Determination and use of haplotypes: Ethnic comparison and association of the lipoprotein lipase gene and coronary arter disease in Mexican-Americans

Genetics in Medicine

Volumn 5, Issue 4, 2003, Pages 322-327

  Goodarzi, Mark O ^a,b,d   Guo, Xiuqing ^a,d   Taylor, Kent D ^a,d   Quiñones, Manuel J ^b   Samayoa, Carlos ^a,d   Yang, Huiying ^a,d   Saad, Mohammad F ^b   Palotie, Aarno ^b   Krauss, Ronald M ^c   Hsueh, Willa A ^b   Rotter, Jerome I ^a,d  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Coronary artery disease; Haplotype; Lipoprotein lipase; Mexican American; Single nucleotide polymorphism

Indexed keywords

LIPOPROTEIN LIPASE;

ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ETHNIC GROUP; FEMALE; GENE ACTIVITY; GENE FREQUENCY; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HOMOZYGOSITY; HUMAN; MALE; MEXICO; NUCLEOTIDE SEQUENCE; POPULATION GENETICS; SCREENING TEST; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED STATES;

ALLELES; CORONARY ARTERIOSCLEROSIS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HISPANIC AMERICANS; HOMOZYGOTE; HUMANS; LIPOPROTEIN LIPASE; LOGISTIC MODELS; MEXICAN AMERICANS; POLYMORPHISM, GENETIC;

EID: 10744230741     PISSN: 10983600     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.GIM.0000076971.55421.AD     Document Type: Article

References (17)

1. Daly MJ, Rioux JD, Schaffner SF, Hudson TJ, Lander ES. High-resolution haplotype structure in the human genome. Nat Genet 2001;29:229-232.
2. Rioux JD, Daly MJ, Silverberg MS, Lindblad K, Steinhart H, Cohen Z et al. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat Genet 2001;29:223-228.
3. Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B et al. The structure of haplotype blocks in the human genome. Science 2002;296:2225-2229.
4. Templeton AR, Sing CF, Kessling A, Humphries S. A cladistic analysis of phenotype associations with haplotypes inferred from restriction endonuclease mapping. II. The analysis of natural populations. Genetics 1988;120:1145-1154.
5. Templeton AR. Cladistic approaches to identifying determinants of variability in multifactorial phenotypes and the evolutionary significance of variations in the human genome. Ciba Found Symp 1996;197:259-277.
6. Murthy V, Julien P, Gagne C. Molecular pathobiology of the human lipoprotein lipase gene. Pharmacol Ther 1996;70:101-135.
7. Wu DA, Bu X, Warden CH, Shen DD, Jeng CY, Sheu WH et al. Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22. J Clin Invest 1996;97:2111-2118.
8. Ahn YI, Ferrell RE, Hamman RF, Kamboh MI. Association of lipoprotein lipase gene variation with the physiological components of the insulin-resistance syndrome in the population of the San Luis Valley, Colorado. Diabetes Care 1993;16:1502-1506.
9. Lee WJ, Sheu WH, Jeng CY, Young MS, Chen YT. Associations between lipoprotein lipase gene polymorphisms and insulin resistance in coronary heart disease. Chung-Hua I Hsueh Tsa Chih [Chinese Medical Journal] 2000;63:563-572.
10. Humphries SE, Nicaud V, Margalef J, Tiret L, Talmud PJ. Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides: The European Atherosclerosis Research Study (EARS). Arterioscler Thromb Vasc Biol 1998;18:526-534.
11. Templeton AR, Clark AG, Weiss KM, Nickerson DA, Boerwinkle E, Sing CF. Recombinational and mutational hotspots within the human lipoprotein lipase gene. Am J Hum Genet 2000;66:69-83.
12. Nickerson DA, Taylor SL, Weiss KM, Clark AG, Hutchinson RG, Stengård J et al. DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene. Nat Genet 1998;19:233-240.
13. Livak KJ. Allelic discrimination using fluorogeneic probes and the 5′ nuclease assay. Genet Anal 1999;14:143-149.
14. Sobel E, Lange K. Descent graphs in pedigree analysis: Applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet 1996;58:1323-1337.
15. SAS [Computer Program]. Release 8.0. Caryn, NC: SAS Institute, 1999.
16. Templeton AR, Weiss KM, Nickerson DA, Boerwinkle E, Sing CF. Cladistic structure within the human lipoprotein lipase genes and its implications for phenotypic association studies. Genetics 2000;156:1259-1275.
17. Nicklas BJ, Ferrell RE, Rogus EM, Berman DM, Ryan AS, Dennis KE et al. Lipoprotein lipase gene variation is associated with adipose tissue lipoprotein lipase activity, and lipoprotein lipids and glucose concentrations in overweight postmenopausal women. Hum Genet 2000;106:420-424.