Can urinary uric acid/creatinine ratio be used as an additional marker for neonatal asphyxia?

International Pediatrics

Volumn 19, Issue 4, 2004, Pages 217-219

  Erdag, Gulay Ciler ^a,b   Vitrinel, A ^a  

^a Dr Lutfi KNrdar Kartal Training and Research Hospital   (Turkey)

^b NONE   (Turkey)

Author keywords

Hypoxic ischemic encephalopathy (HIE); Perinatal asphyxia; Uric acid creatinine

Indexed keywords

CREATININE; URIC ACID;

ARTICLE; BLOOD PH; BRAIN DISEASE; CHI SQUARE DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC VALUE; DISEASE MARKER; DISEASE SEVERITY; EVALUATION; FEMALE; HUMAN; HYPOXIC ISCHEMIC ENCEPHALOPATHY; MALE; NEWBORN; NEWBORN HYPOXIA; NON INVASIVE MEASUREMENT; PERINATAL PERIOD; PROGNOSIS; RANK SUM TEST; SCORING SYSTEM; UMBILICAL CORD BLOOD; URINALYSIS; VALIDATION PROCESS;

EID: 10844256633     PISSN: 08856265     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. John Hc Menkes and Harvey B. Sarnat. Perinatal asphyxia and trauma. In: Menkes H, Sarnat H, ed. Child Neurology. Philadelphia, MD:Williams and Wilkins 2000;401-455.
2. th ed. Philadelphia: WB Saunders Company;2000:493-496.
3. Fenichel GM. Hypoxic-ischemic encephalopathy in the newborn. Arch Neurol 1983;40:261-6.
4. Finer NN, Robertson CM, Richards RT, Pinnell LE, Peters KL. Hypoxic-ischemic encephalopathy in term neonates: perinatal factors and outcome. J Pediatr 1981;98:112-7.
5. rd ed. WB Saunders Company, 1995;211-360.
6. Perlman J. Markers of asphyxia and neonatal brain injury. N Engl J Med 1999;341:363-5.
7. Marlow N. Do we need an Apgar score? Arch Dis Child 1992;67:765-7.
8. Swanstrom S, Bratteby LE. Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit and pH. Pediatr Res. 1982;16:156-60.
9. Poulsen JP, Rognum TO, Oyasaeter S, Saugstad OD. Changes in oxypurine concentration in vitreus humor pigs during hypoxemia and post-mortem. Pediatr Res 1990;28:482-84.
10. Poulsen JP, Oyasaeter S, Sanderud J, Rognum TO, Saugstod OD. Hypoxanthine, xanthine, and uric acid concentration in the cerebrospinal fluid, plasma and urine of hypoxemic pigs. Pediatr Res 1990;28:477-81.
11. Porter KB, O'Brien WF, Benoit R. Comparison of cord purine metabolites to maternal and neonatal variables of hypoxia. Obstet Gynecol 1992;79:394-7.
12. Palmer C, Vannucci RC, Towfighi J. Reduction of perinatal hypoxic-ischemic brain damage with allopurinol. Pediatr Res 1990;27:332-6.
13. Vannucci RC. Cerebral carbohydrate and energy metabolism in perinatal hypoxic-ischemic brain damage. Brain Pathol 1992;2:229-34.
14. Vannucci RC, Yager JY. Glucose, lactic acid, and perinatal hypoxic-ischemic brain damage. Pediatr Neurol 1992;8:3-12.
15. Rivkin MJ, Volpe JJ. Hypoxic-ischemic brain injury in the newborn. Semin Neurol 1993;13:30-9.
16. Mallard EC, Gunn AJ, Williams CE, Johnston BM, Gluckman PD. Transient umbilical cord occlusion causes hippocampal damage in the fetal sheep. Am J Obstet Gynecol 1992;167:1423-30.
17. Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch Neurol 1976;33:696-705.
18. Verdu Perez A, Falero MP, Arroyos A, et al. Blood neuronal specific enolase in newborns with perinatal asphyxia. Rev Neurol 2001;32:714-7.
19. Groenendaal F, de Vries LS. Selection of babies for intervention after birth asphyxia. Semin Neonatol 2000;5:17-32.
20. Bader D, Gozal D, Weinger-Abend M, Berger A, Lanir A. Neonatal urinary uric acid/creatinine ratio as additional marker of perinatal asphyxia. Eur J. Pediatr 1995;154:747-9.
21. Akisu M, Kültürsay N. Value of the urinary uric acid to creatinine ratio in term infants with perinatal asphyxia. Acta Paediatr Jpn 1998;40:78-81.
22. Chen HJ, Yau KI, Tsai KS. Urinary uric acid/creatinine ratio as an additional marker of perinatal asphyxia. J Formos Med Assoc 2000;99:771-4.
23. Christensen EF, Jacobsen J, Anker-Moller E, Schultz P, Spangsberg N. Increased urinary loss of uric acid in adults with acute respiratory failure requiring mechanical ventilation. Chest 1992;102:556-9.
24. Jensen MH, Brinklov MM, Lillquist K. Urinary loss of oxypurines in hypoxic premature neonates. Biol Neonate 1980;38:40-8.
25. Mehes K, Horvath I, Szakolczai I. Uric acid in a single urine sample from neonates with perinatal hypoxia. Acta Paediatr Acad Sci Hung 1981;22:43-7.