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Volumn 206, Issue 21, 2003, Pages 3789-3802

Utilization of genomic sequence information to develop malaria vaccines

Author keywords

Genomics; Molecular immunology, immune screening, multi epitope; P. falciparum; Plasmodium; Proteomics; Vaccine

Indexed keywords

ANIMALS; ANTIGENS, PROTOZOAN; EPITOPES; GENE EXPRESSION; GENOME, PROTOZOAN; MALARIA VACCINES; MODELS, IMMUNOLOGICAL; OPEN READING FRAMES; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PROTEIN ARRAY ANALYSIS; VACCINES, SYNTHETIC;

EID: 10744220951     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.00615     Document Type: Review
Times cited : (67)

References (89)
  • 2
    • 0028955675 scopus 로고
    • Host age as a determinant of naturally acquired immunity to Plasmodium falciparum
    • Baird, J. (1995). Host age as a determinant of naturally acquired immunity to Plasmodium falciparum. Parasitol. Today 11, 105-111.
    • (1995) Parasitol. Today , vol.11 , pp. 105-111
    • Baird, J.1
  • 3
    • 0031837486 scopus 로고    scopus 로고
    • Age-dependent characteristics of protection versus susceptibility to Plasmodium falciparum
    • Baird, J. K. (1998). Age-dependent characteristics of protection versus susceptibility to Plasmodium falciparum. Ann. Trop. Med. Parasitol. 92, 367-390.
    • (1998) Ann. Trop. Med. Parasitol. , vol.92 , pp. 367-390
    • Baird, J.K.1
  • 4
    • 0002074761 scopus 로고    scopus 로고
    • Malaria vaccines: Attacking infected erythrocytes
    • ed. S. L Hoffman, Washington, DC: ASM Press
    • Berzins, K. and Perlmann, P. (1996). Malaria vaccines: attacking infected erythrocytes. In Malaria Vaccine Development: A Multi-Immune Response Approach (ed. S. L Hoffman), pp. 105-144. Washington, DC: ASM Press.
    • (1996) Malaria Vaccine Development: A Multi-Immune Response Approach , pp. 105-144
    • Berzins, K.1    Perlmann, P.2
  • 5
    • 0029098383 scopus 로고
    • Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages
    • Bouharoun-Tayoun, H., Oeuvray, C., Lunel, F. and Druilhe, P. (1995). Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages. J. Exp. Med. 182, 409-418.
    • (1995) J. Exp. Med. , vol.182 , pp. 409-418
    • Bouharoun-Tayoun, H.1    Oeuvray, C.2    Lunel, F.3    Druilhe, P.4
  • 6
    • 0034972445 scopus 로고    scopus 로고
    • Ears of the hippopotamus: Manifestations, determinants, and estimates of the malaria burden
    • Breman, J. G. (2001). Ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. Am. J. Trop. Med. Hyg. 64, 1-11.
    • (2001) Am. J. Trop. Med. Hyg. , vol.64 , pp. 1-11
    • Breman, J.G.1
  • 7
    • 0035665932 scopus 로고    scopus 로고
    • FLEXGene repository: From sequenced genomes to gene repositories for high-throughput functional biology and proteomics
    • Brizuela, L., Braun, P. and Labaer, J. (2001). FLEXGene repository: from sequenced genomes to gene repositories for high-throughput functional biology and proteomics. Mol. Biochem. Parasit. 118, 155-165.
    • (2001) Mol. Biochem. Parasit. , vol.118 , pp. 155-165
    • Brizuela, L.1    Braun, P.2    Labaer, J.3
  • 8
    • 0004017976 scopus 로고    scopus 로고
    • Preventing cytoadherence of infected erythrocytes to endothelial cells and noninfected erythrocytes
    • ed. S. L Hoffman, Washington, DC: ASM Press
    • Brown, G. and Rogerson, S. J. (1996). Preventing cytoadherence of infected erythrocytes to endothelial cells and noninfected erythrocytes. In Malaria Vaccine Development: A Multi-Immune Response Approach (ed. S. L Hoffman), pp. 145-166. Washington, DC: ASM Press.
