Conspicuous GTG-banding results of the centromere-near region can be caused by alphoid DNA heteromorphism [3]

Clinical Genetics

Volumn 64, Issue 2, 2003, Pages 166-167

  Liehr, Thomas ^a   Ziegler, M ^b   Starke, H ^b   Heller, A ^b   Kuechler, A ^b   Kittner, G ^b   Beensen, V ^b   Seidel, J ^b   Hassler H ^b   Musebeck J ^b   Claussen, U ^b  

^a Institut fur Humangenetik und Anthroplogie   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; SATELLITE DNA;

ADULT; CASE REPORT; CENTROMERE; CHROMOSOME 13P; CHROMOSOME 13Q; CHROMOSOME 15; CHROMOSOME 22Q; CHROMOSOME 4; CHROMOSOME 4P; CHROMOSOME 4Q; CHROMOSOME ANALYSIS; CHROMOSOME BANDING PATTERN; CHROMOSOME DELETION; CHROMOSOME DUPLICATION; CHROMOSOME PAINTING; CHROMOSOME SATELLITE; DIAGNOSTIC PROCEDURE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC POLYMORPHISM; GENETICS; GROWTH RETARDATION; HUMAN; HUMAN CELL; KARYOTYPE; LETTER; MALE; METHODOLOGY; MOLECULAR PROBE; NEWBORN; PATIENT REFERRAL; PERICENTRIC CHROMOSOME INVERSION; PRIORITY JOURNAL; SCHOOL CHILD; SUBFERTILITY; TURNER SYNDROME;

CENTROMERE; CHROMOSOME BANDING; DNA, SATELLITE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MOLECULAR DIAGNOSTIC TECHNIQUES;

EID: 10744222332     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0004.2003.00114.x     Document Type: Letter

References (12)

1. Verma RS, Batish SD, Gogineni SK, Kleyman SM, Stetka DG. Centromeric alphoid DNA heteromorphisms of chromosome 21 as revealed by FISH-technique. Clin Genet 1997: 51: 91-93.
2. Liehr T, Pfeiffer RA, Trautmann U, Gebhart E. Centromeric alphoid DNA heteromorphisms of chromosome 22 as revealed by FISH-technique. Clin Genet 1998: 53: 231-232.
3. Verma RS, Ishwar L, Gogineni SK, Kleyman SM. Pericentromeric heteromorphism of human chromosome 18 as revealed by FISH-technique. Ann Genet 1998: 41: 154-156.
4. Duval A, Feneux D, Sutton L, Tchernia G, Leonard C. Spurious monosomy 7 in leukemia due to centromeric heteromorphism. Cancer Genet Cytogenet 2000: 119: 67-69.
5. Skinner JI, Govberg IJ, DePalma RT, Cotter PD. Heteromorphisms of chromosome 18 can obscure detection of fetal aneuploidy by interphase FISH. Prenat Diagn 2001: 21: 702-703.
6. Liehr T, Schreyer I, Neumann A et al. Two more possible pitfalls of rapid prenatal diagnostics using interphase nuclei. Prenat Diagn 22(6): 497-499.
7. Lin MS, Zhang A, Fujimoto A, Wilson MG. A rare 6q11+ heteromorphism: cytogenetic analysis and in situ hybridization. Hum Hered 1994: 44: 31-36.
8. Romain DR, Whyte S, Callen DF, Eyre HJ. A rare heteromorphism of chromosome 20 and reproductive loss. J Med Genet 1991: 28: 477-478.
9. Fineman RM, Issa B, Weinblatt V. Prenatal diagnosis of a large heteromorphic region in a chromosome 5: implications for genetic counseling. Am J Med Genet 1989: 32: 498-499.
10. Crossen PE. Variation in the centromeric banding of chromosome 19. Clin Genet 1975: 8: 218-222.
11. Beverstock GC, Klumper F, Helderman VD, Enden AT. Yet another variation on the theme of chromosome 18 heteromorphisms? Prenat Diagn 1997: 17: 585-586.
12. Riordan D, Dawson AJ. The evaluation of 15q proximal duplications by FISH. Clin Genet 1998: 54: 517-521.