Condensation of chromone-3-carboxaldehyde with phenylacetic acids: An efficient synthesis of (E)-3-styrylchromones

Synlett

Volumn , Issue 15, 2004, Pages 2717-2720

  Silva, Vera L M ^a   Silva, Artur M S ^a   Pinto, Diana C G A ^a   Cavaleiro, José A S ^a   Patonay, Tamás ^b  

^a UNIVERSITY OF AVEIRO   (Portugal)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

(E) 3 styrylchromones; Chromone 3 carboxaldehyde; Condensation; Microwave irradiation; Phenylacetic acids

Indexed keywords

3 STYRYLCHROMONE; ALDEHYDE; BUTANE; CHROMONE 3 CARBOXALDEHYDE; CHROMONE DERIVATIVE; OXIDE; PHENYLACETIC ACID; POTASSIUM; POTASSIUM TERT BUTOXIDE; STYRENE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DECARBOXYLATION; DIASTEREOISOMER; HEATING; KNOEVENAGEL CONDENSATION; MICROWAVE RADIATION; POLYMERIZATION; REACTION TIME; STEREOCHEMISTRY; SYNTHESIS;

EID: 10844286205     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-835660     Document Type: Article

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31. 2-light petroleum ether as eluent. The obtained residue was crystallised from EtOH giving 3-styrylchromones 3a-g in good yields (Table 3).
32. 3), 123.0 (C-α), 124.1 (C-10), 125.4 (C-6), 125.9 (q, 1 H, J = 5.7 Hz, C-β), 126.3 (C-5), 127.0 (q, J = 2.2 Hz, C-3′), 127.1 (C-6′), 127.5 (C-4′), 127.6 (q, J = 29.8, C-2′), 131.9 (C-5′), 133.7 (C-7), 136.3 (q, J = 1.7 Hz, C-1′), 153.3 (C-2), 155.9 (C-9), 176.5 (C-4).
33. 4N: C, 69.62; H, 3.78; N, 4.78. Found: C, 69.57; H, 3.79; N, 4.75.
34. 2-light petroleum ether as eluent. The obtained residue was crystallised from EtOH giving 3-styrylchromones 3a-g in good yields (3a, 86.2%; 3b, 79.9%; 3c, 90.9%; 3d, 56.0%; 3e, 90.3%; 3f, 94.1%; 3g, 80.2%).
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