    • (1996) Malaria Vaccine Development: A Multi-Immune Response Approach , pp. 145-166
    • Brown, G.1    Rogerson, S.J.2
  • 11
    • 0015736375 scopus 로고
    • Specificity of protection of man immunized against sporozoite-induced falciparum malaria
    • Clyde, D. F., McCarthy, V. C., Miller, R. M. and Hornick, R. B. (1973), Specificity of protection of man immunized against sporozoite-induced falciparum malaria. Am. J. Med. Sci. 266, 398-401.
    • (1973) Am. J. Med. Sci. , vol.266 , pp. 398-401
    • Clyde, D.F.1    McCarthy, V.C.2    Miller, R.M.3    Hornick, R.B.4
  • 12
    • 0015699215 scopus 로고
    • Immunization of man against sporozoite-induced falciparum malaria
    • Clyde, D. F., Most, H., McCarthy, V. C. and Vanderberg, J. P. (1973). Immunization of man against sporozoite-induced falciparum malaria. Am. J. Med. Sci. 266, 169-177.
    • (1973) Am. J. Med. Sci. , vol.266 , pp. 169-177
    • Clyde, D.F.1    Most, H.2    McCarthy, V.C.3    Vanderberg, J.P.4
  • 13
    • 8144224632 scopus 로고
    • Gamma-globulin and acquired immunity to human malaria
    • Cohen, S., McGregor, I. A. and Carrington, S. (1961). Gamma-globulin and acquired immunity to human malaria. Nature 192, 733-737.
    • (1961) Nature , vol.192 , pp. 733-737
    • Cohen, S.1    McGregor, I.A.2    Carrington, S.3
  • 14
    • 0036047984 scopus 로고    scopus 로고
    • Nonhuman primate models. I. Nonhuman primate host-parasite combinations
    • Collins, W. E. (2002). Nonhuman primate models. I. Nonhuman primate host-parasite combinations. Methods Mol. Med. 72, 77-84.
    • (2002) Methods Mol. Med. , vol.72 , pp. 77-84
    • Collins, W.E.1
  • 15
    • 0032765519 scopus 로고    scopus 로고
    • A retrospective examination of sporozoite- and trophozoite-induced infections with Plasmodium falciparum: Development of parasitologic and clinical immunity during primary infection
    • Collins, W. E. and Jeffery, G. M. (1999a). A retrospective examination of sporozoite-and trophozoite-induced infections with Plasmodium falciparum: development of parasitologic and clinical immunity during primary infection. Am. J. Trop. Med. Hyg. 61, 4-19.
    • (1999) Am. J. Trop. Med. Hyg. , vol.61 , pp. 4-19
    • Collins, W.E.1    Jeffery, G.M.2
  • 16
    • 0032791514 scopus 로고    scopus 로고
    • A retrospective examination of secondary sporozoite- and trophozoite-induced infections with Plasmodium falciparum: Development of parasitologic and clinical immunity following secondary infection
    • Collins, W. E. and Jeffery, G. M. (1999b). A retrospective examination of secondary sporozoite-and trophozoite-induced infections with Plasmodium falciparum: development of parasitologic and clinical immunity following secondary infection. Am. J. Trop. Med. Hyg. 61, 20-35.
    • (1999) Am. J. Trop. Med. Hyg. , vol.61 , pp. 20-35
    • Collins, W.E.1    Jeffery, G.M.2
  • 17
    • 0031009693 scopus 로고    scopus 로고
    • Multi-gene vaccination against malaria: A multi-stage, multi-immune response approach
    • Doolan, D. L. and Hoffman, S. L. (1997). Multi-gene vaccination against malaria: a multi-stage, multi-immune response approach. Parasitol. Today 13, 171-178.
    • (1997) Parasitol. Today , vol.13 , pp. 171-178
    • Doolan, D.L.1    Hoffman, S.L.2
  • 19
    • 0034254649 scopus 로고    scopus 로고
    • The complexity of protective immunity against liver-stage malaria
    • Doolan, D. L. and Hoffman, S. L. (2000). The complexity of protective immunity against liver-stage malaria. J. Immunol. 165, 1453-1462.
    • (2000) J. Immunol. , vol.165 , pp. 1453-1462
    • Doolan, D.L.1    Hoffman, S.L.2
  • 20
    • 0034990655 scopus 로고    scopus 로고
    • DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine Operation
    • Doolan, D. L. and Hoffman, S. L. (2001). DNA-based vaccines against malaria: status and promise of the Multi-Stage Malaria DNA Vaccine Operation. Int. J. Parasitol. 31, 753-762.
