A novel lectin (Morniga M) from Mulberry (Morus nigra) bark recognizes oligomannosyl residues in N-glycans

Journal of Biomedical Science

Volumn 11, Issue 6, 2004, Pages 874-885

  Wu, Albert M ^a   Wu, June H ^b   Singh, Tanuja ^a   Chu, Kang Chuang ^a   Peumans, Willy J ^c   Rougé, Pierre ^d   Van Damme, Els J M ^c  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c GHENT UNIVERSITY   (Belgium)

^d Centre National de la Recherche Scientifique   (France)

Author keywords

Carbohydrate specificity; Glycoproteins; Jacalin related lectin; Morniga M; Morus nigra; N glycans; Oligomannosyl residues

Indexed keywords

CARBOHYDRATE; GLYCAN DERIVATIVE; LECTIN; LIGAND; MANNOSE; MORNIGA M; OROSOMUCOID; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; BARK; BINDING AFFINITY; BIOTECHNOLOGY; CARBOHYDRATE ANALYSIS; CELL SURFACE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; MULBERRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PURIFICATION;

ANIMALS; CARBOHYDRATE SEQUENCE; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOPROTEINS; LECTINS; LIGANDS; MANNOSE; MOLECULAR SEQUENCE DATA; MORUS; OLIGOSACCHARIDES; OROSOMUCOID; PLANT LECTINS; PLANT PROTEINS; POLYSACCHARIDES;

BOVINAE; MORUS (PLANT); MORUS NIGRA;

EID: 10844252908     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1159/000081835     Document Type: Article

References (30)

