The bone-marrow infiltration pattern in B-cell chronic lymphocytic leukemia is not an important prognostic factor

European Journal of Haematology

Volumn 57, Issue 4, 1996, Pages 292-300

  Geisler, C H ^a,b   Hou Jensen, K ^a   Jensen, O Myhre ^e   Tinggaard Pedersen, N ^d   Hansen, M Mørk ^a   Hansen, N E ^c   Holm, M ^e   Christensen, B Egelund ^d   Drivsholm, A ^a   Nielsen, J Boye ^a   Thorling, K ^e   Andersen, E ^f   Larsen, J K ^b   Andersen, P Kragh ^g  

^a Rigshospitalet   (Denmark)

^b FINSEN LABORATORY   (Denmark)

^c GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^d ODENSE UNIVERSITY HOSPITAL   (Denmark)

^e AARHUS UNIVERSITY HOSPITAL   (Denmark)

^f VIBORG HOSPITAL   (Denmark)

^g UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

B CLL; bone marrow histology; clinical stage; immunophenotype; prognosis

Indexed keywords

CD5 ANTIGEN; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; DOXORUBICIN; PREDNISOLONE; VINCRISTINE;

ADULT; AGED; ARTICLE; B CELL LEUKEMIA; BONE MARROW METASTASIS; CANCER STAGING; CHRONIC LYMPHATIC LEUKEMIA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS;

EID: 10544237684     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0609.1996.tb01380.x     Document Type: Article

References (28)

