The short-term effect of nifedipine tocolysis on placental, fetal cerebral and atrioventricular Doppler waveforms

Ultrasound in Obstetrics and Gynecology

Volumn 24, Issue 7, 2004, Pages 761-765

  Guclu, S ^a   Saygili, U ^a   Dogan, E ^a   Demir, N ^a   Baschat, A A ^b  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

Atrioventricular valves; Doppler; Middle cerebral artery; Nifedipine; Tocolysis; Umbilical artery; Uterine artery

Indexed keywords

NIFEDIPINE; UTERUS SPASMOLYTIC AGENT;

ADULT; ARTICLE; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; BRAIN CIRCULATION; BRAIN VASCULAR RESISTANCE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOPPLER FLOWMETRY; DRUG CHOICE; DRUG EFFECT; DRUG TOLERABILITY; EVALUATION; FEMALE; FETUS; FETUS CIRCULATION; FETUS HEART RATE; HEART ATRIOVENTRICULAR VALVE; HEART FUNCTION; HEART OUTPUT; HEART RATE; HUMAN; MEASUREMENT; MIDDLE CEREBRAL ARTERY; PARAMETER; PLACENTA CIRCULATION; PREMATURE LABOR; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; TOCOLYSIS; UMBILICAL ARTERY; UTERINE ARTERY; WAVEFORM; WILCOXON SIGNED RANKS TEST;

ADULT; CEREBRAL ARTERIES; ECHOCARDIOGRAPHY, DOPPLER; FEMALE; HUMANS; NIFEDIPINE; OBSTETRIC LABOR, PREMATURE; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, THIRD; REGIONAL BLOOD FLOW; STATISTICS, NONPARAMETRIC; TOCOLYTIC AGENTS; ULTRASONOGRAPHY, DOPPLER; ULTRASONOGRAPHY, PRENATAL; UMBILICAL ARTERIES;

EID: 10644255643     PISSN: 09607692     EISSN: None     Source Type: Journal    
DOI: 10.1002/uog.1770     Document Type: Article

References (22)

1. King JF, Flenady VJ, Papatsonis DN, Dekker GA, Carbonne B. Calcium channel blockers for inhibiting preterm labour. The Cochrane Library, Issue 1, 2003; http://www.update-software.com [Accessed 11 July 2003].
2. Papatsonis DN, Kok JH, van Geijn HP, Bleker OP, Ader HJ, Dekker GA. Neonatal effects of nifedipine and ritodrine for preterm labor. Obstet Gynecol 2000; 95: 477-481.
3. Magee LA, Schick B, Donnenfeld AE, Sage SR, Conover B, Cook L, McElhatton PR, Schmidt MA, Koren G. The safety of calcium channel blockers in human pregnancy: a prospective, multicenter cohort study. Am J Obstet Gynecol 1996; 174: 823-828.
4. Harake B, Gilbert RD, Ashwal S, Power GG. Nifedipine: effects on fetal and maternal hemodynamics in pregnant sheep. Am J Obstet Gynecol 1987; 157: 1003-1008.
5. Ducsay CA, Thompson JS, Wu AT, Novy M. Effects of calcium entry blocker (nicardipine) tocolysis in rhesus macaques: fetal plasma concentrations and cardiorespiratory changes. Am J Obstet Gynecol 1987; 157: 1482-1486.
6. Ulmsten U. Treatment of normotensive and hypertensive patients with preterm labor using oral nifedipine, a calcium antagonist. Arch Gynecol 1984; 236: 69-72.
7. Kupferminc M, Lessing JB, Yaron Y, Peyser MR. Nifedipine versus ritodrine for suppression of preterm labour. Br J Obstet Gynaecol 1993; 100: 1090-1094.
8. Monga M, Creasy RK. Pharmacologic management of preterm labor. Semin Perinatol 1995; 19: 84-96.
9. Wladimiroff JW, Tonge HM, Stewart PA. Doppler ultrasound assessment of cerebral blood flow in the human fetus. Br J Obstet Gynaecol 1986; 93: 471-475.
10. Gramellini D, Folli MC, Raboni S, Vadora E, Merialdi A. Cerebral-umbilical Doppler ratio as a predictor of adverse perinatal outcome. Obstet Gynecol 1992; 79: 416-420.
11. Braunwald E. Mechanisms of action of calcium-channel-blocking agents. N Engl J Med 1982; 307: 1618-1627.
12. Thompson RS, Trudinger BJ, Cook CM. A comparison of Doppler ultrasound waveform indices in the umbilical artery-II. Indices derived from the maximum velocity waveform. Ultrasound Med Biol 1986; 12: 835-844.
13. Sharif DS, Huhta JC, Moise KJ Jr, Morrow RW, Yoon GY. Changes in fetal hemodynamics with terbutaline treatment and premature labor. J Clin Ultrasound 1990; 18: 85-89.
14. Rizzo G, Arduini D, Romanini C. Doppler echocardiographic assessment of fetal cardiac function. Ultrasound Obstet Gynecol 1992; 2: 434-445.
15. Glock JL, Morales WJ. Efficacy and safety of nifedipine versus magnesium sulfate in the management of preterm labor: a randomized study. Am J Obstet Gynecol 1993; 169: 960-964.
16. Csapo AI. Deactivation of the uterus during normal and premature labor at the calcium anatagonist nicardipine. Am J Obstet Gynecol 1982; 142: 483-491.
17. Golichowsky AM. Tocolytic and hemodynamic effects of nifedipine in the ewe. Am J Obstet Gynecol 1985; 151: 1134-1140.
18. Pirhonen JP, Erkkola RU, Ekblad UU, Nyman L. Single dose of nifedipine in normotensive pregnancy: nifedipine concentrations, hemodynamic responses, and uterine and fetal flow velocity waveforms. Obstet Gynecol 1990; 76: 807-811.
19. Rizzo G, Arduini D, Mancuso S, Romanini C. Effects of nifedipine on umbilical artery velocity waveforms in healthy human fetuses. Gynecol Obstet Invest 1987; 24: 151-154.
20. Mari G, Kirshon B, Moise KJ Jr, Lee W, Cotton DB. Doppler assessment of the fetal and uteroplacental circulation during nifedipine therapy for preterm labor. Am J Obstet Gynecol 1989; 161: 1514-1518.
21. Meyer WR, Randall HW, Graves WL. Nifedipine versus ritodrine for suppressing preterm labor. J Reprod Med 1990; 35: 649-653.
22. Garcia-Velasco JA, Gonzalez A. A prospective, randomized trial of nifedipine vs. ritodrine in threatened preterm labor. Int J Gynaecol Obstet 1998; 61: 239-244.