    • (2001) Int. J. Parasitol. , vol.31 , pp. 753-762
    • Doolan, D.L.1    Hoffman, S.L.2
  • 25
    • 0035414312 scopus 로고    scopus 로고
    • Variant proteins on the surface of malaria-infected erythrocytes - Developing vaccines
    • Duffy, P. E., Craig, A. G. and Baruch, D. I. (2001). Variant proteins on the surface of malaria-infected erythrocytes - developing vaccines. Trends Parasitol. 17, 354-356.
    • (2001) Trends Parasitol. , vol.17 , pp. 354-356
    • Duffy, P.E.1    Craig, A.G.2    Baruch, D.I.3
  • 26
    • 0242658726 scopus 로고    scopus 로고
    • Prime-boost strategies for malaria vaccine development
    • Dunachie, S. J. and Hill, A. V. S. (2003). Prime-boost strategies for malaria vaccine development. J. Exp. Biol. 206, 3771-3779.
    • (2003) J. Exp. Biol. , vol.206 , pp. 3771-3779
    • Dunachie, S.J.1    Hill, A.V.S.2
  • 30
    • 0033178522 scopus 로고    scopus 로고
    • Immune effector mechanisms in malaria
    • Good, M. F. and Doolan, D. L. (1999). Immune effector mechanisms in malaria. Curr. Opin. Immunol. 11, 412-419.
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 412-419
    • Good, M.F.1    Doolan, D.L.2
  • 31
    • 0033016717 scopus 로고    scopus 로고
    • Correlation between protein and mRNA abundance in yeast
    • Gygi, S. P., Rochon, Y., Franza, B. R. and Aebersold, R. (1999). Correlation between protein and mRNA abundance in yeast. Mol. Cell. Biol. 19, 1720-1730.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1720-1730
    • Gygi, S.P.1    Rochon, Y.2    Franza, B.R.3    Aebersold, R.4
  • 32
    • 0033982165 scopus 로고    scopus 로고
    • Shotgun DNA microarrays and stage-specific gene expression in Plasmodium falciparum malaria
    • Hayward, R. E., Derisi, J. L., Alfadhli, S., Kaslow, D. C., Brown, P. O. and Rathod, P. K. (2000). Shotgun DNA microarrays and stage-specific gene expression in Plasmodium falciparum malaria. Mol. Microbiol. 35, 6-14.
    • (2000) Mol. Microbiol. , vol.35 , pp. 6-14
    • Hayward, R.E.1    Derisi, J.L.2    Alfadhli, S.3    Kaslow, D.C.4    Brown, P.O.5    Rathod, P.K.6
  • 33
    • 0031728356 scopus 로고    scopus 로고
    • From genomics to vaccines: Malaria as a model system
    • Hoffman, S. L., Rogers, W. O., Carucci, D. J. and Venter, J. C. (1998). From genomics to vaccines: malaria as a model system. Nat. Med. 4, 1351-1353.
    • (1998) Nat. Med. , vol.4 , pp. 1351-1353
    • Hoffman, S.L.1    Rogers, W.O.2    Carucci, D.J.3    Venter, J.C.4
  • 35
    • 0037034044 scopus 로고    scopus 로고
    • Plasmodium, human and Anopheles genomics and malaria
    • Hoffman, S. L., Subramanian, G. M., Collins, F. H. and Venter, J. C. (2002b). Plasmodium, human and Anopheles genomics and malaria. Nature 415, 702-709.
    • (2002) Nature , vol.415 , pp. 702-709
    • Hoffman, S.L.1    Subramanian, G.M.2    Collins, F.H.3    Venter, J.C.4
  • 36
    • 0242673680 scopus 로고    scopus 로고
    • Malaria: A complex disease that may require a complex vaccine
    • in press. (ed. M. M. Levine, J. B. Kaper, R. Rappuoli, M. Liu and M. F. Good). New York, NY: Marcel Dekker, Inc.
    • Hoffman, S. L., Doolan, D. L. and Richie, T. L. (in press). Malaria: a complex disease that may require a complex vaccine. In New Generation Vaccines (ed. M. M. Levine, J. B. Kaper, R. Rappuoli, M. Liu and M. F. Good). New York, NY: Marcel Dekker, Inc.
