KMD 3213: KAD 3213, silodosin

Drugs in R and D

Volumn 5, Issue 1, 2004, Pages 50-51

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1A ADRENERGIC RECEPTOR; PRAZOSIN; SILODOSIN; TAMSULOSIN;

ARTICLE; CLINICAL TRIAL; DISEASE ASSOCIATION; DRUG ABSORPTION; DRUG APPROVAL; DRUG MARKETING; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DYSURIA; HUMAN; INTESTINE ABSORPTION; NONHUMAN; PRIORITY JOURNAL; PROSTATE HYPERTROPHY; RAT; URETHRA PRESSURE;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; DRUGS, INVESTIGATIONAL; HUMANS; INDOLES; MALE; PROSTATIC HYPERPLASIA; URINATION DISORDERS;

EID: 1042304275     PISSN: 11745886     EISSN: None     Source Type: Journal    
DOI: 10.2165/00126839-200405010-00011     Document Type: Article

References (4)

1. Shibata K. Foglar R, Horie K. KMD-3213, a novel, potent, alpha-1a-adrenoceptor-selective antagonist: characterization using recombinant human alpha-1-adrenoceptors and native tissues. Molecular Pharmacology 48: 250-258, Aug 1995
2. Yamada S, Ohkura T. Nakajima M. In vitro and in vivo characterization of [3H]KMD-3213 binding to alpha-1-adrenoceptors in rat tissues. Japanese Journal of Pharmacology 79 (Suppl. 1): 130, 1999
3. Akiyama K, Hora M, Tatemichi S. KMD-3213, a uroselective and long-acting alpha 1a-adrenoceptor antagonist, tested in a novel rat model. Journal of Pharmacology and Experimental Therapeutics 291: 81-91, Oct 1999
4. Akiyama K, Noto H, Nishizawa O, et al. Effect of KMD-3213, an alpha(1A)-adrenoceptor antagonist, on the prostatic urethral pressure and blood pressure in male decerebrate dogs. International Journal of Urology 8: 177-183, Apr 2001