Pharmacologic pre-conditioning and controlled reperfusion prevent ischemia-reperfusion injury after 30 minutes of hypoxia/ischemia in porcine hearts

Journal of Heart and Lung Transplantation

Volumn 22, Issue 11, 2003, Pages 1234-1244

  Fedalen, P A ^a   Piacentino III, V ^a   Jeevanandam, V ^a,b   Fisher, C ^a   Greene, J ^a   Margulies, K B ^a   Houser, S R ^a   Furukawa, S ^a   Singhal, A K ^a   Goldman, B I ^a,c  

^a Temple University Health Sciences Center   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARIPORIDE; NORADRENALIN; PHOSPHOTRANSFERASE; SCAVENGER; SODIUM PROTON EXCHANGE PROTEIN;

ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HEART BEAT; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART SURGERY; HISTOPATHOLOGY; HYPOXIA; LEUKOPENIA; MALE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY;

EID: 10744221596     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1053-2498(02)01237-8     Document Type: Article

References (28)

1. Alexander J.W., Zola J.C. Expanding the donor pool use of marginal donors for solid organ transplantation. Clin Transplant. 10:1996;1-19.
2. Kron I.L., Tribble C.G., Kern J.A., et al. Successful transplantation of marginally acceptable thoracic organs. Ann Surg. 215:1993;518-522.
3. Boucek M.M., Mathis C.M., Kanakriyeh M.S., et al. Donor shortage use of the dysfunctional donor heart. J Heart Lung Transplant. 12:(suppl):1993;S186- 190.
4. Hosenpud J.D., Bennett L.E., Keck B.M., Boucek M.M., Novick R.J. The Registry of the International Society for Heart and Lung Transplantation eighteenth annual report - 2001. J Heart Lung Transplant. 20:2001;805-815.
5. Laskowski I.A., Pratschke J., Wilhelm M.J., Paz D., Tilney N.L. Non-heartbeating kidney donors. Clin Transplant. 13:1999;281-286.
6. Vinten-Johansen J., Thourani V.H., Ronson R.S., et al. Broad-spectrum cardioprotection with adenosine. Ann Thorac Surg. 68:1999;1942-1948.
7. Hartmann M., Decking U.K. Blocking Na(+)-H+ exchange by cariporide reduces Na(+)-overload in ischemia and is cardioprotective. J Mol Cell Cardiol. 31:1999;1985-1995.
8. Ludlow J.W. Interactions between SV40 large tumor antigen and the growth suppressor proteins pRB and p53. FASEB J. 7:1993;866-871.
9. Jahania M.S., Sanchez J.A., Narayan P., Lasley R.D., Mentzer R.M. Jr. Heart preservation for transplantation principles and strategies. Ann Thor Surg. 68:1999;1983-1987.
10. Vargas S.O., Sampson B.A., Schoen F.J. Pathologic detection of early myocardial infarction a critical review of the evolution and usefulness of modern techniques. Modern Pathol. 12:1999;635-645.
11. Gundry S.R., Alonso de Begona J., Kawauchi M., Liu H., Razzouk A.J., Bailey L.L. Transplantation and reanimation of hearts removed from donors 30 minutes after warm, asystolic 'death'. Arch Surg. 128:1993;989-991.
12. Takagaki M., Hisamochi K., Morimoto T., Bando K., Sano S., Shimizu N. Successful transplantation of cadaver hearts harvested one hour after hypoxic cardiac arrest. J Heart Lung Transplant. 15:1995;527-531.
13. Ferrera R., Marcscek P., Buidollet J., Berthet C., Dureau G. Lack of successful reanimation of pig hearts harvested more than 10 minutes after death. J Heart Lung Transplant. 14:1995;322-328.
14. Bolli R., Marban E. Molecular and cellular mechanisms of myocardial stunning. Physiol Rev. 79:1999;609-634.
15. Kloner R.A., Bolli R., Marban E., Reinlib L., Braunwald E. Medical and cellular implications of stunning, hibernation, and preconditioning an NHLBI workshop. Circulation. 97:1998;1848-1867.
16. Karmazyn M. The role of the myocardial sodium-hydrogen exchanger in mediating ischemic and reperfusion injury. From amiloride to cariporide. Ann NY Acad Sci. 874:1999;326-334.
17. Hale S.L., Kloner R.A. Effect of combined K(ATP) channel activation and Na(+)/H(+) exchange inhibition on infarct size in rabbits. Am J Physiol Heart Circ Physiol. 279:2000;H2673-2677.
18. Beavo J.A., Rogers M.L., Crofford O.B., Hardman J.G., Sutherland E.W., Newman E.V. Effects of xanthine derivatives on lipolysis and on adenosine 3′5′ monophosphate phosphodiesterase activity. Molec Pharmacol. 6:1970;597-603.
19. Bittner H.B., Kendall S.W., Chen E.P., Van Trigt P. Endocrine changes and metabolic responses in a validated canine brain death model. J Crit Care. 10:1995;56-63.
20. Rose A.G., Novitzky D., Factor S.M. Catecholamine-associated smooth muscle contraction bands in the media of coronary arteries of brain-dead baboons. Am J Cardiovasc Pathol. 2:1988;63-67.
21. Chen Z., Friedrich G.A., Soriano P. Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice. Genes Devel. 8:1994;2293-2301.
22. Jennings R.B., Hawkins H.K., Lowe J.E., et al. Relation between high energy phosphate and lethal injury in myocardial ischemia in the dog. Am J Pathol. 92:1978;187-214.
23. Hattori R., Otani H., Moriguchi Y., et al. NHE and ICAM-1 expression in hypoxic/reoxygenated coronary microvascular endothelial cells. Am J Physiol Heart Circ Physiol. 280:2001;H2796-2803.
24. White F.C., McKirnan M.D., Breisch E.A., Guth B.D., Liu Y.M., Bloor C.M. Adaptation of the left ventricle to exercise-induced hypertrophy. J Appl Physiol. 62:1987;1097-1110.
25. Non-heart-beating organ transplantationpractice and protocols. 2002;22 National Academy Press, Washington, DC.
26. Non-heart-beating organ transplantationmedical and ethical issues in procurement. 1997;46 National Academy Press, Washington, DC.
27. Hassanein W.H., Zellos L., Tyrrell T.A., et al. Continuous perfusion of donor hearts in the beating state extends preservation time and improves recovery of function. J Thorac Cardiovasc Surg. 116:1998;821-830.
28. Palazzo A.J., Jones S.P., Girod W.G., Anderson D.C., Granger D.N., Lefer D.J. Myocardial ischemia-reperfusion injury in CD18- and ICAM-1-deficient mice. Am J Physiol. 275:1998;H2300-2307.