Hemostatic effect of activated recombinant factor VIIa in Bernard-Soulier syndrome: Studies in an in vitro model [1]

Transfusion

Volumn 44, Issue 12, 2004, Pages 1790-1791

  Tonda, Raúl ^a   Galán, Ana María ^a   Pino, Marcos ^a   Lozano, Miguel ^a   Ordinas, Antonio ^a   Escolar, Ginés ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DALTEPARIN; FIBRIN; LOW MOLECULAR WEIGHT HEPARIN; RECOMBINANT BLOOD CLOTTING FACTOR 7A; THROMBIN;

BERNARD SOULIER DISEASE; DRUG EFFICACY; HEMOSTASIS; HUMAN; IN VITRO STUDY; LETTER; MORPHOMETRICS; THROMBOCYTE AGGREGATION;

BERNARD-SOULIER SYNDROME; FACTOR VIIA; FIBRIN; HEMOSTATICS; HUMANS; PLATELET ACTIVATION; RECOMBINANT PROTEINS;

EID: 10444261161     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0041-1132.2004.00439.x     Document Type: Letter

References (8)

1. Galán AM, Tonda R, Altisent C, Maragall S, Ordinas A, Escolar G. Recombinant factor VIIa (Novoseven) restores deficient coagulation: experience from an ex vivo model. Semin Hematol 2001;38(4 Suppl 12):10-4.
2. Hedner U, Erhardtsen E. Potential role for rFVIIa in transfusion medicine. Transfusion 2002;42:114-24.
3. Poon MC, d'Oiron R. Recombinant activated factor VII (NovoSeven) treatment of platelet-related bleeding disorders. International Registry on Recombinant Factor VIIa and Congenital Platelet Disorders Group. Blood Coagul Fibrinolysis 2000;11(Suppl 1):S55-S68.
4. Galán AM, Tonda R, Pino M, et al. Increased local procoagulant action: a mechanism contributing to the favorable hemostatic effect of recombinant FVIIa in PLT disorders. Transfusion 2003;43:885-92.
5. Tonda R, Galan AM, Pino M, et al. Hemostatic effect of activated recombinant factor VII (rFVIIa) in liver disease: studies in an in vitro model. J Hepatol 2003;39:954-9.
6. Dale GL, Friese P, Batar P, et al. Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface. Nature 2002;415:175-9.
7. Kjalke M, Monroe DM, Hoffman M, et al. Active site-inactivated factors VIIa, Xa, and IXa inhibit individual steps in a cell-based model of tissue factor-initiated coagulation. Thromb Haemost 1998;80:578-84.
8. Hoffman M, Monroe DM. A cell-based model of hemostasis. Thromb Haemost 2001;85:958-65.