Luczak SE, Elvine-Kreis B, Shea SH, Carr LG, Wall TL (2002) Genetic risk for alcoholism relates to level of response to alcohol in Asian-American men and women. J Stud Alcohol 63:74-82
17. Martin-Fardon R, Ciccocioppo R, Massi M, Weiss F (2000) Nociceptin prevents stress-induced ethanol- but not cocaine-seeking behavior in rats. Neuroreport 11:1939-1943
18. McBride WJ, Le AD, Noronha A (2002) Central nervous system mechanisms in alcohol relapse. Alcohol Clin Exp Res 26:280-286
19. Menzaghi F, Rassnick S, Heinrichs S, Baldwin H, Pich EM, Weiss F, Koob GF (1994) The role of corticotropin-releasing factor in the anxiogenic effects of ethanol withdrawal. Ann N Y Acad Sci 739:176-184
20. Merlo Pich E, Lorang M, Yeganeh M, Rodriguez de Fonseca F, Raber J, Koob GF, Weiss F (1995) Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis. J Neurosci 15:5439-5447
21. Olive MF, Koenig HN, Nannini MA, Hodge CW (2002) Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake. Pharmacol Biochem Behav 72:213-220
22. Olive MF, Mehmert KK, Koenig HN, Camarini R, Kim JA, Nannini MA, Ou CJ, Hodge CW (2003) A role for corticotropin releasing factor (CRF) in ethanol consumption, sensitivity, and reward as revealed by CRF-deficient mice. Psychopharmacology 165:181-187
23. Palmer AA, Phillips TJ (2002) Effect of forward and reverse selection for ethanol-induced locomotor response on other measures of ethanol sensitivity. Alcohol Clin Exp Res 26:1322-1329
24. Phillips TJ, Crabbe JC, Metten P, Belknap JK (1994) Localization of genes affecting alcohol drinking in mice. Alcohol Clin Exp Res 18:931-941
25. Phillips TJ, Belknap JK, Buck KJ, Cunningham CL (1998) Genes on mouse chromosomes 2 and 9 determine variation in ethanol consumption. Mamm Genome 9:936-941
26. Risinger FO, Cunningham CL (1998) Ethanol-induced conditioned taste aversion in BXD recombinant inbred mice. Alcohol Clin Exp Res 22:1234-1244
27. Rivier C, Imaki T, Vale W (1990) Prolonged exposure to alcohol: effect on CRF mRNA levels, and CRF- and stress-induced ACTH secretion in the rat. Brain Res 520:1-5
28. Rodd ZA, Bell RL, Kuc KA, Murphy JM, Lumeng L, Li TK, McBride WJ (2003) Effects of repeated alcohol deprivations on operant ethanol self-administration by alcohol-preferring (P) rats. Neuropsychopharmacology 28:1614-1621
29. Schuckit MA (1994) Low level of response to alcohol as a predictor of future alcoholism. Am J Psychiatry 151:184-189
30. Schuckit MA, Smith TL (2001) The clinical course of alcohol dependence associated with a low level of response to alcohol. Addiction 96:903-910
31. Sinha R (2001) How does stress increase risk of drug abuse and relapse? Psychopharmacology 158:343-359
32. Shen EH, Harland RD, Crabbe JC, Phillips TJ (1995) Bidirectional selective breeding for ethanol effects on locomotor activity: characterization of FAST and SLOW mice through selection generation 35. Alcohol Clin Exp Res 19:1234-1245
33. Stenzel-Poore MP, Cameron VA, Vaughan J, Sawchenko PE, Vale W (1992) Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice. Endocrinology 130:3378-3386
34. Terdal ES, Crabbe JC (1994) Indexing withdrawal in mice: matching genotypes for exposure in studies using ethanol vapor inhalation. Alcohol Clin Exp Res 18:542-547
35. Valdez GR, Roberts AJ, Chan K, Davis H, Brennan M, Zorrilla EP, Koob GF (2002) Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor. Alcohol Clin Exp Res 26:1494-1501
36. Waltman C, McCaul ME, Wand GS (1994) Adrenocorticotropin responses following administration of ethanol and ovine corticotropin-releasing hormone in the sons of alcoholics and control subjects. Alcohol Clin Exp Res 18:826-830
37. Zimmermann U, Hundt W, Spring K, Grabner A, Holsboer F (2003) Hypothalamic-pituitary-adrenal system adaptation to detoxification in alcohol-dependent patients is affected by family history of alcoholism. Biol Psychiatry 53:75-84