Successful reversal of deleterious coagulopathy by recombinant factor VIIa

Anesthesia and Analgesia

Volumn 100, Issue 1, 2005, Pages 54-58

  Haas, Thorsten ^a   Innerhofer, Petra ^a   Kühbacher, Gabriele ^a   Fries, Dietmar ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT BLOOD CLOTTING FACTOR 7A;

ADULT; AGED; ARTICLE; BLEEDING; BLOOD CLOTTING DISORDER; BLOOD TRANSFUSION; CASE REPORT; CONVALESCENCE; DISEASE COURSE; DRUG COST; FEMALE; HEALTH CARE COST; HEMOSTASIS; HUMAN; INTENSIVE CARE; MALE; MULTIPLE ORGAN FAILURE; OPERATING ROOM; PRIORITY JOURNAL; SEPSIS; SIDE EFFECT; WOUND;

ADULT; AGED; AORTA; AORTIC VALVE STENOSIS; BLOOD COAGULATION DISORDERS; BLOOD COAGULATION TESTS; BLOOD LOSS, SURGICAL; CHOLECYSTECTOMY, LAPAROSCOPIC; FACTOR VIIA; FATAL OUTCOME; FEMALE; HEART VALVE PROSTHESIS IMPLANTATION; HEMODYNAMIC PROCESSES; HEMORRHAGE; HUMANS; MALE; MARFAN SYNDROME; MIDDLE AGED; MULTIPLE TRAUMA; POSTOPERATIVE HEMORRHAGE; RECOMBINANT PROTEINS; SUICIDE, ATTEMPTED;

EID: 10944242280     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000138064.12583.F6     Document Type: Article

References (19)

1. Hedner U, Erhardtsen E. Potential role for rFVIIa in transfusion medicine. Transfusion 2002;42:114-24.
2. Lusher J, Ingerslev J, Roberts H, Hedner U. Clinical experience with recombinant factor VIIa. Blood Coagul Fibrinolysis 1998;9:S119-28.
3. Martinowitz U, Holcomb JB, Pusateri AE, et al. Intravenous rFVIIa administered for hemorrhage control in hypothermic coagulopathic swine with grade V liver injuries. J Trauma 2001;50:721-9.
4. Schreiber MA, Holcomb JB, Hedner U, et al. The effect of recombinant factor VIIa on coagulopathic pigs with grade V liver injuries. J Trauma 2002;53:252-9.
5. Weiskopf RB. Intraoperative use of recombinant activated coagulation factor VII. Anesthesiology 2002;96:1287-9.
6. Anthony MH, Dion PW, Karmaker MK. Use of recombinant activated factor VII in patients with severe coagulopathy and bleeding. Anesthesiology 2003;98:1025-6.
7. Shih RL, Cherng YG, Chao A, et al. Predicting of bleeding diathesis in patients undergoing cardiopulmonary bypass during cardiac surgery: viscoelastic measures versus routine coagulation test. Acta Anaesthesiol Sin 1997;35:133-9.
8. Chee YL, Greaves M. Role of coagulation testing in predicting bleeding risk. Hematol J 2003;4:373-8.
9. Eckman MH, Erban JK, Singh SK, Kao GS. Screening for the risk for bleeding or thrombosis. Ann Intern Med 2003;138:W15-24.
10. Practice guidelines for blood component therapy: a report by the American Society of Anesthesiologists Task Force on Blood Component Therapy. Anesthesiology 1996;84:732-47.
11. Reiss RF. Hemostatic defects in massive transfusion: rapid diagnosis and management. Am J Crit Care 2000;9:158-65; quiz 66-7.
12. Chowdhury P, Saayman AG, Paulus U, et al. Efficacy of standard dose and 30ml/kg fresh frozen plasma in correcting laboratory parameters of haemostasis in critically ill patients. Br J Haematol 2004;125:69-73.
13. Cammerer U, Dietrich W, Rampf T, et al. The predictive value of modified computerized thrombelastography and platelet function analysis for postoperative blood loss in routine cardiac surgery. Anesth Analg 2003;96:51-7.
14. Miller B, Mochizuki T, Levy J, et al. Predicting and treating coagulopathies after cardiopulmonary bypass in children. Anesth Analg 1997;85:1196-202.
15. Martinowitz U, Kenet G, Segal E, et al. Recombinant activated factor VII for adjunctive hemorrhage control in trauma. J Trauma 2001;51:431-8.
16. Vidarsson B, Önundarson PT. Recombinant factor VIIa for bleeding in refractory thrombocytopenia. Thromb Haemost 2000;83:634-5.
17. Heuer L, Blumenberg D. Recombinant factor VIIa (Novoseven): a review of current and possible future indications. Anaesthesist 2002;51:388-99.
18. Friederich P, Christiaan C, Messelink E, et al. Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: a double-blind placebo-controlled randomised trial. Lancet 2003;361:201-5.
19. Kawaguchi C, Takahashi Y, Hanesaka Y, Yoshioka A. The in vitro analysis of the coagulation mechanism of activated factor VII using thrombelastogram. Thromb Haemost 2002;88:768-72.