Systolic blood pressure variability as a risk factor for stroke and cardiovascular mortality in the elderly hypertensive population

Journal of Hypertension

Volumn 21, Issue 12, 2003, Pages 2251-2257

  Pringle, Edward ^a   Phillips, Charles ^a   Thijs, Lutgarde ^b   Davidson, Christopher ^a   Staessen, Jan A ^b   De Leeuw, Peter W ^c   Jaaskivi, Matti ^d   Nachev, Choudomir ^e   Parati, Gianfranco ^f   O'Brien, Eoin T ^g   Tuomilehto, Jaakko ^h   Webster, John ⁱ   Bulpitt, Christopher J ^j   Fagard, Robert H ^b  

^a ROYAL SUSSEX COUNTY HOSPITAL   (United Kingdom)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^d Tikkurilan Sosiaali ja Terveyskeskus   (Finland)

^e St Ann Hospital   (Bulgaria)

^f ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^g BEAUMONT HOSPITAL   (Ireland)

^h Dept of Epidemiol and Hlth Prom ^*  (Finland)

ⁱ ABERDEEN ROYAL INFIRMARY   (United Kingdom)

^j HAMMERSMITH HOSPITAL   (United Kingdom)

more..

Author keywords

Ambulatory monitoring; Blood pressure variability; Elderly; Isolated systolic hypertension; Prognosis

Indexed keywords

ANTIHYPERTENSIVE AGENT; ENALAPRIL; HYDROCHLOROTHIAZIDE; NITRENDIPINE;

ADULT; AGED; AGING; AORTA DISSECTION; ARTICLE; BLOOD PRESSURE MONITORING; CARDIOVASCULAR RISK; CIRCADIAN RHYTHM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; HEART FAILURE; HEART INFARCTION; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MORTALITY; PERIPHERAL VASCULAR DISEASE; PREDICTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; STROKE; SUDDEN DEATH; SYSTOLIC BLOOD PRESSURE; SYSTOLIC HYPERTENSION; TREATMENT OUTCOME;

EID: 10744225316     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200312000-00012     Document Type: Article

References (25)

1. Kannel WB, Wolf PA, McGee DL, Dawber TR, McNamara P, Castelli WP. Systolic blood pressure, arterial rigidity, and the risk of stroke: the Framingham study. JAMA 1981; 245:1225-1229.
2. Liu L, Wang JG, Gong L, Liu G, Staessen JA. Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension. Systolic Hypertension in China (Syst-China) Collaborative Group. J Hypertens 1998; 16:1823-1829.
3. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991; 265:3255-3264.
4. Staessen JA, Fagard R, Thijs L, Celis H, Arabidze GG, Birkenhager WH, et al. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet 1997; 350:757-764.
5. Staessen JA, Thijs L, Birkenhager WH, Bulpitt CJ, Fagard R. Update on the Systolic Hypertension in Europe (Syst-Eur) Trial. Hypertension 1999; 33:1476-1477.
6. Parati G, Pomidossi G, Albini F, Malaspina D, Mancia G. Relationship of 24-hour blood pressure mean and variability to severity of target-organ damage in hypertension. J Hypertens 1987; 5:93-98.
7. Frattola A, Parati G, Cuspidi C, Albini F, Mancia G. Prognostic value of 24-hour blood pressure variability. J Hypertens 1993; 11:1133-1137.
8. Emelianov D, Thijs L, Staessen JA, Celis H, Clement D, Davidson C, et al. Conventional and ambulatory measurements of blood pressure in old patients with isolated systolic hypertension: baseline observations in the Syst-Eur trial. Blood Press Monit 1998; 3:173-180.
9. Staessen JA, Thijs L, Fagard R, O'Brien ET, Clement D, de Leeuw PW, et al. Predicting cardiovascular risk using conventional versus ambulatory blood pressure in older patients with systolic hypertension. JAMA 1999; 282:539-546.
10. Perloff D, Sokolow M, Cowan R. The prognostic value of ambulatory blood pressures. JAMA 1983; 249:2792-2798.
11. Perloff D, Sokolow M, Cowan RM, Juster RP. Prognostic value of ambulatory blood pressure measurements: further analyses. J Hypertens 1989; 7(suppl 3):s3-s10.
12. Verdecchia P, Schillaci G, Borgioni C, Ciucci A, Porcellati C. Prognostic significance of the white coat effect. Hypertension 1997; 29: 1218-1224.
13. Amery A, Birkenhager W, Bulpitt CJ, Clement D, de Leeuw P, Dollery CT, et al. Syst-Eur: a multicentre trial on the treatment of isolated systolic hypertension in the elderly: objectives, protocol, and organisation. Aging Clin Exp Res 1991; 3:287-302.
14. Staessen JA, Amery A, Clement D, Cox J, de Cort P, Fagard R, et al. Twenty-four hour blood pressure monitoring in Syst-Eur trial. Aging Clin Exp Res 1992; 4:85-91.
15. Staessen JA, Fagard R, Thijs L, Celis H, Birkenhager WH, Bulpitt CJ, et al. Subgroup and per-protocol analysis of the randomised european trial on isolated systolic hypertension in the elderly. Arch Intern Med 1998; 158:1681-1691.
16. Kikuya M, Hozawa A, Ohokubo T, Tsuji I, Michimata M, Matsubara M, et al. Prognostic significance of blood pressure and heart rate variabilities. Hypertension 2000; 36:901-906.
17. Pickering TG, James GD. Ambulatory blood pressure and prognosis. J Hypertens 1994; 12(suppl 8):S29-S33.
18. Leary AC, Donnan PT, MacDonald TM, Murphy MB. The influence of physical activity on the variability of ambulatory blood pressure. Am J Hypertens 2000; 13:1067-1073.
19. Goldstein IB, Bartzokis G, Hance DB, Sapiro D. Relationship between blood pressure and subcortical lesion in healthy elderly people. Stroke 1998; 29:765-772.
20. Kukla C, Sander D, Schwarze J, Wittich I, Klingelhofer J. Changes of Circadian blood pressure patterns are associated with the occurrence of lacunar infarction. Arch Neurol 1998; 55:683-688.
21. Imai Y, Aihara A, Ohkubo T, Nagai K, Tsuji I, Minami N, et al. Factors that affect blood pressure variability. Am J Hypertens 1997; 10:1281-1289.
22. Schwartz GL, Turner ST, Moore JH, Sing CF. Effect of time of day on intraindividual variability in ambulatory blood pressure. Am J Hypertens 2000; 13:1203-1209.
23. Mancia G, Omboni S, Ravogli A, Parati G, Zanchetti A. Ambulatory blood pressure monitoring in the evaluation of antihypertensive treatment: Additional information from a large database. Blood Press 1995; 4: 148-156.
24. Mancia G, Grassi G. Mechanisms and clinical implications of blood pressure variability. J Cardiovasc Pharmacol 2000; 35(suppl 4): S15-S19.
25. Parati G, Frattola A, Di Rienzo M, Castiglioni P, Pedotti A, Mancia G. Effects of aging on 24-h dynamic baroreceptor control of heart rate in ambulant subjects. Am J Physiol 1995; 268:H1606-H1612.