The effects of melatonin on focal cerebral ischemia-reperfusion model

Saudi Medical Journal

Volumn 25, Issue 11, 2004, Pages 1751-1752

  Kavakli, Ahmet ^a   Sahna, Engin ^a   Parlakpinar, Hakan ^b   Yahsi, Seyfettin ^a   Ogeturk, Murat ^a   Acet, Ahmet ^b  

^a FIRAT UNIVERSITY   (Turkey)

^b INONU UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

MELATONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; BODY TEMPERATURE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN NECROSIS; CELL VACUOLE; COMMON CAROTID ARTERY; CONTROLLED STUDY; DRUG MECHANISM; FOREBRAIN; HIPPOCAMPUS; HISTOPATHOLOGY; HYPEREMIA; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; RAT; REPERFUSION INJURY;

ANIMALS; BRAIN ISCHEMIA; CELL SURVIVAL; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MELATONIN; NECROSIS; NEURONS; NEUROPROTECTIVE AGENTS; PREMEDICATION; RATS; REPERFUSION INJURY;

EID: 10644226903     PISSN: 03795284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Chan PH. Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 2001; 21: 2-14.
2. Cho S, Joh TH, Baik HH, Dibinis C, Volpe BT. Melatonin administration protects CA1 hippocampal neurons after transient forebrain ischemia in rats. Brain Research 1997; 755: 335-338.
3. Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible Middle cerebral Artery Occlusion Without Craniectomy in Rats. Stroke 1989; 20: 84-91.
4. Pei Z, Pang SF, Cheung RT. Pretreatment with melatonin reduces volume of cerebral infarction in a rat middle cerebral artery occlusion stroke model. J Pineal Res 2002; 32: 168-172.
5. Gupta YK, Chaudhary G, Sinha K. Enhanced protection by melatonin and meloxicam combination in a middle cerebral artery occlusion model of acute ischemic stroke in rat. Can J Physiol Pharmacol 2002; 80: 210-217.
6. Torii K, Uneyama H, Nishino H, Kondoh T. Melatonin suppresses cerebral edema caused by middle cerebral artery occlusion/reperfusion in rats assessed by magnetic resonance imaging. J Pineal Res 2004; 36: 18-24.