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Volumn 2, Issue 11, 1996, Pages 1819-1824

High-Dose edatrexate with oral leucovorin rescue: A phase I and clinical pharmacological study in adults with advanced cancer

Author keywords

[No Author keywords available]

Indexed keywords

EDATREXATE; FOLINIC ACID;

EID: 10544232609     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (2)

References (16)
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  • 2
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    • New folate analogs of the 10-deaza-aminopterin series. Markedly increased activity of the 10-ethyl analogue compared to the parent compound and methotrexate against some human tumor xenografts in nude mice
    • Schmid, F. A., Sirotnak, F. M., and Otter, G. M. New folate analogs of the 10-deaza-aminopterin series. Markedly increased activity of the 10-ethyl analogue compared to the parent compound and methotrexate against some human tumor xenografts in nude mice. Cancer Treat. Rep., 69: 551-553, 1985.
    • (1985) Cancer Treat. Rep. , vol.69 , pp. 551-553
    • Schmid, F.A.1    Sirotnak, F.M.2    Otter, G.M.3
  • 3
    • 0021328814 scopus 로고
    • New folate analogues of the 10-deaza-aminopterin series. Basis for structural design and biochemical and pharmacologic properties
    • Sirotnak, F. M., DeGraw, J. I., Moccio, D. M., Samuels, L. L., and Goutas, L. J. New folate analogues of the 10-deaza-aminopterin series. Basis for structural design and biochemical and pharmacologic properties. Cancer Chemother. Pharmacol., 12: 18-25, 1984.
    • (1984) Cancer Chemother. Pharmacol. , vol.12 , pp. 18-25
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  • 5
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    • Phase II study of 10-ethyl-10-deaza-aminopterin in patients with stage III and IV non-small cell lung cancer
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    • Shum, K.1    Kris, M.2    Gralla, R.3    Burke, T.4    Marks, L.5    Heelau, R.6
  • 6
    • 0025032334 scopus 로고
    • Phase II study of 10-ethyl-10-deaza-aminopterin (10-EdAM; CGP 30 694) for stage IIIb or IV non-small cell lung cancer
    • Lee, J. S., Libshitz, H. I., Murphy, W. K., Dhingra, H. M., Shirinian, M., Holoye, P. Y., and Hong. W. K. Phase II study of 10-ethyl-10-deaza-aminopterin (10-EdAM; CGP 30 694) for stage IIIb or IV non-small cell lung cancer. Invest. New Drugs, 8: 299-304, 1990.
    • (1990) Invest. New Drugs , vol.8 , pp. 299-304
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  • 7
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    • Markedly improved efficacy of edatrexate compared to methotrexate in a high-dose regimen and leucovorin rescue against metastatic murine solid tumors
    • Sirotnak, F. M., Otter, G. M., and Schmid, F. A. Markedly improved efficacy of edatrexate compared to methotrexate in a high-dose regimen and leucovorin rescue against metastatic murine solid tumors. Cancer Res., 53: 587-591, 1993.
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    • Sirotnak, F.M.1    Otter, G.M.2    Schmid, F.A.3
  • 8
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.