Differential expression of transforming growth factor-β, basic fibroblast growth factor, and their receptors in CD34+ hematopoietic progenitor cells from patients with myelofibrosis and myeloid metaplasia

Blood

Volumn 88, Issue 12, 1996, Pages 4534-4546

  Le Bousse Kerdilès, Marie Caroline ^a   Chevillard, Sylvie ^b   Charpentier, Agnès ^b   Romquin, Nicole ^b   Clay, Denis ^b   Smadja Joffe, Florence ^b   Praloran, Vincent ^b   Dupriez, Brigitte ^b   Demory, Jean Loup ^b   Jasmin, Claude ^b   Martyré, Marie Claire ^b  

^a HÔPITAL PAUL BROUSSE   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CD34 ANTIGEN; FIBROBLAST GROWTH FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ADULT; AGED; ARTICLE; CELL GROWTH; CELL SURVIVAL; CLINICAL ARTICLE; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MALE; MYELOFIBROSIS; MYELOID METAPLASIA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 10544255357     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.12.4534.bloodjournal88124534     Document Type: Article

References (58)

1. Ward HP, Block MH: The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with the myeloproliferative syndrome. Medicine 50:357, 1971
2. Battegay EJ, Thomssen C, Nissen C, Gudat F, Speck B: Endogenous megakaryocyte colonies from peripheral blood in precursor cell. Eur J Haematol 42:321, 1989
3. Chikkappa G, Carsten AL, Chanana AD, Chandra P, Cronkite EP: Increased granulocytic, erythrocytic and megakaryocytic progenitors in myelofibrosis with myeloid metaplasia. Am J Hematol 4:121, 1978
4. Douay L, Laporte JP, Lefrançois G, Najman A, Dupuy-Montbrun MC, Lopez M, Giarratana MC, Gorin NC: Blood and spleen haematopoiesis in patients with myelofibrosis. Leuk Res 8:725, 1978
5. Douer D, Fabian I, Cline MJ: Circulating pluripotent haemopoietic cells in patients with myeloproliferative disorders. Br J Haematol 54:373, 1983
6. Han ZC, Brière J, Nedellec G, Algrall JF, Sensobe L, Parent D, Guern G: Characteristics of circulating megakaryocyte progenitors (CFU-MK) in patients with primary myelofibrosis. Eur J Haematol 40:130, 1988
7. Hibbin JA, Njoku OS, Matutes E, Lewis SM, Goldman JM: Myeloid progenitor cells in the circulation of patients with myelofibrosis and other myeloproliferative disorders. Br J Haematol 57:495, 1984
8. Wolf BC, Neiman RS: Hypothesis: Splenic filtration and the pathogenesis of extramedullary hematopoiesis in agnogenic myeloid metaplasia. Hum Pathol 1:77, 1987
9. Buschle M, Janssen JWG, Drexler H, Lyons T, Anger B, Bartram CR: Evidence for pluripotent stem cell origin of idiopathic myelofibrosis: Clonal analysis of a case characterized by a N-ras gene mutation. Leukemia 2:658, 1988
10. Jacobson RJ, Salo A, Fialkow PJ: Agnogenic myeloid metaplasia: A clonal proliferation of haematopoietic stem cells with secondary myelofibrosis. Blood 51:189, 1978
11. Sato Y, Suda T, Suda J: Multilineage expression of haemopoietic precursors with abnormal clone in idiopathic myelofibrosis. Br J Haematol 64:657, 1986
12. Wang JC, Lang HD, Lichter S, Weinstein M, Benn P: Cytogenetic studies of bone marrow fibroblasts cultured from patients with myelofibrosis and myeloid metaplasia. Br J Haematol 80:184, 1992
13. Groopman JE: The pathogenesis of myelofibrosis in myeloproliferative disorders. Haematol Med 92:857, 1980
14. Castro-Malaspina H: Pathogenesis of myelofibrosis: Role of ineffective megakaryopoiesis and megakaryocyte components. Prog Clin Biol Res 154:427, 1984
15. Martyré, MC, Magdelenat H, Bryckaert MC, Laine-Bidron C, Calvo F: Increased intraplatelet levels of platelet-derived growth factor and transforming growth factor-β in patients with myelofibrosis with myeloid metaplasia. Br J Haematol 77:80, 1991
16. Martyre MC, Romquin N, Le Bousse-Kerdilès C, Chevillard S, Benyahia B, Dupriez B, Demory JL, Bauters F: Transforming growth factor-β and megakaryocytes in the pathogenesis of idiopathic myelofibrosis. Br J Haematol 88:9, 1994