    • New Generation Vaccines
    • Hoffman, S.L.1    Doolan, D.L.2    Richie, T.L.3
  • 37
    • 0002316950 scopus 로고    scopus 로고
    • Preventing merozoite invasion of erythrocytes
    • ed. S. L. Hoffman, Washington, DC: ASM Press
    • Holder, A. A. (1996). Preventing merozoite invasion of erythrocytes. In Malaria Vacćine Development (ed. S. L. Hoffman), pp. 77-104. Washington, DC: ASM Press.
    • (1996) Malaria Vacćine Development , pp. 77-104
    • Holder, A.A.1
  • 39
    • 0013977018 scopus 로고
    • Epidemiological significance of repeated infections with homologous and heterologous strains and species of Plasmodium
    • Jeffery, G. M. (1966). Epidemiological significance of repeated infections with homologous and heterologous strains and species of Plasmodium. Bull. World Health Org. 35, 873-882.
    • (1966) Bull. World Health Org. , vol.35 , pp. 873-882
    • Jeffery, G.M.1
  • 41
    • 0032745349 scopus 로고    scopus 로고
    • Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine
    • Lalvani, A., Moris, P., Voss, G., Pathan, A. A., Kester, K. E., Brookes, R., Lee, E., Koutsoukos, M., Plebanski, M., Delchambre, M. et al., (1999). Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine. J. Infect. Dis. 180, 1656-1664.
    • (1999) J. Infect. Dis. , vol.180 , pp. 1656-1664
    • Lalvani, A.1    Moris, P.2    Voss, G.3    Pathan, A.A.4    Kester, K.E.5    Brookes, R.6    Lee, E.7    Koutsoukos, M.8    Plebanski, M.9    Delchambre, M.10
  • 45
    • 0036479098 scopus 로고    scopus 로고
    • Transcriptionally active polymerase chain reaction (TAP): High throughput gene expression using genome sequence data
    • Liang, X., Teng, A., Braun, D. M., Felgner, J., Wang, Y., Baker, S. I., Chen, S., Zelphati, O. and Feigner, P. L. (2002). Transcriptionally active polymerase chain reaction (TAP): high throughput gene expression using genome sequence data. J. Biol. Chem. 211, 3593-3598.
    • (2002) J. Biol. Chem. , vol.211 , pp. 3593-3598
    • Liang, X.1    Teng, A.2    Braun, D.M.3    Felgner, J.4    Wang, Y.5    Baker, S.I.6    Chen, S.7    Zelphati, O.8    Feigner, P.L.9
  • 46
    • 0242490284 scopus 로고    scopus 로고
    • Progress in the development of recombinant and synthetic blood-stage malaria vaccines
    • Mahanty, S., Saul, A. and Miller, L. H. (2003). Progress in the development of recombinant and synthetic blood-stage malaria vaccines. J. Exp. Biol. 206, 3781-3788.
    • (2003) J. Exp. Biol. , vol.206 , pp. 3781-3788
    • Mahanty, S.1    Saul, A.2    Miller, L.H.3
  • 48
    • 0028922489 scopus 로고
    • Relationships between Plasmodium falciparum transmission by vector populations and the incidence of severe disease at nine sites on the Kenyan coast
    • Mbogo, C. N., Snow, R. W., Khamala, C. P., Kabiru, E. W., Ouma, J. H., Githure, J. I., Marsh, K. and Beier, J. C. (1995). Relationships between Plasmodium falciparum transmission by vector populations and the incidence of severe disease at nine sites on the Kenyan coast. Am. J. Trop. Med. Hyg. 52, 201-206.
    • (1995) Am. J. Trop. Med. Hyg. , vol.52 , pp. 201-206
    • Mbogo, C.N.1    Snow, R.W.2    Khamala, C.P.3    Kabiru, E.W.4    Ouma, J.H.5    Githure, J.I.6    Marsh, K.7    Beier, J.C.8
  • 50
    • 0028135194 scopus 로고
    • Predicting outcome in malaria: Correlation between rate of exposure to infected mosquitoes and level of Plasmodium falciparum parasitemia
    • McElroy, P. D., Beier, J. C., Oster, C. N., Beadle, C., Sherwood, J. A., Oloo, A. J. and Hoffman, S. L. (1994). Predicting outcome in malaria: correlation between rate of exposure to infected mosquitoes and level of Plasmodium falciparum parasitemia. Am. J. Trop. Med. Hyg. 51, 523-532.
