Stress lactate in mitochondrial myopathy under constant, unadjusted workload

European Journal of Neurology

Volumn 11, Issue 12, 2004, Pages 811-816

  Finsterer, Josef ^a   Milvay, E ^a  

^a Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhugel   (Austria)

Author keywords

Exercise stress test; Lactacidosis; Metabolic disorder; Neuromuscular disorder; Respiratory chain

Indexed keywords

CREATINE KINASE; LACTIC ACID;

ADULT; AEROBIC METABOLISM; AGE DISTRIBUTION; AGED; ARTICLE; AUSTRIA; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; ELECTROMYOGRAPHY; EXERCISE TEST; FEMALE; HUMAN; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MITOCHONDRIAL MYOPATHY; NEUROLOGIC DISEASE; PHYSICAL STRESS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; WORKLOAD;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; COHORT STUDIES; ERGOMETRY; EXERCISE TEST; FEMALE; HUMANS; LACTIC ACID; MALE; MIDDLE AGED; MITOCHONDRIAL MYOPATHIES; NERVOUS SYSTEM DISEASES; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; WORKLOAD;

EID: 10844268817     PISSN: 13515101     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2004.00859.x     Document Type: Article

References (17)

1. Abe K, Matsuo Y, Kadekawa J, Inoue S, Yanagihara T (1997). Measurement of tissue oxygen consumption in patients with mitochondrial myopathy by non-invasive tissue oximetry. Neurology 49:837-841.
2. Chan A, Gold R, Arp S, Pflughaupt KW, Toyka KV, Reichmann R (1998). A standardised bicycle ergometer test in the diagnosis and monitoring of mitochondrial myopathies. Nervenarzt 69:472-484.
3. Dandurand RJ, Matthews PM, Arnold DM, Eidelman DH (1995). Mitochondrial disease. Pulmonary function, exercise performance and blood lactate levels. Chest 108:182-189.
4. Dengler R, Wohlfarth K, Zierz S, Jöbges M, Schubert M (1996). Muscle fatigue, lactate, and pyruvate in mitochondrial myopathy with progressive external ophthalmoplegia. Muscle Nerve 19: 456-462.
5. Finsterer J, Milvay E (2001). Diagnostic yield of the lactate stress test in respiratory chain disorders under absolute or relative workload. J Neurosci Meth 108:65-70.
6. Finsterer J, Milvay E (2002). Lactate stress testing in 155 patients with respiratory chain disorders. Can J Neurol Sci 29:49-53.
7. Finsterer J, Obermann I, Milvay E (2000). Diagnostic yield of the lactate stress test in 160 patients with suspected respiratory chain disorder. Metab Brain Dis 15:163-171.
8. Haller RG, Bertocci LA (1994). Exercise evaluation of metabolic myopathies. In: Engel AG, Franzini-Armstrong C, eds. Myology. Basic and clinical. McGraw-Hill, New York, pp. 807-821.
9. Jackson MJ, Schaefer JA, Johnson MA, Morris AAM, Turnbull DM, Bindoff LA (1995). Presentation and clinical investigation of mitochondrial respiratory chain disease. A study of 51 patients. Brain 118:339-357.
10. Jeppesen TD, Olsen D, Vissing J (2003). Cycle ergometry is not a sensitive diagnostic test for mitochondrial myopathy. J Neurol 250:293-299.
11. Morgan-Hughes JA (1994). The mitochondrial myopathies. In: Engel AG, Franzini-Armstrong C, eds. Myology. Basic and clinical. McGraw-Hill, New York, pp. 1610-1651.
12. Schapira AHV, DiMauro S (1994). Mitochondrial Disorders in Neurology. Butterworth Heinemann, Oxford, pp. 75-76.
13. Schmidt M, Kunkel M, Schuff-Werner P, Naumann M, Reichmann H, Reimers CD (1997). Standardised aerobic treadmill ergometry in healthy subjects and patients with mitochondrial and non-mitochondrial myopathies. Nervenarzt 68:831-835.
14. Siciliano G, Rossi B, Manca L et al. (1996). Residual muscle cytochrome c oxidase activity accounts for submaximal exercise lactate threshold in chronic external ophthalmoplegia. Muscle Nerve 9:342-349.
15. Siciliano G, Renna M, Nanca ML et al. (1999). The relationship of plasma catecholamine and lactate during anaerobic threshold exercise in mitochondrial myopathies. Neuromusc Disord 9:411-416.
16. VanHall G (2000). Lactate as a fuel for mitochondrial respiration. Acta Physiol Scand 168:643-656.
17. Vissing J, Galbo H, Haller RG (1996). Exercise fuel mobilisation in mitochondrial myopathy: a metabolic dilemma. Ann Neurol 40:655-662.