17. Roberts AB, Sporn MB: The transforming growth factor-β, in Sporn MB, Roberts AB (eds): Peptide Growth Factors and Their Receptors, Handbook of Experimental Pharmacology. Heidelberg, Germany, Springer, 1990, p 419
18. Gospodarowicz D, Ferrara N, Schweigerer L, Neufeld G: Structural characterization and biological functions of fibroblast growth factor. Endocrine Rev 8:95, 1987
19. Massagué J: The transforming growth factor-β family. Annu Rev Cell Biol 6:597, 1990
20. Allouche M: Basic fibroblast growth factor and hematopoiesis. Leukemia 9:937, 1995
21. Allouche M, Bayard F, Clamens S, Fillola G, Sié P, Almaric F: Expression of basic fibroblast growth factor (bFGF) and FGF-receptors in human leukemic cells. Leukemia 9:77, 1995
22. Hino M, Tojo A, Miyazono K, Urabe A, Takaku F: Effects of type-β transforming growth factors on haematopoietic progenitor cells. Br J Haematol 70:143, 1988
23. Sing GK, Keller JR, Ellingsworth LR, Ruscetti FW: Transforming growth factor-β selectively inhibits normal and leukemic human bone marrow cell growth in vitro. Blood 72:1504, 1988
24. Hooper CW: The role of transforming growth factor-beta in hematopoiesis. A review. Leuk Res 15:179, 1991
25. Gabbianelli M, Sargiacomo M, Pelosi E, Testa U, Isacchi G, Peschle C: "Pure" human hematopoietic progenitors: Permissive action of basic fibroblast growth factor. Science 249:1561, 1990
26. Hatzfeld J, Li M, Brown EL, Sookdeo H, Levesque JP, O'Toole T, Gurney C, Clark SC, Hatzfeld A: Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor-β or Rb oligonucleotides. J Exp Med 174:925, 1991
27. Gabrilove JL, Wong G, Bollenbacher E, White K, Kojima S, Wilson EL: Basic fibroblast growth factor counteracts the suppressive effect of transforming growth factor-β on human myeloid progenitor cells. Blood 81:909, 1993
28. Gallicchio VS, Hughes NK, Hulette BC, DellaPuca R, Noblitt L: Basic fibroblast growth factor (bFGF) induces early and late-stage hematopoietic progenitor cell colony formation (CFU-gm, CFU-meg, and BFUe) by synergizing with GM-CSF, Meg-CSF, and erythropoietin, and is a radioprotective agent in vitro. Int J Cell Cloning 9:220, 1991
29. Gabrilove JL, White K, Rahman Z, Wilson EL: Stem cell factor and basic fibroblast growth factor are synergistic in augmenting committed myeloid progenitor cell growth. Blood 83:907, 1994
30. Wilson EL, Rifkin DB, Kelly F, Hannocks MJ, Gabrilove JL: Basic fibroblast growth factor stimulates myelopoiesis in long-term human bone marrow cultures. Blood 77:954, 1991
31. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
32. Debili N, Issaad C, Masse JM, Guichard J, Katz A, Breton-Gorius J, Vainchenker W: Expression of CD34 and platelet glycoproteins during human megakaryocytic differentiation. Blood 80:3022, 1992
33. Li M, Hatzfeld A, Brown EL, Sookdeo H, Panterne B, Levesque JP, O'Toole T, Clark SC, Hatzfeld J: Autocrine transforming growth factor-β controls Go phase of early human hematopoietic progenitors in serum- or serum-free culture, in Murphy MJ Jr (ed): Blood Cell Growth Factors. Proceedings of the Beijing Symposium. Dayton, OH, AlphaMed, 1991, p 228
34. Lardon F, Snoeck HW, Nijs G, Lenjou M, Peetermans ME, Rodrigus I, Berneman ZN, Van Bockstaele DR: Transforming growth factor-β regulates the cell cycle status of interleukin-3 (IL-3) plus IL-1, stem cell factor, or IL-6 stimulated CD34+ human hematopoietic progenitor cells through different cell kinetic mechanisms depending on the applied stimulus. Exp Hematol 22:903, 1994
35. Cashman JD, Eaves AC, Raines EW, Ross R, Eaves CJ: Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-β. Blood 75:96, 1990
36. Franzen P, ten Dijke P, Ichijo H, Yamashita H, Schulz P, Heldin CH, Miyazono K: Cloning of a TGF-β type I receptor that forms a heteromeric complex with the TGF-β type II receptor. Cell 75:681, 1993
