-
1
-
-
0346557249
-
Gefitinib (ZD1839) as first line, compassionate use therapy in patients (pts) with advanced non-small-cell lung cancer (NSCLC)
-
Argiris A, Mittal N, Masters G (2003) Gefitinib (ZD1839) as first line, compassionate use therapy in patients (pts) with advanced non-small-cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 22: A2729
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Argiris, A.1
Mittal, N.2
Masters, G.3
-
2
-
-
0033646738
-
Hemopoietic reserve in the older cancer patient: Clinical and economic considerations
-
Balducci L, Hardy CL, Lyman GH (2000) Hemopoietic reserve in the older cancer patient: clinical and economic considerations. Cancer Control 7: 539-547
-
(2000)
Cancer Control
, vol.7
, pp. 539-547
-
-
Balducci, L.1
Hardy, C.L.2
Lyman, G.H.3
-
3
-
-
0842284637
-
-
Common toxicity criteria: National Institute of Health, Cancer Therapy Evaluation Program, Division of Cancer Treatment (1993). Bethesda
-
Common toxicity criteria: National Institute of Health, Cancer Therapy Evaluation Program, Division of Cancer Treatment (1993). Bethesda
-
-
-
-
4
-
-
2442579924
-
Gefitinib in elderly patients with non-small cell lung cancer (NSCLC)
-
Copin M, Kommareddy A, Behnken D, McLeod H, Trinkaus K, Ali A, Read W, Govindan R (2003) Gefitinib in elderly patients with non-small cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 22: A3048
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Copin, M.1
Kommareddy, A.2
Behnken, D.3
McLeod, H.4
Trinkaus, K.5
Ali, A.6
Read, W.7
Govindan, R.8
-
5
-
-
0034095853
-
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens
-
The TAX 320 Non-Small Cell Lung Cancer Study Group.
-
Fossella FV, DeVore R, Kerr RN, Crawford J, Natale RR, Dunphy F, Kalman L, Miller V, Lee JS, Moore M, Gandara D, Karp D, Vokes E, Kris M, Kim Y, Gamza F, Hammershaimb L (2000) Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group. J Clin Oncol 18: 2354-2362
-
(2000)
J Clin Oncol
, vol.18
, pp. 2354-2362
-
-
Fossella, F.V.1
DeVore, R.2
Kerr, R.N.3
Crawford, J.4
Natale, R.R.5
Dunphy, F.6
Kalman, L.7
Miller, V.8
Lee, J.S.9
Moore, M.10
Gandara, D.11
Karp, D.12
Vokes, E.13
Kris, M.14
Kim, Y.15
Gamza, F.16
Hammershaimb, L.17
-
6
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer
-
Fukuoka M, Yano S, Giaccone G, Tamura T, Nakagawa K, Douillard JY, Nishiwaki Y, Vansteenkiste J, Kudoh S, Rischin D, Eek R, Horai T, Noda K, Takata I, Smit E, Averbuch S, Macleod A, Feyereislova A, Dong RP, Baselga J (2003) Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J Clin Oncol 21: 2237-2246
-
(2003)
J Clin Oncol
, vol.21
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
Tamura, T.4
Nakagawa, K.5
Douillard, J.Y.6
Nishiwaki, Y.7
Vansteenkiste, J.8
Kudoh, S.9
Rischin, D.10
Eek, R.11
Horai, T.12
Noda, K.13
Takata, I.14
Smit, E.15
Averbuch, S.16
Macleod, A.17
Feyereislova, A.18
Dong, R.P.19
Baselga, J.20
more..
-
7
-
-
50549174560
-
The determination of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent
-
Gehan EA (1961) The determination of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent. J Chronic Dis 13: 346-353
-
(1961)
J Chronic Dis
, vol.13
, pp. 346-353
-
-
Gehan, E.A.1
-
9
-
-
0037420202
-
Chemotherapy for elderly patients with advanced non-small-cell lung cancer: The Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial
-
Gridelli C, Perrone F, Gallo C, Cigolari S, Rossi A, Piantedosi F, Barbera S, Ferrau F, Piazza E, Rosetti F, Clerici M, Bertetto O, Robbiati SF, Frontini L, Sacco C, Castiglione F, Favaretto A, Novello S, Migliorino MR, Gasparini G, Galetta D, Iaffaioli RV, Gebbia V (2003) Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial. J Natl Cancer Inst 95: 362-372
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 362-372
-
-
Gridelli, C.1
Perrone, F.2
Gallo, C.3
Cigolari, S.4
Rossi, A.5
Piantedosi, F.6
Barbera, S.7
Ferrau, F.8
Piazza, E.9
Rosetti, F.10
Clerici, M.11
Bertetto, O.12
Robbiati, S.F.13
Frontini, L.14
Sacco, C.15
Castiglione, F.16
Favaretto, A.17
Novello, S.18
Migliorino, M.R.19
Gasparini, G.20
Galetta, D.21
Iaffaioli, R.V.22
Gebbia, V.23
more..
