Cytotoxic and genotoxic effect of the [ 166Dy]Dy/ 166Ho-EDTMP in vivo generator system in mice

Nuclear Medicine and Biology

Volumn 31, Issue 8, 2004, Pages 1079-1085

  Pedraza López, Martha ^a   Ferro Flores, Guillermina ^b   Arteaga De Murphy, Consuelo ^a   Morales Ramírez, Pedro ^b   Piedras Ross, Josefa ^a   Murphy Stack, Eduardo ^c   Hernández Oviedo, Omar ^d  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^b INSTITUTO NACIONAL DE INVESTIGACIONES NUCLEARES   (Mexico)

^c Hospital Santelena   (Mexico)

^d INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

166Dy Dy 166Ho EDTMP; Bone marrow ablation; Cytotoxicity; Dysprosium 166; Genotoxicity targeted radiotherapy; Holmium 166; In vivo generator

Indexed keywords

BUFFER; DYSPROSIUM; ETHYLENEDIAMINETETRAMETHYLENEPHOSPHONATE HOLMIUM HO 166; HOLMIUM; PHOSPHATE; PHOSPHONIC ACID DERIVATIVE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BONE MARROW; BONE MARROW SUPPRESSION; CALCULATION; CONTROLLED STUDY; CYTOTOXICITY; DOSIMETRY; DRUG EFFECT; FEMUR; FLOW CYTOMETRY; GENOTOXICITY; HISTOPATHOLOGY; MALE; MONTE CARLO METHOD; MOUSE; NONHUMAN; RADIOCHEMISTRY; THIN LAYER CHROMATOGRAPHY;

ANIMALS; BONE MARROW; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, RADIATION; HALF-LIFE; MICE; MUTAGENICITY TESTS; ORGAN SPECIFICITY; ORGANOMETALLIC COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; RADIOMETRY; RADIOPHARMACEUTICALS; RADIOTHERAPY; RADIOTHERAPY DOSAGE; RETICULOCYTES;

EID: 10644271871     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2004.08.010     Document Type: Article

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