Molecular basis for lack of expression of HLA class I antigens in human small-cell lung carcinoma cell lines

International Journal of Cancer

Volumn 68, Issue 5, 1996, Pages 629-636

  Singal, Dharam P ^a   Ming, Y E ^a   Qiu, Xiaohong ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HLA ANTIGEN CLASS 1; TUMOR ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; PRIORITY JOURNAL; TUMOR CELL LINE; TUMOR IMMUNITY;

BASE SEQUENCE; CARCINOMA, SMALL CELL; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; TUMOR CELLS, CULTURED; TUMOR ESCAPE;

EID: 10544242200     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19961127)68:5<629::AID-IJC13>3.0.CO;2-X     Document Type: Article

References (24)

1. BLANCHET, O., BOURGE, J.F., ZINSZNER, H., ISRAEL, A., KOURILSKY, P., DAUSSET, J., DEGOS, L. and PAUL, P., Altered binding of regulatory factors to HLA class I enhancer sequence in human tumor cell lines lacking class I antigen expression. Proc. not. Acad. Sei. (Wash.), 89, 3488-3492(1992).
2. BUNCE, M., FANNING, G.C. and WELSH, K.I., Comprehensive, serologically equivalent DNA typing for HLA-B by PCR using sequencespecific primers (PCR-SSP). Tissue Antigens, 45, 81-90 (1995).
3. CARLOW, D.A., KERBEL, R.S. and ELLIOTT, B.E., Failure of expression of class I major histocompatibility antigens to alter tumor immunogenicity of a spontaneous murine carcinoma. J not. Cancer Inst., 81, 759-767 (1989).
4. CONNOR, M.E. and STERN, P.L., Loss of MHC class-I expression in cervical carcinomas. Int. J. Cancer, 46, 1029-1034 (1990).
5. CROMME, F.V., AIREY, J., HEEMELS, M.T., PLOEGH, H., KEATING, P.J., STERN, P.L., MEIJER, C.J.L.M. and WALBOOMERS, J.M.M., Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas. J. exp. Med., 179, 335-340 (1994).
6. DOYLE, A., MARTIN, W.J., FUNA, K., GAZDAR, A., CARNEY, D., MARTIN, S.E., LINNOILA, I., CUTTITTA, F., MULSHINE, J., BUNN, P. and MINNA, J., Markedly decreased expression of class I histocompatibility antigens, proteins, and mRNA in human small-cell lung cancer. J, exp. Med., 161, 1135-1151(1985).
7. FERRONE, S. and MARINCOLA, P.M., Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance. Immunol. Today, 16, 487-494(1995).
8. KAKLAMANIS, L., LEEK, R., KOUKOURAKIS, M., GATTER, K.C. and HARRIS, A.L., Loss of transporter in antigen processing 1 transporter protein and major histocompatibility complex class I molecules in metastatic versus primary breast cancer. Cancer Res., 55, 5191-5194 (1995).
9. KAKLAMANIS, L., TOWNSEND, A., DOUSSIS-ANAGNOSTOPOULOU, L.A., MORTENSEN, N., HARRIS, A.L. and GATTER, K.C., Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer. Amer. J. Path., 145, 05-509 (1994).
10. MöLLER, P., HERRMANN, B., MOLDENHAUER, G. and MOMBURG, F., Defective expression of MHC class I antigens is frequent in B-cell lymphomas of high-grade malignancy. Int. J. Cancer, 40, 32-39 (1987).
11. MOMBURG, F., ZIEGLER, A., HARPPRECHT, J., MöLLER, P., MOLDENHAUER, G. and HAMMERLING, G.J., Selective loss of HLA-A or HLA-B antigen expression in colon carcinoma. J. Immunol., 142, 352-358 (1989).
12. PATERSON, A.C., SCIOT, R., KEW, M.C., CALLEA, F., DUSHEIKO, G.M. and DESMET, V.J., HLA expression on human hepatocellular carcinoma. Brit. J. Cancer, 57, 369-373 (1988).
13. RESTIFO, N.P., ESQUIVEL, F., KAWAKAMI, Y., YEWDELL, J.W., MULE, J.J., ROSENBERG, S.A. and BENNINK, J.R., Identification of human cancers deficient in antigen processing. J. exp. Med., 177, 265-272 (1993).
14. SINGAL, D.P. and Qiu, X., Polymorphism in both X and Y box motifs controls level of expression of HLA-DRB1 genes. Immunogenetics, 43, 50-56 (1996).
15. SINGAL, D.P., YE, M., Ni, J. and SNIDER, O.P., Markedly decreased expression of TAPI and LMP2 genes in HLA class 1-deficient human tumor cell lines. Immunol. Letters, 50, 149-154 (1996).
16. SINGAL, D.P., YE, M. and QUADRI, S.A., Major histocompatibility-encoded human proteasome LMP2: genomic organization and a new form of mRNA.y. biol. Cliem., 270, 1966-1970(1995).
17. SMITH, M.E.F., MARSH, S.G.E., BOOMER, J.G., GELSTHORPE, K. and BOOMER, W.F., Loss of HLA-A, B, C allele products and lymphocyte function-associated antigen 3 in colorectal neoplasia. Proc. not. Acad. Sei. (Wash.), 86, 5557-5561 (1989).
18. SUMMER, C.W., HAMPSON, V.J. and TAYLOR, G.M., HLA class 1 non-coding nucleotide sequences. 1992. Europ. J. Imnnmogenet., 20, 201-240(1993).
19. TOWNSEND, A. and BOOMER, H., Antigen recognition by class I-restricted T lymphocytes. Ann. Rev. ImmunoL, 7, 601-624 (1989).
20. 2-microglobulin antigens in human choriocarcinoma cell lines. J, exp. Mcd., 152, 11-17 (1980).
21. VAN DEN INCH, H.F., RUITER, D.J., GRIFFIGEN, G., VAN MUIJEN, G.N.P. and FERRONE, S., HLA antigens in colorectal tumours-low expression of HLA class I antigens in mucinous colorectal carcinomas. Brit. J. Cancer, 55, 125-130 (1987).
22. WADEE, A.A., PATERSON, A., COPLAN, K.A. and REDDY, S.O., HLA expression in hepatocullar carcinoma cell lines, din. exp. ImmunoL, 97, 328-333 (1994).
23. WEISS, J.H. and SEIDMAN, J.G., The expression of major histocompatibility antigens under metallothionem gene promoter control. J. ImmunoL, 134, 1999-2003 (1985).
24. WRIGHT, K.L., WHITE, L.C., KELLY, A., BECK, S., TROWSDALE, J. and TING, J.P.Y., Coordinate regulation of the human TAPI and LMP2 genes from a shared bidirectional promoter. J. exp. Med., 181, 1459-1471 (1995).