-
10
-
-
0042676766
-
A phase III study of pemetrexed versus docetaxel in patients with recurrent non-small cell lung cancer (NSCLC) who were previously treated with chemotherapy
-
Hanna NH, Shepherd FA, Rosell R, Pereira JR, De Marinis F, Fossella F, Kayitalire L, Paul S, Einhorn LH, Bunn PA (2003) A phase III study of pemetrexed versus docetaxel in patients with recurrent non-small cell lung cancer (NSCLC) who were previously treated with chemotherapy. Proc Am Soc Clin Oncol 22: A2503
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Hanna, N.H.1
Shepherd, F.A.2
Rosell, R.3
Pereira, J.R.4
De Marinis, F.5
Fossella, F.6
Kayitalire, L.7
Paul, S.8
Einhorn, L.H.9
Bunn, P.A.10
-
11
-
-
0033392005
-
Epidermal growth factor receptor inhibition in cancer therapy: Biology, rationale and preliminary clinical results
-
Huang SM, Harari PM (1999) Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results. Invest New Drugs 17: 259-269
-
(1999)
Invest New Drugs
, vol.17
, pp. 259-269
-
-
Huang, S.M.1
Harari, P.M.2
-
12
-
-
0033619959
-
Underrepresentation of patients 65 years of age or older in cancer-treatment trials
-
Hutchins LF, Unger JM, Crowley JJ, Coltman Jr CA, Albain KS (1999) Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N Engl J Med 341: 2061-2067
-
(1999)
N Engl J Med
, vol.341
, pp. 2061-2067
-
-
Hutchins, L.F.1
Unger, J.M.2
Crowley, J.J.3
Coltman Jr., C.A.4
Albain, K.S.5
-
13
-
-
0037431759
-
Severe acute interstitial pneumonia and gefitinib
-
Inoue A, Saijo Y, Maemondo M, Gomi K, Tokue Y, Kimura Y, Ebina M, Kikuchi T, Moriya T, Nukiwa T (2003) Severe acute interstitial pneumonia and gefitinib. Lancet 361: 137-139
-
(2003)
Lancet
, vol.361
, pp. 137-139
-
-
Inoue, A.1
Saijo, Y.2
Maemondo, M.3
Gomi, K.4
Tokue, Y.5
Kimura, Y.6
Ebina, M.7
Kikuchi, T.8
Moriya, T.9
Nukiwa, T.10
-
14
-
-
0013113593
-
ZD1839 ('Iressa') shows antitumor activity in patients with recurrent non-small cell lung cancer treated on a compassionate use protocol
-
Janne PA, Ostler PA, Lucca J, Fidias P, Skarin AT, Lynch TJ, Johnson BE, Farber D (2002) ZD1839 ('Iressa') shows antitumor activity in patients with recurrent non-small cell lung cancer treated on a compassionate use protocol. Proc Am Soc Clin Oncol 21: A1274
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Janne, P.A.1
Ostler, P.A.2
Lucca, J.3
Fidias, P.4
Skarin, A.T.5
Lynch, T.J.6
Johnson, B.E.7
Farber, D.8
-
15
-
-
0842327858
-
Gefitinib as a first line therapy for patients with advanced non small cell lung cancer (NSCLC)
-
Kommareddy A, Coplin M, Behnken D, Romvari E, Trinkaus K, Read W, Govindan RT (2003) Gefitinib as a first line therapy for patients with advanced non small cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 22: A2834
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Kommareddy, A.1
Coplin, M.2
Behnken, D.3
Romvari, E.4
Trinkaus, K.5
Read, W.6
Govindan, R.T.7
-
16
-
-
0001174063
-
Objective regression in non-small cell lung cancer patients treated in phase I trials of oral ZD 1839 (Iressa), a selective tyrosine kinase inhibitor that blocks the epidermal growth factor receptor (EGFR)
-
abstract 233
-
Kris MG, Herbst R, Rischin D, LoRusso P, Baselga J, Hammond L, Feyereislova A, Ochs J, Averbuch S (2000) Objective regression in non-small cell lung cancer patients treated in phase I trials of oral ZD 1839 (Iressa), a selective tyrosine kinase inhibitor that blocks the epidermal growth factor receptor (EGFR). Lung Cancer 29(Suppl 1): 72 (abstract 233)
-
(2000)
Lung Cancer
, vol.29
, Issue.1 SUPPL.
