Nonsyndromic inherited hearing impairment caused by mtDNA double mutations of A1555G and 961 insC

Chinese Journal of Medical Genetics

Volumn 21, Issue 6, 2004, Pages 629-632

  Cao, Xin ^a   Xing, Guang Qian ^a   Wei, Qin Jun ^a   Bu, Xing Kuan ^a   Wang, Deng Yuan ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Gene mutation; Mitochondrial DNA; Nonsyndromic inherited hearing impairment

Indexed keywords

MITOCHONDRIAL DNA; RIBOSOME RNA;

ARTICLE; CLINICAL ARTICLE; DNA EXTRACTION; DNA SEQUENCE; FEMALE; GENE AMPLIFICATION; GENE INSERTION; GENE MUTATION; GENE TARGETING; GENOTYPE; HEARING IMPAIRMENT; HEARING LOSS; HEARING TEST; HUMAN; LEUKOCYTE; MALE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PEDIGREE; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; VALIDATION PROCESS;

BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HEARING LOSS; HEARING LOSS, SENSORINEURAL; HUMANS; MALE; MUTAGENESIS, INSERTIONAL; PEDIGREE; POINT MUTATION;

INSERTION SEQUENCES;

EID: 10644224533     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

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3. Hutchin T. Sensorineural hearing loss and the 1555G mitochondrial DNA mutation. Acta Otolaryngol, 1999, 119: 48-52.
4. G mutation in patients with aminoglycoside antibiotic-induced deafness. Chin J Med Genet, 1999, 16: 141-144.
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7. Yoshida M, Shintani T, Hirao M, et al. Aminoglycoside-induced hearing loss in a patient with the 961 mutation in mtDNA. ORL J Otorhinolaryngol Relat Spec, 2002, 64: 219-222.