Involvement of signal transduction cascade via dopamine-D1 receptors in phencyclidine dependence

Annals of the New York Academy of Sciences

Volumn 1025, Issue , 2004, Pages 62-68

  Noda, Yukihiro ^a   Nabeshima, Toshitaka ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Catecholamine biosynthetic pathway; Conditioned place preference; Cyclic AMP pathway; Dopamine D1; Phencyclidine (PCP); Receptors; Reward

Indexed keywords

2 BROMO N (2 CHLOROETHYL) N ETHYLBENZYLAMINE; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR BLOCKING AGENT; MESSENGER RNA; NEUROTOXIN; OXIDOPAMINE; PHENCYCLIDINE; PROTEIN C FOS; SULPIRIDE; TYROSINE 3 MONOOXYGENASE;

CONFERENCE PAPER; DOPAMINERGIC ACTIVITY; DRUG ABUSE; HETEROZYGOSITY; NUCLEUS ACCUMBENS; SIGNAL TRANSDUCTION; WILD TYPE;

EID: 10444232043     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1316.008     Document Type: Conference Paper

References (25)

1. PETERSEN, R.C. & R.C. STILLMAN. 1978. Phencyclidine: an overview. NIDA Res. Monogr. 21: 1-17.
2. SCHECHTER, M.D. & D.J. CALCAGNETTI. 1993. Trends in place preference conditioning with a cross-indexed bibliography; 1957-1991. Neurosci. Biobehav. Rev. 17: 21-41.
3. ACQUAS, F. et al. 1989. SCH23390 blocks drug-conditioned place preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine-receptor blockade? Psychopharmacology 99: 151-155.
4. KITAICHI, K. et al. 1996. Acute phencyclidine induces aversion, but repeated phencyclidine induces preference in the place conditioning test in rats. Eur. J. Pharmacol. 318: 7-9.
5. KITAICHI, K. et al. 1999. Involvement of the serotonergic neuronal system in phencyclidine-induced place aversion in rats. Behav. Brain Res. 103: 105-111.
6. NODA, Y. et al. 1998. Involvement of dopaminergic system in phencyclidine-induced place preference in mice pretreated with phencyclidine repeatedly. J. Pharmacol. Exp. Ther. 286:44-51.
7. KOBAYASHI, K. et al. 1995. Targeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice. J. Biol. Chem. 270: 27235-27243.
8. KOOB, G.F. & F.E. BLOOM. 1988. Cellular and molecular mechanisms of drug dependence. Science 242: 715-723.
9. WISE, R.A. & M.A. BOZARTH. 1987. A psychomotor stimulant theory of addiction. Psychol. Rev. 94: 469-492.
10. DI CHIARA, G. & A. IMPERATO. 1988. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl. Acad. Sci. USA 85: 5274-5278.
11. ISSACS, S.P. et al. 1986. Phencyclidine (PCP) abuse. Oral Surg. Oral Med. Oral Pathol. 61: 126-129.
12. NABESHIMA, T. et al. 1987. Development of tolerance and supersensitivity to phencyclidine in rats after repeated administration of phencyclidine. Eur. J. Pharmacol. 135: 23-33.
13. LEONE, P. & G.D. DICHIARA. 1987. Blockade D-1 receptors by SCH-23390 antagonizes morphine and amphetamine-induced place preference conditioning. Eur. J. Pharmacol. 134: 251-254.
14. HEMBY, S.E. et al. 1994. Assessment of the relative contribution of peripheral and central components in cocaine place conditioning. Pharmacol. Biochem. Behav. 47: 973-979.
15. 3H]serotonin uptake in synaptosomal preparations from rat brain. Biochem. Pharmacol. 26: 1435-1439.
16. BOWYER, J.F. et al. 1984. Effects of phencyclidine, amphetamine and related compounds on dopamine release from and uptake into striatal synaptosomes. J. Pharmacol. Exp. Ther. 229: 671-680.
17. BRISTOW, L.J. et al. 1993. The glycine/NMDA receptor antagonist, R-(+)-HA-966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK-801) in rodents. Br. J. Pharmacol. 108: 1156-1163.
18. HONDO, H. et al. 1994. Effect of phencyclidine on dopamine release in the rat prefrontal cortex; an in vivo microdialysis study. Brain Res. 633: 337-342.
19. KITAICHI, K. et al. 1995. Risperidone prevents the development of supersensitivity, but not tolerance, to phencyclidine in rats treated with subacute phencyclidine. Life Sci. 56: 531-543.
20. DREW, K.L. & S.D. GLICK. 1990. Role of D-1 and D-2 receptor stimulation in sensitization to amphetamine-induced circling behavior and in expression and extinction of the Pavlovian conditioned response. Psychopharmacology 101: 465-471.
21. UJIKE, H. et al. 1991. Lasting increase in D1 dopamine receptors in the lateral part of the substantia nigra pars reticulata after subchronic methamphetamine administration. Brain Res. 540: 159-163.
22. NGUYEN, T.V. et al. 1992. Differential expression of c-fos and zif268 in rat striatum after haloperidol, clozapine, and amphetamine. Proc. Natl. Acad. Sci. USA 89: 4270-4274.
23. LJUNGBERG, T. & U. UNGERSTEDT. 1978. Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: evidence for two different mechanisms of action. Psychopharmacology 56: 239-247.
24. BREESE, G.R. et al. 1985. Dopamine agonist-induced locomotor activity in rats treated with 6-hydroxydopamine at differing ages: functional supersensitivity of D-1 dopamine receptors in neonatally lesioned rats. J. Pharmacol. Exp. Ther. 234: 447-455.
25. NESTLER, E.J. 1992. Molecular mechanisms of drug addiction. J. Neurosci. 12: 2439-2450.