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Volumn 13, Issue 19, 2003, Pages 3341-3344

Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; PHENYLALANINE DERIVATIVE;

EID: 10744225910     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00670-X     Document Type: Article
Times cited : (21)

References (22)
  • 8
    • 0034815528 scopus 로고    scopus 로고
    • (b) HCV RNA-dependent RNA polymerase as a target for antiviral development: (i) Lai M.M.C. Antiviral Chem. Chemother. 12:2001;143. (ii) Walker, M. P.; Hong, Z. Curr. Opin. Pharm. 2002, 2, 1471.
    • (2001) Antiviral Chem. Chemother. , vol.12 , pp. 143
    • Lai, M.M.C.1
  • 9
    • 0042393492 scopus 로고    scopus 로고
    • (b) HCV RNA-dependent RNA polymerase as a target for antiviral development: (i) Lai M.M.C. Antiviral Chem. Chemother. 12:2001;143. (ii) Walker, M. P.; Hong, Z. Curr. Opin. Pharm. 2002, 2, 1471.
    • (2002) Curr. Opin. Pharm. , vol.2 , pp. 1471
    • Walker, M.P.1    Hong, Z.2
  • 11
    • 0000885084 scopus 로고    scopus 로고
    • (a) For a review on recent patent literature, see: Zhang X. Idrugs. 5:2002;154.
    • (2002) Idrugs , vol.5 , pp. 154
    • Zhang, X.1
  • 13
    • 85031068693 scopus 로고    scopus 로고
    • note
    • Information reported in Iddb3 from Current Drugs Ltd.
  • 19
    • 85031078660 scopus 로고    scopus 로고
    • note
    • 1H NMR spectra of test compounds also indicated the presence of numerous rotamers.
  • 21
    • 85031076916 scopus 로고    scopus 로고
    • note
    • 2-Ethyl-4-chlorobenzoic acid was prepared from methyl 2-bromo-4-chlorobenzoic acid via a three step sequence employing vinyl Stille coupling, hydrogenation, and hydrolysis.
  • 22
    • 0035114683 scopus 로고    scopus 로고
    • FlashPlate™ scintillation proximity assays for characterization and screening of DNA polymerase, primase, and helicase activities
    • 50 value of a positive internal control was within standard deviation range.
    • (2001) J. Biomol. Screen , vol.6 , pp. 39
    • Earnshaw, D.L.1    Pope, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.