Protamine after heparin produces hypotension resulting from decreased sympathetic outflow secondary to increased nitric oxide in the central nervous system

Anesthesia and Analgesia

Volumn 100, Issue 1, 2005, Pages 33-37

  Hamada, Yoshikazu ^a   Kameyama, Yoshiyuki ^a   Narita, Hideyuki ^a   Benson, Kirk T ^b   Goto, Hiroshi ^b  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROTAMINE SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTONOMIC DENERVATION; CARDIOVASCULAR EFFECT; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; HEART RATE; HEMODYNAMICS; HYPOTENSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSORECEPTOR; PRIORITY JOURNAL; RABBIT; RENAL SYMPATHETIC NERVE ACTIVITY; STATISTICAL SIGNIFICANCE; SYMPATHETIC OUTFLOW; SYMPATHETIC TONE;

ANIMALS; BLOOD PRESSURE; CENTRAL NERVOUS SYSTEM; DENERVATION; ENZYME INHIBITORS; HEART RATE; HEPARIN; HEPARIN ANTAGONISTS; HYPOTENSION; KIDNEY; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PRESSORECEPTORS; PROTAMINES; RABBITS; SYMPATHETIC NERVOUS SYSTEM;

EID: 10944271744     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000139357.87358.94     Document Type: Article

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