Pharmacological profile of 6,12-dihydro-3-methoxy-1-benzopyrano[3,4-b] [1,4]benzothiazin-6-one, a novel human estrogen receptor agonist

Biological and Pharmaceutical Bulletin

Volumn 25, Issue 3, 2002, Pages 335-341

  Jacquot, Yves ^a   Cleeren, Anny ^c   Laios, Ioanna ^c   Ma, Yan ^c   Boulahdour, Athem ^a   Bermont, Laurent ^b   Refouvelet, Bernard ^a   Adessi, Gérard ^b   Leclercq, Guy ^c   Xicluna, Alain ^a  

^a UNIVERSITÉ DE FRANCHE COMTÉ   (France)

^b Lab d'Oncol d'Endocrinol Molec   (France)

^c JULES BORDET INSTITUTE   (Belgium)

Author keywords

Benzopyrano 3,4 b 1,4 benzothiazin 6 ones; Binding mode; Coumestrol; Estrogenicity; Ionic microscopy; MVLN

Indexed keywords

6,12 DIHYDRO 3 METHOXY 1 BENZOPYRANO[3,4 B][1,4]BENZOTHIAZIN 6 ONE; COUMESTROL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; LUCIFERASE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; UNCLASSIFIED DRUG; 6,12 DIHYDRO 3 METHOXY 1 BENZOPYRANO(3,4 B) (1,4)BENZOTHIAZIN 6 ONE; 6,12-DIHYDRO-3-METHOXY-1-BENZOPYRANO(3,4-B)-(1,4)BENZOTHIAZIN-6-ONE; ESTROGEN RECEPTOR; RECOMBINANT PROTEIN; THIAZINE DERIVATIVE;

AGONIST; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG PURIFICATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ELECTRON MICROSCOPY; ESTROGEN ACTIVITY; HORMONE BINDING; MOUSE; NONHUMAN; PROTEIN DOMAIN; RECEPTOR DOWN REGULATION; TRANSCRIPTION REGULATION; CELL LINE; CHEMISTRY; DRUG POTENTIATION; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOASSAY;

CELL LINE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; RADIOLIGAND ASSAY; RECEPTORS, ESTROGEN; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THIAZINES;

EID: 10844224307     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.25.335     Document Type: Article

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