, pp. 72
-
-
Kris, M.G.1
Herbst, R.2
Rischin, D.3
Lorusso, P.4
Baselga, J.5
Hammond, L.6
Feyereislova, A.7
Ochs, J.8
Averbuch, S.9
-
17
-
-
0001303063
-
A phase II trial of ZD 1839 (Iressa) in advanced non-small cell lung cancer (NSCLC) patients who had failed platinum- And docetaxel-based regimens (IDEAL 2)
-
Kris MG, Natale RB, Herbst RS, Lynch Jr TJ, Prager D, Belani CP, Schiller JH, Kelly K, Spiridonidis C, Albani KS, Brahmer JR, Sandier A, Crawford J, Lutzker SG, Lilenbaum R, Helms L, Wolf M, Averbuch S, Ochs J, Kay A (2002) A phase II trial of ZD 1839 (Iressa) in advanced non-small cell lung cancer (NSCLC) patients who had failed platinum-and docetaxel-based regimens (IDEAL 2). Proc Am Soc Clin Oncol 21: 292a
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
Lynch Jr., T.J.4
Prager, D.5
Belani, C.P.6
Schiller, J.H.7
Kelly, K.8
Spiridonidis, C.9
Albani, K.S.10
Brahmer, J.R.11
Sandier, A.12
Crawford, J.13
Lutzker, S.G.14
Lilenbaum, R.15
Helms, L.16
Wolf, M.17
Averbuch, S.18
Ochs, J.19
Kay, A.20
more..
-
18
-
-
0037028750
-
Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer, implications of Eastern Cooperative Oncology Group 5592, a randomized trial
-
Langer CJ, Manola J, Bernardo P, Kugler JW, Bonomi P, Cella D, Johnson DH (2002) Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer, implications of Eastern Cooperative Oncology Group 5592, a randomized trial. J Natl Cancer Inst 94: 173-181
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 173-181
-
-
Langer, C.J.1
Manola, J.2
Bernardo, P.3
Kugler, J.W.4
Bonomi, P.5
Cella, D.6
Johnson, D.H.7
-
19
-
-
0038021580
-
V ZD1839, a novel, oral epidermal growth factor receptor-tyrosine kinase inhibitor, as salvage treatment in patients with advanced non-small cell lung cancer. Experience from a single center participating in a compassionate use program
-
Pallis AG, Mavroudis D, Androulakis N, Souglakos J, Kouroussis C, Bozionelou V, Vlachonikolis IG, Georgoulias V (2003) V ZD1839, a novel, oral epidermal growth factor receptor-tyrosine kinase inhibitor, as salvage treatment in patients with advanced non-small cell lung cancer. Experience from a single center participating in a compassionate use program. Lung Cancer 40: 301-307
-
(2003)
Lung Cancer
, vol.40
, pp. 301-307
-
-
Pallis, A.G.1
Mavroudis, D.2
Androulakis, N.3
Souglakos, J.4
Kouroussis, C.5
Bozionelou, V.6
Vlachonikolis, I.G.7
Georgoulias, V.8
-
20
-
-
0003243810
-
ZD1839 ('Iressa') as a single agent for the treatment of metastatic non-small-cell lung cancer (NSCLC)
-
Ruckdeschel JC, Simon G, Antonia S, Haura E, Williams C, Wagner H, Lima CR, Ettienne K, Vaughn J, Bepler G, Lee Moffitt H (2002) ZD1839 ('Iressa') as a single agent for the treatment of metastatic non-small-cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 21: A1269
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Ruckdeschel, J.C.1
Simon, G.2
Antonia, S.3
Haura, E.4
Williams, C.5
Wagner, H.6
Lima, C.R.7
Ettienne, K.8
Vaughn, J.9
Bepler, G.10
Lee Moffitt, H.11
-
21
-
-
0027159063
-
Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
-
Rusch V, Baselga J, Cordon-Cardo C, Orazem J, Zaman M, Hoda S, McIntosh J, Kurie J, Dmitrovsky E (1993) Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 53: 2379-2385
-
(1993)
Cancer Res
, vol.53
, pp. 2379-2385
-
-
Rusch, V.1
Baselga, J.2
Cordon-Cardo, C.3
Orazem, J.4
Zaman, M.5
Hoda, S.6
McIntosh, J.7
Kurie, J.8
Dmitrovsky, E.9
-
22
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon DS, Brandt R, Ciardiello F, Normanno N (1995) Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19: 183-232
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
23
-
-
0034069620
-
Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy
-
Shepherd FA, Dancey J, Ramlau R, Mattson K, Gralla R, O'Rourke M, Levitan N, Gressot L, Vincent M, Burkes R, Coughlin S, Kim Y, Berille J (2000) Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy. J Clin Oncol 18: 2095-2103
-
(2000)
J Clin Oncol
, vol.18
, pp. 2095-2103
-
-
Shepherd, F.A.1
Dancey, J.2
Ramlau, R.3
Mattson, K.4
Gralla, R.5
O'Rourke, M.6
Levitan, N.7
Gressot, L.8
Vincent, M.9
Burkes, R.10
Coughlin, S.11
Kim, Y.12
Berille, J.13
-
24
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors
-
Therasse P (2000) New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 92: 205-216
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 205-216
-
-
Therasse, P.1
|