    • (1994) Am. J. Trop. Med. Hyg. , vol.51 , pp. 523-532
    • McElroy, P.D.1    Beier, J.C.2    Oster, C.N.3    Beadle, C.4    Sherwood, J.A.5    Oloo, A.J.6    Hoffman, S.L.7
  • 51
    • 0030609547 scopus 로고    scopus 로고
    • Dose- and time-dependent relations between infective Anopheles inoculation and outcomes of Plasmodium falciparum parasitemia among children in western Kenya
    • McElroy, P. D., Beier, J. C., Oster, C. N., Onyango, F. K., Oloo, A. J., Lin, X., Beadle, C. and Hoffman, S. L. (1997). Dose-and time-dependent relations between infective Anopheles inoculation and outcomes of Plasmodium falciparum parasitemia among children in western Kenya. Am. J. Epidemiol. 145, 945-956.
    • (1997) Am. J. Epidemiol. , vol.145 , pp. 945-956
    • McElroy, P.D.1    Beier, J.C.2    Oster, C.N.3    Onyango, F.K.4    Oloo, A.J.5    Lin, X.6    Beadle, C.7    Hoffman, S.L.8
  • 52
    • 0000611648 scopus 로고
    • Treatment of East African P. falciparum malaria with West African human gamma-globulin
    • McGregor, I. A. and Carrington, S. P. (1963). Treatment of East African P. falciparum malaria with West African human gamma-globulin. Trans. R. Soc. Trop. Med. Hyg. 57, 170-175.
    • (1963) Trans. R. Soc. Trop. Med. Hyg. , vol.57 , pp. 170-175
    • McGregor, I.A.1    Carrington, S.P.2
  • 53
    • 0028129356 scopus 로고
    • Malaria pathogenesis
    • Miller, L. H., Good, M. F. and Milon, G. (1994). Malaria pathogenesis. Science 264, 1878-1883.
    • (1994) Science , vol.264 , pp. 1878-1883
    • Miller, L.H.1    Good, M.F.2    Milon, G.3
  • 55
    • 0024312642 scopus 로고
    • Rationale for the development of an engineered sporozoite malaria vaccine
    • Nussenzweig, V. and Nussenzweig, R. S. (1989). Rationale for the development of an engineered sporozoite malaria vaccine. Adv. Immunol. 45, 283-334.
    • (1989) Adv. Immunol. , vol.45 , pp. 283-334
    • Nussenzweig, V.1    Nussenzweig, R.S.2
  • 56
    • 0014202885 scopus 로고
    • Protective immunity produced by the injection of X-irradiated sporozoites of Plasmodium berghei
    • Nussenzweig, R. S., Vanderberg, J., Most, H. and Orton, C. (1967). Protective immunity produced by the injection of X-irradiated sporozoites of Plasmodium berghei. Nature 216, 160-162.
    • (1967) Nature , vol.216 , pp. 160-162
    • Nussenzweig, R.S.1    Vanderberg, J.2    Most, H.3    Orton, C.4
  • 58
    • 0034044126 scopus 로고    scopus 로고
    • The immunology of malaria infection
    • Plebanski, M. and Hill, A. V. (2000). The immunology of malaria infection. Curr. Opin. Immunol. 12, 437-441.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 437-441
    • Plebanski, M.1    Hill, A.V.2
  • 60
    • 0036047608 scopus 로고    scopus 로고
    • Mouse models for preerythrocytic-stage malaria
    • Renia, L., Belnoue, E. and Landau, I. (2002). Mouse models for preerythrocytic-stage malaria. Methods Mol. Med 72, 41-55.
    • (2002) Methods Mol. Med , vol.72 , pp. 41-55
    • Renia, L.1    Belnoue, E.2    Landau, I.3
  • 61
    • 0037033980 scopus 로고    scopus 로고
    • Progress and challenges for malaria vaccines
    • Richie, T. L. and Saul, A. (2002). Progress and challenges for malaria vaccines. Nature 415, 694-701.
