Safety of contrast-enhanced MR angiography employing gadobutrol 1.0 M as contrast material

European Radiology

Volumn 13, Issue 9, 2003, Pages 2067-2074

  Balzer, Jörn O ^a   Loewe, Christian ^b   Davis, Kirsten ^a   Goyen, Mathias ^c   Leiner, Tim ^d   Meaney, James F M ^e   Pöckler Schöniger, Christiane ^f   Schulte Altedorneburg, Gernot ^g   Tombach, Bernd ^h   Vosshenrich, Rolf ⁱ   Wegener, Robin ^j  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY HOSPITAL ESSEN   (Germany)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^e LEEDS GENERAL INFIRMARY   (United Kingdom)

^f UNIVERSITY OF HEIDELBERG   (Germany)

^g Klin F Diagnostische Radiol N   (Germany)

^h UNIVERSITY OF MÜNSTER   (Germany)

ⁱ UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^j BAYER PHARMA AG   (Germany)

more..

Author keywords

Contrast enhanced MR angiography; Gadobutrol; Peripheral artery; Safety study; Side effects

Indexed keywords

GADOBUTROL; GADOLINIUM CHELATE; GADOLINIUM PENTETATE MEGLUMINE; GADOTERIDOL; IODINATED CONTRAST MEDIUM; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT;

ADULT; AGED; ARTERY DISEASE; ARTICLE; ATRIOVENTRICULAR BLOCK; BLOOD PRESSURE; BLOOD SAMPLING; BOLUS INJECTION; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CENTRAL NERVOUS SYSTEM DISEASE; CLINICAL TRIAL; CONTRAST ENHANCEMENT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DEPRESSION; DIARRHEA; DOSE RESPONSE; DRUG EFFICACY; DRUG EXCRETION; DRUG SAFETY; DRUG TOLERABILITY; DRY EYE; DYSPEPSIA; DYSPNEA; ECG ABNORMALITY; ELECTROCARDIOGRAM; FEMALE; HEADACHE; HEART ATRIUM FIBRILLATION; HEART MUSCLE CONDUCTION SYSTEM; HEART RATE; HEART VENTRICLE EXTRASYSTOLE; HUMAN; HYPERTENSION; INJURY; LEG EDEMA; MAGNETIC RESONANCE ANGIOGRAPHY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; PAIN; PARESTHESIA; PRIORITY JOURNAL; PRURITUS; SIDE EFFECT; SINUS BRADYCARDIA; SUPRAVENTRICULAR PREMATURE BEAT; SYNCOPE; TACHYCARDIA; TASTE DISORDER; URINALYSIS; VASODILATATION; VERTIGO;

ADULT; AGED; BLOOD PRESSURE; CONTRAST MEDIA; CREATININE; ELECTROCARDIOGRAPHY; FEMALE; HEART RATE; HUMANS; INJECTIONS, INTRAVENOUS; MAGNETIC RESONANCE ANGIOGRAPHY; MIDDLE AGED; ORGANOMETALLIC COMPOUNDS; VASCULAR DISEASES; ZINC;

EID: 10744225263     PISSN: 09387994     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00330-002-1768-5     Document Type: Article

References (19)

1. Niendorf HP, Alhassan A, Balzer T, Clauss W, Geens V (1994) Safety and risk of gadolinium-DTPA: extended clinical experience after more than 20 million applications. Invest Radiol 29 (Suppl 2):179-182
2. Tweedle MF, Hagan JJ, Kumar K, Mantha S, Chang CA (1991) Reaction of gadolinium chelates with endogenously available ions. Magn Reson Imaging 9:409-415
3. Prince MR, Narasimham DL, Stanley JC, Chenevert TL, Williams DM, Marx MV, Cho KJ (1995) Breath-hold gadolinium-enhanced MRA of the abdominal aorta and its major branches. Radiology 197:785-792
4. Holland GA, Dougherty L, Carpenter JP, Golden MA, Gilfeather M, Slossman F, Schnall MD, Axel L (1996) Breath-hold ultrafast 3D gadolinium-enhanced MRA of the aorta and the renal and other visceral abdominal arteries. Am J Roentgenol 166:971-981
5. Prince MR (1996) Body MRA with gadolinium contrast agents. Magn Reson Imaging Clin North Am 4:11-24
6. Mitsuzaki K, Yamashita Y, Ogata I, Tang Y, Namimoto T, Takahashi M (1999) Optimal protocol for injection of contrast material at MRA: study of healthy volunteers. Radiology 213:913-918
7. Fellner F, Janka R, Dobritz M, Lenz M, Lang W, Bautz W (1999) Gd-BOPTA: The MRA contrast agent of choice? Röntgenpraxis 52:51-58
8. Knopp MV, Floemer F, Schoenberg SO, Bock M, Tengg Kobligk H von, Hentrich R, Lodemann K, Kaick G von (1999) Does a weakly binding Gd-chelate improve MR angiography? Initial findings using Gd-BOPTA for multiphasic 3D MRA. Proc Int Soc Magn Reson Med 7:1208
9. Leung DA, Hany TF, Debatin JF (1998) Three-dimensional contrast-enhanced magnetic resonance angiography of the abdominal arterial system. Cardiovasc Intervent Radiol 21:1-10
10. Schoenberg S, Bock M, Knopp MV, Essig M, Laub G, Hawighorst H, Zuna I, Kallinowski F, Kaick G von (1999) Renal arteries: optimization of three-dimensional gadolinium-enhanced MR angiography with bolus-timing-independent fast multiphase acquisition in a single breath hold. Radiology 211:667-679
11. Tombach B, Heindel W (2002) Value of 1.0 M gadolinium chelates: review of preclinical and clinical data on gadobutrol. Eur Radiol 12:1550-1556
12. Priebe M, Mohr A, Brossmann J, Heller M, Fraham C (2002) Gadobutrol: an alternative contrast agent for digital subtraction dacryocystography. Eur Radiol 12:2083-2086
13. Runge VM, Parker JR (1997) Worldwide clinical assessment of gadoteridol injection: an update. Eur Radiol 7 (Suppl 5):243-245
14. Nelson KL, Gifford LM, Lauber-Huber C, Gross CA, Lasser TA (1995) Clinical safety of gadopentetate dimeglumine. Radiology 196:439-443
15. Puttagunta NR, Gibby WA, Puttagunta VL (1996) Comparative transmettallation kinetics and thermodynamic stability of gadolinium-DTPA bis-glucosamide and other magnetic resonance imaging contrast media. Invest Radiol 31:619-624
16. Corot C, Idee JM, Hentsch AM, Santus R, Mallet C, Goulas V, Bonnemain B, Meyer D (1998) Structure-activity relationship of macrocyclic and linear gadolinium chelates: investigation of transmetallation effect on the zinc-dependent metallopeptidase angiotensin-converting enzyme. J Magn Reson Imaging 8:695-702
17. Puttagunta NR, Gibby WA, Smith GT (1996) Human in vivo comparative study of zinc and copper transmetallation after administration of magnetic resonance imaging contrast agents. Invest Radiol 12:739-742
18. Tombach B, Bremer C, Reimer P, Kisters K, Schaefer RM, Geens V, Heindel W (2001) Renal tolerance of a neutral Gadolinium chelate (gadobutrol) in patients with chronic renal failure: results of a randomized study. Radiology 218:651-657
19. Prince MR, Arnoldus C, Frisoli JK (1996) Nephrotoxicity of high dose gadolinium compared with iodinated contrast. J Magn Reson Imaging 1:162-166