Portal hypertension: Return to fetal life to re-attempt differentiation?

Medical Hypotheses

Volumn 62, Issue 1, 2004, Pages 79-81

  Aller, M A ^a   Lopez L ^b   Nava, M P ^a   Arias, J L ^b   Duran H J ^a   Arias, J ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF OVIEDO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; CYTOCHROME C OXIDASE; CYTOKINE; SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CHORION VILLUS; CHRONIC LIVER DISEASE; DEVELOPMENTAL STAGE; DISEASE PREDISPOSITION; DUODENUM; ENTEROPATHY; ENZYME ACTIVITY; FETUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; ILEUM; IMMUNE RESPONSE; IMMUNITY; INFERIOR CAVA VEIN; INTESTINE; INTESTINE CELL; JEJUNUM; LIVER CIRRHOSIS; MAST CELL; MORPHOLOGY; NECROTIZING ENTEROCOLITIS; NONHUMAN; PATHOGENESIS; PERINATAL PERIOD; PHENOTYPE; PLACENTA; PORTAL HYPERTENSION; PORTAL VEIN; PRENATAL PERIOD; PRIORITY JOURNAL; SPLANCHNIC NERVE; STEM CELL; STRESS; SYSTEMIC CIRCULATION; TISSUE METABOLISM;

EID: 10744233057     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(03)00275-5     Document Type: Article

References (18)

1. Mahl TC, Groszmann RJ. Pathophysiology of portal hypertension and variceal bleeding. Surg Clin North Am 1990;70:251-66.
2. Dawson JL. Normal anatomy. In: Wright R, Alberti KGMM, Karran S, Millward-Sadler GH, editors. Liver and biliary disease: pathophysiology diagnosis management. London: WB Saunders; 1979. p. 3-12.
3. Sherlock S. The portal venous system and portal hypertension. In: Sherlock S, editor. Diseases of the liver and biliary system. 8th ed. Oxford: Blackwell; 1989. p. 151-207.
4. Whipple AO. The problems of portal hypertension in relation to hepatosplenopathies. Ann Surg 1945;122: 449-75.
5. Bosch J, Pizcueta P, Feu F, et al. Pathophysiology of portal hypertension. Gastroenterol Clin North Am 1992;21:1-14.
6. Jonas G, Erilckson RA, Morgan T. Effect of portal hypertension on In vivo bile acid-mediated small intestinal mucosal injury in the rat. Dig Dis Sci 1990;35:743-8.
7. López L, González-Pardo H, et al. Cytochrome oxidase activity in splanchnic organs of portal hypertensive rats. Rev Esp Enferm Dig 2001;93:794-9.
8. Nanthakumar NN, Fusunyan RD, Sanderson I, et al. Inflammation in the developing human intestine: a possible pathophysiologic contribution to necrotizing enterocolitis. PNAS 2000;97:6043-8.
9. Holt PG, Jones CA. The development of the immune system during pregnancy and early life. Allergy 2000;55:688-97.
10. Romagnani S. T-cell subsets (Th1 versus Th2). Ann Allergy Asthma Immunol 2000;85:9-21.
11. Diez-Arias JA, Aller MA, et al. Increased duodenal mucosa infiltration by mast cells in rats with portal hypertension. Dig Surg 2001;18:34-40.
12. Romagnani S. The Th17Th2 paradigm. Immunol Today 1997;18:263-6.
13. Castilla-Cortazar I, Prieto J, et al. Impaired intestinal sugar transport in cirrhotic rats: correction by low doses of insulin-like growth factor I. Gastroenterology 1997;113: 1180-7.
14. Castilla-Cortazar I, García M, et al. Insulin-like growth factor-I reverts testicular atrophy in rats with advanced cirrhosis. Hepatology 2000;31:592-600.
15. Carey HV, Mangino HJ, Southard JH. Changes in gut function during hibernation: implications for bowel transplantation and surgery. Gut 2001;49: 459-61.
16. 4 levels in short-term prehepatic portal hypertension in rats. Dig Dis Sci 2000;45:1865-71.
17. Schaeffer C, Diab-Assef M, et al. Cytokine gene expression during postnatal small intestine development: regulation by glucocorticoids. Gut 2000;47: 192-9.
18. Mayer EA. The neurobiology of stress and gastrointestinal disease. Gut 2000;47:861-9.