The discovery of biaryl acids and amides exhibiting antibacterial activity against Gram-positive bacteria

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 6, 2004, Pages 1423-1426

  Look, Gary C ^a   Vacin, Charles ^b   Dias, Tracy M ^c   Ho, Sun ^d   Tran, Thuy H ^f   Lee, Laurance L ^f   Wiesner, Cedric ^d   Fang, Flora ^d   Marra, Andrea ^e   Westmacott, Don ^d   Hromockyj, Alexander E ^e   Murphy, Martin M ^f   Schullek, John R ^f  

^a RIGEL PHARMACEUTICALS INC   (United States)

^b Cytokinetics Inc   (United States)

^c XenoPort Inc   (United States)

^d PROTEIN DESIGN LABS INC   (United States)

^e PFIZER INC   (United States)

^f Box 558   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID; AMIDE; AMINO ACID; ANTIINFECTIVE AGENT; PDL 115228; PDL 117199; PDL 117219; PDL 117227; PDL 117230; PDL 117279; PDL 141020; PDL 141021; PDL 141024; PDL 141030; PDL 141032; PDL 141052; PDL 141053; PDL 141056; PDL 141613; PDL 141615;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; GRAM POSITIVE BACTERIUM; LIBRARY; NONHUMAN; SOLID; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMIDES; AMINO ACIDS; ANTI-BACTERIAL AGENTS; ESCHERICHIA COLI; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; STAPHYLOCOCCUS AUREUS;

POSIBACTERIA;

EID: 10744220440     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.01.026     Document Type: Article

References (17)

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15. 1H NMR data.
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