1. GRAY JL, JACOBS A, BLOCK M. Bone marrow and peripheral blood lymphocytosis in the prognosis of chronic lymphocytic leukemia. Cancer 1974: 33: 1169-1178.
2. LIPSHUTZ MD, MIR R, RAI KR, SAWITSKY A. Bone marrow biopsy and clinical staging in chronic lymphocytic leukemia. Cancer 1980: 46: 1422-1427.
3. ROZMAN C, HERNANDEZ-NIETO L, MONTSERRAT E, BRUGUES R. Prognostic significance of bone-marrow patterns in chronic lymphocytic leukaemia. Br J Haematol 1981: 47: 529-537.
4. ROZMAN C, MONTSERRAT E, RODRIGUEZ-FERNANDEZ JM, et al. Bone marrow histologic pattern - the best single prognostic parameter in chronic lymphocytic leukemia: a multivariate analysis of 329 cases. Blood 1984: 64: 642-648.
5. BARTL R, FRISCH B, BURKHARDT R, HOFFMANN-FEZER G, DEMMLER K, SUND M. Assessment of marrow trephine in relation to staging in chronic lymphocytic leukaemia. Br J Haematol 1982: 51: 1-15.
6. HAN T, BARCOS M, EMRICH L, et al. Bone marrow infiltration patterns and their prognostic significance in chronic lymphocytic leukemia; correlations with clinical, immunologic, phenotypic, and cytogenetic data. J Clin Oncol 1984: 2: 562-750.
7. GEISLER CH, RALFKIÆR E, MORK HANSEN M, HOU-JENSEN K. The bone marow histological pattern has independent prognostic value in early stage chronic lymphocytic leukaemia. Br J Haematol 1986: 62: 47-54.
8. PANGALIS GA, ROUSSOU PA, KITTAS C, KOKKINOU S, FESSAS P. B-chronic lymphocytic leukemia. Prognostic implication of bone marrow histology in 120 patients. Experience from a single hematology unit. Cancer 1987: 59: 767-771.
9. MAURO FR, DE ROSSI G, BURGIO VL, et al. Prognostic value of bone marrow histology in chronic lymphocytic leukemia. A study of 335 cases from a single institution. Haematologica 1994: 79: 334-341.
10. BINÉT JL, CATOVSKY D, CHANDRA P, MONTSERRAT E, RAI K, SAWITSKY A (writing committee of the International Workshop on CLL). Chronic lymphocytic leukaemia: proposals for a revised staging system. Br J Haematol 1981: 48: 365-367.
11. GEISLER CH, LARSEN, JK, HANSEN NE, et al. Prognostic importance of flow cytometric immunophenotyping of 540 consecutive patients with B-cell chronic lymphocytic leukemia. Blood 1991: 78: 1795-1802.
12. GEISLER CH, PHILIP P, HANSEN MM. B-cell chronic lymphocytic leukaemia: clonal chromosome abnormalities and prognosis in cases. Eur J Haematol 1989: 43: 397-403.
13. HANSEN MM, ANDERSEN E, CHRISTENSEN BE, et al. CHOP versus prednisolone+chlorambucil in chronic lymphocytic leukemia. Leuk and Lymph 1991 (suppl.): 97-100.
14. BARTL R, FRISCH B, BURKHARDT R, JÄGER K, PAPENBERGER R, HOFFMAN-FEZER G. Lymphoproliferations in the bone marrow: identification and evolution; classification and staging. J Clin Pathol 1984: 37: 233-254.
15. KAPLAN E, MEIER E. Non-parametric estimations from incomplete observations. J Am Stat Ass 1958: 153: 457-481.
16. PETO R, PIKE MC, ARMITAGE P, et al. Design and analysis of randomized clinical trials requiring prolonged observations of each patient: II. Analysis and examples. Br J Cancer 1977: 35: 1-39.
17. Cox DR. Regression models and life tables. J R Stat Soc B 1972: 34: 187-220.
18. BENNETT JM, CATOVSKY D, DANIEL MT, FLANDRIN G, GALTON DAG, GRALNICK HR, SULTAN C. The French-American-British (FAB) cooperative group. Proposals for the classification of chronic (mature) B and T lymphoid leukaemias. J Clin Pathol 1989: 42: 657-684.
19. ORFAO A, GONZALEZ M, SAN MIGUEL J, et al. Bone Marrow histopathologic patterns and immunologic phenotype in B-cell chronic lymphocytic leukaemia. Blut 1988: 57: 19-23.
20. DHODAPKAR M, TEFFERI A, SU J, PHYLLIKY L. Prognostic features and survival in young adults with early/intermediate chronic lymphocytic leukemia (B-CLL): a single institution study. Leukemia 1993: 7: 1232-1235.
21. WARNKE RA, KIM H, FUKS Z, DORFMAN RF. The coexistence of nodular and diffuse patterns in nodular non-Hodgkin's lymphomas. Cancer 1977: 40: 1229-1233.
22. BINET JL, LEPORRIER M, DIGHIERO G, et al. A clinical staging system for chronic lymphocytic leukemia. Cancer 1977b: 40: 855-864.
23. PANGALIS GA, BOUSIOTIS VA, KITTAS C. B-chronic lymphocytic leukemia. Disease progression in 150 untreated stage A and B patients as predicted by bone marrow pattern. Nouv Rev Hematol Fr 1988: 30: 373-375.
24. FRENCH COOPERATIVE GROUP ON CHRONIC LYMPHOCYTIC LEUKEMIA. Natural history of stage A chronic lymphocytic leukaemia untreated patients. Br J Haematol 1990: 76: 45-57.
25. RAI KR, SAWITSKY A, CRONKITE EP, CHANANA AD, LEVY RN, PASTERNACK BS. Clinical staging of chronic lymphocytic leukemia. Blood 1975: 46: 219-234.
26. MONTSERRAT E, VINOLAS N, REVERTER JC, ROZMAN C. Natural history of chronic lymphocytic leukemia: on the progression and prognosis of early clinical stage. Nouv Rev Fr Haematol 1988: 30: 359-361.
27. FRENCH COOPERATIVE GROUP ON CHRONIC LYMPHOCYTIC LEUKEMIA. Effects of chlorambucil and therapeutic decision in initial forms of chronic lymphocytic leukemia (stage A): results of a randomized trial on 612 patients. Blood 1990: 75: 1414-1421.
28. BRUGIATELLI, JAKSIC B, PLANINC-PERAICA A, et al. Treatment of chronic lymphocytic leukemia in in early and stable phase: long-term results of a randomized trial. Eur J Haematol 1995: 55: 158-163.