Autoimmune hemolytic anemia with giant cell hepatitis: Case report and review of the literature

Journal of Pediatric Hematology/Oncology

Volumn 26, Issue 12, 2004, Pages 837-839

  Gorelik, Mark ^a   Debski, Robert ^a   Frangoul, Haydar ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Autoimmune hemolytic anemia; Giant cell hepatitis; Rituximab

Indexed keywords

AUTOANTIBODY; AZATHIOPRINE; COMPLEMENT COMPONENT C3; CYCLOSPORIN A; CYTOTOXIC AGENT; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; LIVER ENZYME; PREDNISONE; RITUXIMAB; STEROID; VINCRISTINE;

ANEMIA; AUTOIMMUNE HEMOLYTIC ANEMIA; BLOOD TRANSFUSION; CASE REPORT; CLINICAL TRIAL; COOMBS TEST; DISEASE ASSOCIATION; DISEASE COURSE; DRUG EFFICACY; DRUG SAFETY; ERYTHROCYTE TRANSFUSION; FATALITY; FEMALE; GIANT CELL HEPATITIS; HEPATITIS; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; INFANT; LIVER BIOPSY; LIVER FAILURE; MEDICAL LITERATURE; META ANALYSIS; PLASMAPHERESIS; PRIORITY JOURNAL; PROGNOSIS; RARE DISEASE; REVIEW; SPLENECTOMY; STEROID THERAPY; SYSTEMATIC REVIEW;

ANEMIA, HEMOLYTIC, AUTOIMMUNE; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; FEMALE; GIANT CELLS; HEPATITIS; HUMANS; INFANT; TREATMENT OUTCOME;

EID: 10944264610     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (15)

1. Gehrs BC, Friedberg RC. Autoimmune hemolytic anemia. Am J Hematol. 2002;69:258-271.
2. Hartman C, Berkowitz D, Brik R, et al. Giant cell hepatitis with autoimmune hemolytic anemia and hemophagocytosis. J Pediatr Gastroenterol Nutr. 2001;32:330-334.
3. Hadzic M, Portmann B, Lewis I, et al. Coombs-positive giant cell hepatitis: a new feature of Evans' syndrome. Arch Dis Child. 1998;78:397-398.
4. Melendez HV, Rela M, Baker AJ, et al. Liver transplant for giant cell hepatitis with autoimmune hemolytic anemia. Arch Dis Child. 1997;77:249-251.
5. Perez-Atayade AR, Sirlin SM, Jonas M. Coombs-positive autoimmune hemolytic anemia and post-infantile giant cell hepatitis in children. Pediatr Pathol. 1994;14:69-77.
6. Weinstein T, Valderrmana E, Pettei M, et al. Early steroid therapy for the treatment of giant cell hepatitis with autoimmune hemolytic anemia. J Pediatr Gastroenterol Nutr. 1993;17:313-316.
7. Gottardo NG, Baker DL, Willis FR. Successful induction and maintenance of long-term remission in a child with chronic relapsing autoimmune hemolytic anemia using rituximab. Pediatr Hematol Oncol. 2003;20:557-561.
8. Ahrens N, Kingreen D, Seltsam A, et al. Treatment of refractory autoimmune hemolytic anemia with anti-CD20 (rituximab). Br J Hematol. 2001;114:244-245.
9. Motto DG, Williams JA, Boxer LA. Rituximab for refractory childhood autoimmune hemolytic anemia. Isr Med Assoc J. 2002;4:1006-1008.
10. Koukoulis G, Mieli-Vergani G, Portmann B. Infantile liver cells: immunohistological study of their proliferative state and possible mechanisms of formation. Pediatr Dev Pathol. 1999;2:353-359.
11. Rogoff TM, Lipsky PE. Role of the Kupffer cells in local and systemic immune responses. Gastroenterology. 1981;80:854-860.
12. Brichard B, Sokal E, Gosseye S, et al. Coombs-positive giant cell hepatitis of infancy: effect of steroids and azathioprine therapy. Eur J Pediatr. 1991;150:314-317.
13. Imgrueth M, Wagner HP, Pipczynski-Suter K, et al. Plasma exchange: an important part of the therapeutic procedure in a small child with autoimmune hemolytic anemia. Acta Pediatr Scand. 1986;75:1037-1041.
14. Bernard O, Hadchoel M, Scotto J, et al. Severe giant cell hepatitis with autoimmune hemolytic anemia in early childhood. J Pediatr. 1981;99:704-711.
15. Zecca M, Nobili B, Ramenghi U, et al. Rituximab for the treatment of refractory autoimmune hemolytic anemia in children. Blood. 2003;101:3857-3867.