Leaky β-oxidation of a trans-fatty acid: Incomplete β-oxidation of elaidic acid is due to the accumulation of 5-trans-tetradecenoyl-CoA and its hydrolysis and conversion to 5-trans-tetradecenoylcarnitine in the matrix of rat mitochondria

Journal of Biological Chemistry

Volumn 279, Issue 50, 2004, Pages 52160-52167

  Yu, Wenfeng ^a   Liang, Xiquan ^a   Ensenauer, Regina E ^b   Vockley, Jerry ^b   Sweetman, Lawrence ^c   Schulz, Horst ^a,d  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b MAYO CLINIC   (United States)

^c BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^d CITY COLLEGE OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL ORGANS; COENZYMES; GAS CHROMATOGRAPHY; HYDROLYSIS; ISOMERS; MASS SPECTROMETRY; METABOLITES; OLEIC ACID; OXIDATION; STEARIC ACID;

ELAIDIC ACID; MITOCHONDRIA; MITOCHONDRIAL MATRIX; TETRADECENOIC ACID;

FATTY ACIDS;

ACYL COENZYME A; CARNITINE DERIVATIVE; ELAIDIC ACID; ELAIDOYL COENZYME A; LONG CHAIN FATTY ACID; MYRISTOYL COENZYME A; OLEIC ACID; OLEOYL COENZYME A; STEARIC ACID; STEAROYL COENZYME A; TETRADECENOIC ACID; TETRADECENOYL COENZYME A; TETRADECENOYLCARNITINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHEMICAL BOND; CIS TRANS ISOMERISM; CONTROLLED STUDY; DEHYDROGENATION; ENZYME DEGRADATION; ENZYME SUBSTRATE; FATTY ACID ANALYSIS; FATTY ACID OXIDATION; GAS CHROMATOGRAPHY; HEART MITOCHONDRION; HYDROLYSIS; LIVER MITOCHONDRION; MALE; MASS SPECTROMETRY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; FATTY ACIDS, UNSATURATED; HYDROLYSIS; KINETICS; MALE; MITOCHONDRIA, LIVER; OLEIC ACID; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM;

ANIMALIA;

EID: 10644262045     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409640200     Document Type: Article

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