Conformational change of glyceraldehyde-3-phosphate dehydrogenase induced by acetylleucine chloromethyl ketone is followed by unique enzymatic degradation

Biological and Pharmaceutical Bulletin

Volumn 26, Issue 12, 2003, Pages 1648-1651

  Yamaguchi, Mitsune ^a   Tsuchiya, Yukihiro ^a   Hishinuma, Kayoko ^a   Chikuma, Toshiyuki ^a   Hojo, Hiroshi ^a  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Acetylleucine chloromethyl ketone (ALCK); Chymotrypsin like protease; Glyceraldehyde 3 phosphate dehydrogenase; U937 cell extract

Indexed keywords

ACETYLLEUCINE CHLOROMETHYL KETONE; CELL EXTRACT; CHYMOTRYPSIN; CHYMOTRYPSIN INHIBITOR; ENZYME ANTIBODY; ENZYME INHIBITOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; KETONE DERIVATIVE; PROTEINASE; TOSYLLYSYL CHLOROMETHYL KETONE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG;

ALKALINITY; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CELL STRAIN U937; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MODIFICATION; FLUORESCENCE; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; SEQUENCE ANALYSIS; ULTRAVIOLET RADIATION; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; AMINO ACIDS; BLOTTING, WESTERN; CELL EXTRACTS; CHYMASES; CIRCULAR DICHROISM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ERYTHROCYTES; FLUORESCENCE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN DENATURATION; SERINE ENDOPEPTIDASES; SPECTROMETRY, FLUORESCENCE; U937 CELLS;

EID: 10844225370     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.26.1648     Document Type: Article

References (20)

1. Yamaguchi M., Kambayashi D., Toda J., Sano T., Toyoshima S., Hojo H , Biochem Biophys. Res. Commun., 263, 139-142 (1999).
2. Yamaguchi M., Tsuchiya Y., Chikuma T., Hojo H., Biochem. Pharmcol., 63, 1857-1862 (2002).
3. Sirover M. A., Biochim Biophys Acta, 1432, 159-184 (1999)
4. Glaser P. E., Gross R. W., Biochemistry, 34, 12193-12203 (1995).
5. Launay J. F , Jellali A., Vanier M. T., Biochim. Biophys. Acta, 996, 103-109 (1989).
6. Engel M., Seifert M., Theisinger B., Seyfert U., Welter C., J Biol. Chem., 273, 20058-20065 (1998).
7. Zang W. Q., Fieno A M , Grant R. A., Yen T. S. B., Virology, 248, 46-52 (1998)
8. Sirover M A., J. Cell Biochem , 66, 133-140 (1997).
9. Meyer-Siegler K , Mauro D. J , Seal G , Wurzer J., deRiel J K., Sirover M. A., Proc Natl Acad. Sci , 88, 8460-8464 (1991).
10. Nakazawa M , Uehara T., Nomura Y., J. Neurochem , 68, 2493-2499 (1997).
11. Kim J W., Kim T. E., Kim Y. K., Kim Y. W., Kim S. J., Lee J. M., Kim I. K., Namkoong S. E , Antisense Nucleic Acid Drug Dev., 9, 507-513 (1999).
12. Fuertes G., Villarroya A., Knecht E., Int. J. Biochem Cell. Biol., 35, 651-664 (2003).
13. Wheatley D. N., Knecht E., Cervera J., Smith S., Cytobios., 74, 81-96 (1993).
14. Bradford M. M , Anal. Biochem., 72, 248-254 (1976).
15. Dimmeler S., Lottspeich F., Brune B., J. Biol Chem., 267, 16771-16774 (1992).
16. Sharma K K., Ortwerth B J , Eur. J Biochem , 216, 631-637 (1993)
17. Tso J. Y., Sun X -H., Kao T., Reece K. S., Wu R., Nucleic. Acids Res., 13, 2485-2502 (1985).
18. Aniento F., Roche E , Cuervo A. M., Knecht E., J Biol. Chem., 268, 10463-10470 (1993).
19. Cuervo A. M., Dice J. F., Knecht E., J. Biol Chem , 272, 5606-5615 (1997).
20. Cuervo A. M., Knecht E., Terlecky S. R., Dice J. F., Am. J. Physiol., 269, C1200-1208 (1995)