Use of DNA for detection and isolation of potential anticancer agents from plants

Pharmacia

Volumn 47, Issue 1-2, 2000, Pages 10-16

  Ionkova, I ^a   Alfermann, A W ^b  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Anticarcinogenic agents; Biological assay; DNA; Plant extracts therapeutic use; Plants, medicinal therapeutic use; Saponins

Indexed keywords

EID: 10644275402     PISSN: 04280296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Bader, G. et al. - Cytotoxicity of triterpenoid saponins, part I: Activities ageinst tumor cells in vitro and hemolytycal inddex. Pharmazie, 51, 1996, No 6, 414.
2. Budzikiewich, H., P. Kormali et I. lonkova. The stereochemistry of Astragalus sapogenines (a new saapogenine from Astragalus aitosensis Ivan). - In: Essays on Science, Ed. H. Said, Karachi, 1992, 75.
3. Gunatilaka L., D. Kingston et R. Johnson. Bioactive ergost-5ene-3,7,-diol derivatives from Pseudobersama mossambicensis. Pure § Appl. Chem., 66, 1994, Nos 10/11: 2219.
4. Gupta, M. et al. Screening of Panamanian plants for brine shrimp toxicity, grown gall tumor inhibitor, cytotoxicity and DNA interaction. - Int. J. Pharmacognosy, 34, 1996, No 1, 19.
5. Ionkova, I. In vitro cultures and formation of secondary metabolites in Astragalus. - In: Biotechnology in Agryculture and Forestry, Medicinal and Aromatic plants, VIII. Ed. Y. P. S. Bajaj, Berlin, Springer Verlag, 1996.
6. Ledniger, D. et K. M. Snader. - In: Economic and medicinal plant research. Eds. H.Wagner and N. Farnswort, 1995, 1-20.
7. Mar, W. et al. Biological Activity of Novel Macrocyclic Alkaloids from Albizia amara detected on the basis of interaction with DNA. - J. Nat. Prod., 54, 1991, 1531.
8. Nikilov, S. et al. Soyasapogenol B from Astragalus augustifolius Lam. - Comp. Rend. Acad. Bul. Sci., 38, 1985, No 7, 875.
9. Pezzutop J. et al. DNA as an affinity probe useful in the detection and isolation of natural products. - J. Nat. Prod., 54, 1991, 1522.