    • (2002) Nature , vol.415 , pp. 694-701
    • Richie, T.L.1    Saul, A.2
  • 62
    • 0034860454 scopus 로고    scopus 로고
    • Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques
    • Rogers, W. O., Baird, J. K., Kumar, A., Tine, J. A., Weiss, W., Aguiar, J. C., Gowda, K., Gwadz, R., Kumar, S., Gold, M. et al. (2001). Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques. Infect. Immun. 69, 5565-5572.
    • (2001) Infect. Immun. , vol.69 , pp. 5565-5572
    • Rogers, W.O.1    Baird, J.K.2    Kumar, A.3    Tine, J.A.4    Weiss, W.5    Aguiar, J.C.6    Gowda, K.7    Gwadz, R.8    Kumar, S.9    Gold, M.10
  • 64
    • 0036157820 scopus 로고    scopus 로고
    • Laser capture microdissection and molecular analysis of Plasmodium yoelii liver-stage parasites
    • Sacci, J. B., Jr, Aguiar, J. C., Lau, A. O. and Hoffman, S. L. (2002). Laser capture microdissection and molecular analysis of Plasmodium yoelii liver-stage parasites. Mol. Biochem. Parasitol. 119, 285-289.
    • (2002) Mol. Biochem. Parasitol. , vol.119 , pp. 285-289
    • Sacci J.B., Jr.1    Aguiar, J.C.2    Lau, A.O.3    Hoffman, S.L.4
  • 67
    • 0037102205 scopus 로고    scopus 로고
    • Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria
    • Schofield, L., Hewitt, M. C., Evans, K., Siomos, M. A. and Seeberger, P. H. (2002). Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature 418, 785-789.
    • (2002) Nature , vol.418 , pp. 785-789
    • Schofield, L.1    Hewitt, M.C.2    Evans, K.3    Siomos, M.A.4    Seeberger, P.H.5
  • 68
    • 0028077102 scopus 로고
    • Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein
    • Sedegah, M., Hedstrom, R. C., Hobart, P. and Hoffman, S. L. (1994). Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein. Proc. Natl. Acad. Sci. USA 91, 9866-9870.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9866-9870
    • Sedegah, M.1    Hedstrom, R.C.2    Hobart, P.3    Hoffman, S.L.4
  • 71
    • 0032146234 scopus 로고    scopus 로고
    • HLA supertypes and supermotifs: A functional perspective on HLA polymorphism
    • Sette, A. and Sidney, J. (1998). HLA supertypes and supermotifs: a functional perspective on HLA polymorphism. Curr. Opin. Immunol. 10, 478-482.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 478-482
    • Sette, A.1    Sidney, J.2
  • 72
    • 0033388724 scopus 로고    scopus 로고
    • Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism
    • Sette, A. and Sidney, J. (1999). Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism. Immunogenetics 50, 201-212.
    • (1999) Immunogenetics , vol.50 , pp. 201-212
    • Sette, A.1    Sidney, J.2
  • 73
    • 0035697665 scopus 로고    scopus 로고
    • The development of multi-epitope vaccines: Epitope identification, vaccine design and clinical evaluation
    • Sette, A., Livingston, B., McKinney, D., Appella, E., Fikes, J., Sidney, J., Newman, M. and Chesnut, R. (2001). The development of multi-epitope vaccines: epitope identification, vaccine design and clinical evaluation. Biologicals 29, 271-276.
    • (2001) Biologicals , vol.29 , pp. 271-276
    • Sette, A.1    Livingston, B.2    McKinney, D.3    Appella, E.4    Fikes, J.5    Sidney, J.6    Newman, M.7    Chesnut, R.8
  • 77
    • 0031912586 scopus 로고    scopus 로고
    • Risk of severe malaria among African infants: Direct evidence of clinical protection during early infancy
    • Snow, R. W., Nahlen, B., Palmer, A., Donnelly, C. A., Gupta, S. and Marsh, K. (1998). Risk of severe malaria among African infants: direct evidence of clinical protection during early infancy. J. Infect. Dis. 177, 819-822.
    • (1998) J. Infect. Dis. , vol.177 , pp. 819-822
    • Snow, R.W.1    Nahlen, B.2    Palmer, A.3    Donnelly, C.A.4    Gupta, S.5    Marsh, K.6
  • 79
    • 0032894502 scopus 로고    scopus 로고
    • Linear expression elements: A rapid, in vivo, method to screen for gene functions
    • Sykes, K. F. and Johnston, S. A. (1999). Linear expression elements: a rapid, in vivo, method to screen for gene functions. Nat. Biotech. 17, 355-359.