1. DeVries AL, Komatsu SK, Feeney RE. Chemical and physical properties of freezing pointdepressing glycoproteins from Antarctic fishes. J Biol Chem 245:2901-2908;1970.
2. a-active Tamm-Horsfall urinary glycoprotein. Biochem Biophys Res Commun 93:1132-1139;1982.
3. Duk M, Lisowska E, Wu JH, Wu AM. The biotin/avidin-mediated microtiter plate lectin assay with the use of chemically modified glycoprotein ligand. Anal Biochem 221:266-272;1994.
4. Kabat EA. Blood Group Substances: Their Chemistry and Immunochemistry. New York, Academic Press, 135-139;1956.
5. Lindberg B, Lönngren J, Powell DA. Structural studies on the specific type-14 pneumococcal polysaccharide. Carbohydr Res 58:177-186;1977.
6. Lisowska E, Duk M, Wu AM. Preparation of biotinylated lectins and application in microtiter plate assays and Western blotting. Biomethods 7:115-129;1996.
7. Rosa JC, De Oliveira PSL, Garratt R, Beltramini L, Resing K, Roque-Barreira MC, Greene LJ. KM+, a mannose-binding lectin from Artocarpus integrifolia: Amino acid sequence, predicted tertiary structure, carbohydrate recognition, and analysis of the β-prism fold. Protein Sci 8:13-24;1999.
8. Rougé P, Peumans WJ, Barre A, Van Damme EJM. A structural basis for the difference in specificity between the two jacalin-related lectins from mulberry (Morus nigra) bark. Biochem Biophys Res Commun 304:91-97;2003.
9. Sharon N, Lis H. Lectins. London, Kluwer Academic Publishers, 2003.
10. Song SC, Chen YY, Herp A, Tsai MS, Wu AM. Lectinochemical characterization of a GalNAc and multi-Galβ1-4GlcNAc reactive lectin from Wistaria sinensis seeds. Eur J Biochem 266:1-16;1999.
11. Tettamanti G, Pigman W. Purification and characterization of bovine and ovine submaxillary mucins. Arch Biochem Biophys 124:41-50;1968.
12. Van Damme EJM, Hause B, Hu J, Barre A, Rougé P, Proost P, Peumans WJ. Two-distinct jacalin-related lectins with a different specificity and subcellular location are major vegetative storage proteins in the bark of the black mulberry tree. Plant Physiol 130:757-769;2002.
13. Van Damme EJM, Peumans WJ, Barre A, Rougé P. Plant lectins: A composite of several distinct families of structurally and evolutionary related proteins with diverse biological roles. Crit Rev Plant Sci 17:575-692;1998.
14. b, I and i active glycoprotein purified from human ovarian cyst fluid. Adv Exp Med Biol 228:351-392;1988.
15. Wu AM. Expression of binding properties of Gal/GalNAc reactive lectins by mammalian glycotopes. Adv Exp Med Biol 491:55-64;2001.
16. Wu AM. Carbohydrate Structural Units in Glycosphingolipids as Receptors for Gal and GalNAc Reactive Lectins. Neurochem Res 27:593-600;2002.
17. Wu AM. Carbohydrate structural units glycoproteins and polysaccharides as important ligands for Gal and GalNAc reactive lectins. J Biomed Sci 10:676-688;2003.
18. Wu AM. Polyvalency of Tn (GalNAcα→Ser/Thr) glycotope as a critical factor for Vicia villosa B4 and glycoprotein interactions. FEBS Lett 562:51-58;2004.
19. Wu AM, Pigman W. Preparation and characterization of armadillo submandibular glycoproteins. Biochem J 161:37-47;1977.
20. 3H reduction of Smith degraded blood group A active glycoproteins. J Biol Chem 259:7178-7186;1984.
21. Wu AM, Kabat EA, Pereira MEA, Gruezo FG, Liao J. Immunochemical studies on blood groups: The internal structure and immunological properties of water-soluble human blood group A substance studied by Smith degradation, liberation and fractionation of oligosaccharides and reaction with lectins. Arch Biochem Biophys 215:390-404;1982.
22. Wu AM, Lin SR, Chin LK, Chow LP, Lin JY. Defining the carbohydrate specificities of Abrus precatorius agglutinin as T (Galβ1→3GalNAc) > I/II (Galβ1→3/4GlcNAc). J Biol Chem 267:19130-19139;1992.
23. Wu AM, Song SC, Chang SC, Wu JH, Chang KS, Kabat EA. Further characterization of the binding properties of a GalNAc specific lectin from Codium fragile subspecies tomentosoides. Glycobiology 7:1061-1066;1997.
24. Wu AM, Song SC, Chen YY, Nechama GG. Defining the carbohydrate specificities of aplysia gonad lectin exhibiting a peculiar D-galacturonic acid affinity. J Biol Chem 275:14017-14024;2000.
25. Wu JH, Song SC, Chen YY, Tsai MC, Kabat EA, Wu AM. Multi-antennary Gal β1→4GlcNAc and Galβ1→3GalNAc clusters as important ligands for a lectin isolated from the sponge Geodia cydonium. FEBS Lett 427:134-138;1998.
26. Wu AM, Watkins WM, Chen CP, Song SC, Chow LP, Lin JY. Native and/or asialo Tamm-Horsfall glycoproteins Sd (a+) are important receptors for Triticum vulgaris (wheat germ) agglutinin and for three toxic lectins (abrin-a, ricin and mistletoe toxic lectin-I). FEBS Lett 371:32-34;1995.
27. 4). Glycobiology 9:1161-1170;1999.
28. Wu AM, Wu JH, Chen YY, Tsai MS, Herp A. Carbohydrate specificities of an agglutinin isolated from the root of Trichosanthes kirilowii. Life Sci 66:2571-2581;2000.
29. Wu AM, Wu JH, Herp A, Liu JH. Effect of polyvalencies of glycotopes on the binding of a lectin from the edible mushroom, Agaricus bisporus. Biochem J 371:311-320;2003.
30. Wu AM, Wu JH, Liu JH, Singh T. Recognition profile of Bauhinia purpurea agglutinin (BPA). Life Sci 74:1763-1779;2004.