37. Lin HY, Wang XF, Ng-Eaton E, Weinberg RA, Lodish HF: Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell 68:775, 1992
38. Wang XF, Lin HY, Ng-Eaton E, Downward J, Lodish HF, Weinberg RA: Expression cloning and characterization of the TGF-β type III receptor. Cell 67:797, 1991
39. Wrana JL, Attisano L, Wieser R, Ventura F, Massagué J: Mechanism of activation of the TGF-β receptor. Nature 370:341, 1994
40. Bender JG, Unverzagt KL, Walker DE, Lee W, Van Epps DE, Smith DH, Stewart CC, Bik To L: Identification and comparison of CD34-positive cells and their subpopulations from normal peripheral blood and bone marrow using multicolor flow cytometry. Blood 77:2591, 1991
41. Herbein G, Sovalat H, Wunder E, Baerenzung M, Bachorz J, Lewandowski H, Schweitzer C, Schmitt C, Kirn A, Hénon P: Isolation and identification of two CD34+ cell subpopulations from normal human peripheral blood. Stem Cells 12:187, 1994
42. + T cells. Proc Natl Acad Sci USA 91:2890, 1994
43. Ross R: The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 362:801, 1993
44. Brunner G, Nguyen H, Gabrilove JL, Rifkin DB, Wilson EL: Basic fibroblast growth factor expression in human bone marrow and peripheral blood cells. Blood 81:631, 1993
45. Avivi A, Zimmer Y, Yagon A, Yarden Y, Givol D: Flg-2, a new member of the family of fibroblast growth factor receptors. Oncogene 6:1089, 1991
46. Dionne CA, Crumley G, Bellot F, Kaplow JM, Searfoss G, Ruta M, Burgess WH, Jaye M, Schlessinger J: Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors. EMBO J 9:2685, 1990
47. Partanen J, Mäkelä TP, Alitalo R, Lehväslaiho H, Alitalo K: Putative tyrosine kinases expressed in K-562 human leukemia cells. Proc Natl Acad Sci USA 87:8913, 1990
48. Keegan K, Johnson DE, Williams LT, Hayman MJ: Isolation of an additional member of the fibroblast growth factor receptor family FGF R-3. Proc Natl Acad Sci USA 88:1095, 1991
49. Armstrong E, Vainikka S, Partanen J, Korhonen J, Alitalo R: Expression of fibroblast growth factor receptors in human leukemia cells. Cancer Res 52:2004, 1992
50. Bikfalvi A, Han ZC, Fuhrmann G: Interaction of fibroblast growth factor (FGF) with megakaryocytopoiesis and demonstration of FGF receptor expression in megakaryocytes and megakaryocytic-like cells. Blood 80:1905, 1992
51. Mignatti P, Rifkin DB: Release of basic fibroblast growth factor, and angiogenic factor devoid of secretory signal sequence: A trivial phenomenon or a novel secretion mechanism. J Cell Biochem 47:201, 1991
52. Abboud SL, Pinzani M: Peptide growth factors stimulate macrophage colony stimulating factor in murine stromal cells. Blood 78:103, 1991
53. Gilbert HS, Praloran V, Stanley ER: Increased CSF-1 (M-CSF) in myeloproliferative disease: Association with myeloid metaplasia and peripheral bone marrow extension. Blood 74:1231, 1989
54. Hasselbalch HC: Idiopathic myelofibrosis. Clinical aspects and studies on extracellular matrix metabolism. Danish Med Bull 40:39, 1993
55. Smadja-Joffe F, Legras S, Li Y, Girard N, Delpech B, Morimoto K, Le Bousse-Kerdilès C, Jasmin C, Levesque JP: CD44 and hyaluronan binding by human myeloid cells. Leuk Lymphoma 21:407, 1996
56. Fafeur V, Terman BI, Blum J, Böhlen P: Basic FGF treatment of endothelial cells down-regulates the 85-KDa TGF-β receptor subtype and decreases the growth inhibitory response to TGF-β. Growth Factors 3:237, 1990
57. Eaves AC, Cashman JD, Gaboury LA, Kalousek DK, Eaves CJ: Unregulated proliferation of primitive chronic myeloid leukemia progenitors in the presence of normal marrow adherent cells. Proc Natl Acad Sci USA 83:5306, 1986
58. Zauli G, Visani G, Catani L, Vianelli N, Gugliotta L, Capitani S: Reduced responsiveness of bone marrow megacaryocyte progenitors to platelet-derived transforming growth factor-β, produced in normal amount, in patients with essential thrombocythaemia. Br J Haematol 83:14, 1993