-
3
-
-
0001053316
-
Drugs and the treatment of psychiatic disorders
-
Goodman, A. G., Gilman L. S., Rall, T. W., Murad, F., Eds.; Macmillan: New York
-
Baldessarini, R. J. Drugs and the Treatment of Psychiatic Disorders. In The Pharmacological Basis of Therapeutics, 7th ed.; Goodman, A. G., Gilman L. S., Rall, T. W., Murad, F., Eds.; Macmillan: New York, 1985, p 416.
-
(1985)
The Pharmacological Basis of Therapeutics, 7th Ed.
, pp. 416
-
-
Baldessarini, R.J.1
-
6
-
-
0030982240
-
-
Bodkin J.A., Kasser R.A., Wines J.D., Gardner D.M., Baldessarini R.J. J. Clin. Psychiatry. 58:1997;137.
-
(1997)
J. Clin. Psychiatry
, vol.58
, pp. 137
-
-
Bodkin, J.A.1
Kasser, R.A.2
Wines, J.D.3
Gardner, D.M.4
Baldessarini, R.J.5
-
10
-
-
85031074553
-
-
i (nM): 5HT <5, DA<20 and NE<50. Catalyst™, version 4.5 (Accelerys, San Diego, CA, USA). Common feature approach generated within Catalyst, using BEST with an energy limit at 10 Kcal/mol, default dictionary definition, feature spacing set to 150 picometer with variable weight and tolerance.
-
-
-
-
11
-
-
0035837029
-
-
(a) Davies H.M.L., Kuhn L.A., Thornley C., Matasi J.J., Sexton T., Childers S.R. J. Med. Chem. 44:2001;1509.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 1509
-
-
Davies, H.M.L.1
Kuhn, L.A.2
Thornley, C.3
Matasi, J.J.4
Sexton, T.5
Childers, S.R.6
-
12
-
-
0029992705
-
-
(b) Davies H.M.L., Gilliat V., Kuhn L.A., Saikali E., Ren P., Hammand P.S., Sexton T., Childers S.R. J. Med. Chem. 39:1996;2554.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 2554
-
-
Davies, H.M.L.1
Gilliat, V.2
Kuhn, L.A.3
Saikali, E.4
Ren, P.5
Hammand, P.S.6
Sexton, T.7
Childers, S.R.8
-
13
-
-
0032701144
-
-
(c) Javanmard S., Deutsch H.M., Collard M.M., Kuhar M.J., Schweri M.M. J. Med. Chem. 42:1999;4836.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 4836
-
-
Javanmard, S.1
Deutsch, H.M.2
Collard, M.M.3
Kuhar, M.J.4
Schweri, M.M.5
-
15
-
-
85031078620
-
-
1H (ppm) δ 6.05 (d, 2H), 6.50 (d, 2H), ratio 79:21. The major isomer was confirmed as endo by nOe: interactions are observed between the bridgehead proton and the aromatic ring; such an interaction is not observed for the exo isomer.
-
-
-
-
16
-
-
85031070683
-
-
r (E2) 22.2 min. Analytical column size: 250×4.6 mm 1D and for preparative work: 250×20 mm 1D.
-
-
-
-
17
-
-
33748726159
-
-
(a) Evans D.A., Murry J.A., von Matt P., Norcross R.D., Miller S.J. Angew. Chem., Int. Ed. Engl. 34:1995;798.
-
(1995)
Angew. Chem., Int. Ed. Engl.
, vol.34
, pp. 798
-
-
Evans, D.A.1
Murry, J.A.2
Von Matt, P.3
Norcross, R.D.4
Miller, S.J.5
-
19
-
-
85031080583
-
-
r (E2) 40.89 min. Absolute stereochemistry not assigned. Absolute stereochemistry was assigned later by X-ray crystallographic analysis of Ar=naphthyl, 16 d.
-
-
-
-
22
-
-
85031081276
-
-
r (E2) 15.21 min.
-
-
-
-
23
-
-
85031072675
-
-
2NH) HPLC/MS profiling.
-
-
-
-
27
-
-
0031434059
-
-
Agoston G.E., Wu J.H., Izenwasser S., George C., Kline R.H., Hauck Newman A. J. Med. Chem. 40:1997;4329.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 4329
-
-
Agoston, G.E.1
Wu, J.H.2
Izenwasser, S.3
George, C.4
Kline, R.H.5
Hauck Newman, A.6
-
28
-
-
0041951369
-
-
(a) Peuch A.J., Chermant R., Poncelet M., Doare L., Simon P. Psychopharmacology. 75:1981;84.
-
(1981)
Psychopharmacology
, vol.75
, pp. 84
-
-
Peuch, A.J.1
Chermant, R.2
Poncelet, M.3
Doare, L.4
Simon, P.5
|