    • (1999) Nat. Biotech. , vol.17 , pp. 355-359
    • Sykes, K.F.1    Johnston, S.A.2
  • 80
    • 0035662341 scopus 로고    scopus 로고
    • Comparative genomics in Plasmodium: A tool for the identification of genes and functional analysis
    • Thompson, J., Janse, C. J. and Waters, A. P. (2001). Comparative genomics in Plasmodium: a tool for the identification of genes and functional analysis. Mol. Biochem. Parasitol. 118, 147-154.
    • (2001) Mol. Biochem. Parasitol. , vol.118 , pp. 147-154
    • Thompson, J.1    Janse, C.J.2    Waters, A.P.3
  • 82
    • 0033981458 scopus 로고    scopus 로고
    • Apparent tolerance of Plasmodium falciparum in infants in a highly endemic area
    • Vounatsou, P., Smith, T., Kitua, A. Y., Alonso, P. L. and Tanner, M. (2000). Apparent tolerance of Plasmodium falciparum in infants in a highly endemic area. Parasitology 120, 1-9.
    • (2000) Parasitology , vol.120 , pp. 1-9
    • Vounatsou, P.1    Smith, T.2    Kitua, A.Y.3    Alonso, P.L.4    Tanner, M.5
  • 83
    • 0036535357 scopus 로고    scopus 로고
    • Analysis of quantitative proteomic data generated via multidimensional protein identification technology
    • Washburn, M. P., Ulaszek, R., Deciu, C., Schieltz, D. M. and Yates, J. R., III (2002). Analysis of quantitative proteomic data generated via multidimensional protein identification technology. Anal. Chem. 74, 1650-1657.
    • (2002) Anal. Chem. , vol.74 , pp. 1650-1657
    • Washburn, M.P.1    Ulaszek, R.2    Deciu, C.3    Schieltz, D.M.4    Yates J.R. III5
  • 84
    • 0037192111 scopus 로고    scopus 로고
    • Orthology between the genomes of Plasmodium falciparum and rodent malaria parasites: Possible practical applications
    • Waters, A. P. (2002). Orthology between the genomes of Plasmodium falciparum and rodent malaria parasites: possible practical applications. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 357, 55-63.
    • (2002) Philos. Trans. R. Soc. Lond. B. Biol. Sci. , vol.357 , pp. 55-63
    • Waters, A.P.1
  • 85
    • 0038691942 scopus 로고    scopus 로고
    • Characterisation of the merozoite surface protein-2 promoter using stable and transient transfection in Plasmodium falciparum
    • Wickham, M. E., Thompson, J. K. and Cowman, A. F. (2003). Characterisation of the merozoite surface protein-2 promoter using stable and transient transfection in Plasmodium falciparum. Mol. Biochem. Parasitol. 129, 147-156.
    • (2003) Mol. Biochem. Parasitol. , vol.129 , pp. 147-156
    • Wickham, M.E.1    Thompson, J.K.2    Cowman, A.F.3
  • 86
    • 0037015613 scopus 로고    scopus 로고
    • Biological revelations
    • Wirth, D. F. (2002). Biological revelations. Nature 419, 495-496.
    • (2002) Nature , vol.419 , pp. 495-496
    • Wirth, D.F.1
  • 87
    • 0035662344 scopus 로고    scopus 로고
    • Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy
    • Witney, A. A., Doolan, D. L., Anthony, R. M., Weiss, W. R., Hoffman, S. L. and Carucci, D. J. (2001). Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy. Mol. Biochem. Parasitol. 118, 233-245.
    • (2001) Mol. Biochem. Parasitol. , vol.118 , pp. 233-245
    • Witney, A.A.1    Doolan, D.L.2    Anthony, R.M.3    Weiss, W.R.4    Hoffman, S.L.5    Carucci, D.J.6
  • 88
    • 39049116299 scopus 로고    scopus 로고
    • World Health Organization (2002). WHO Report, http://www.who.int/ infections-disease-report/2002/index. html.
    • (2002) WHO Report


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