Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase

Journal of Molecular Biology

Volumn 337, Issue 2, 2004, Pages 387-398

  Hartley, Andrew ^a   Glynn, Steven E ^a   Barynin, Vladimir ^a   Baker, Patrick J ^a   Sedelnikova, Svetlana E ^a   Verhees, Corné ^b   De Geus, Daniel ^b   Van Der Oost, John ^b   Timson, David J ^c   Reece, Richard J ^d   Rice, David W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

FA, structure factor amplitudes for the anomalous scatterers; Galactokinase deficiency; GalK, galactokinase; GHMP kinase superfamily; Pyrococcus furiosus; X ray crystallography

Indexed keywords

ADENOSINE TRIPHOSPHATE MAGNESIUM; BACTERIAL ENZYME; GALACTOKINASE; GALACTOSE;

AMINO ACID SEQUENCE; ARTICLE; CARBOHYDRATE METABOLISM; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; GALACTOSEMIA; GENE CLUSTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PYROCOCCUS FURIOSUS; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION; YEAST;

PYROCOCCUS; PYROCOCCUS FURIOSUS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 10744221600     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.01.043     Document Type: Article

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