A New HPLC Method to Determine Glomerular Filtration Rate and Effective Renal Plasma Flow in Conscious Dogs by Single Intravenous Administration of Iohexol and p-Aminohippuric Acid

Journal of Chromatographic Science

Volumn 42, Issue 2, 2004, Pages 107-111

  Meucci, V ^a   Gasperini, A ^a   Soldani, G ^a   Guidi, G ^a   Giorgi, M ^a  

^a Veterinary Clinics Department   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBENZOIC ACID; 4 AMINOHIPPURIC ACID; IOHEXOL; IOPENTOL; METHANOL; SODIUM DIHYDROGEN PHOSPHATE; TETRABUTYLAMMONIUM;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; DOG; FLOW RATE; GLOMERULUS FILTRATION RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY CLEARANCE; KIDNEY PLASMA FLOW; MALE; NONHUMAN; PH; REPRODUCIBILITY;

ANIMALIA; CANIS FAMILIARIS; GLOMERULUS;

EID: 1042301284     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/42.2.107     Document Type: Article

References (15)

1. F. Gaspari, N. Perico, and G. Remuzzi. Measurement of glomerular filtration rate. Kidney Int. 52: S151-54 (1997).
2. S.A. Brown, D.R. Finco, F.D. Boudinot, J. Wright, S.L. Tarver, and T. Cooper. Evaluation of a single injection method, using iohexol, for estimating glomerular filtration rate in cats and dogs. Am. J. Vet. Res. 57: 105-10 (1996).
3. A. Gleadhill and A.R. Michell. Evaluation of iohexol as a marker for the clinical measurement of glomerular filtration rate. Res. Vet. Sci. 60: 117-21 (1996).
4. M. Nesje, A. Flaoyen, and L. Moe. Estimation of glomerular filtration rate in normal sheep by disappearance of iohexol from serum. Vet. Res. Comm. 21: 29-35 (1997).
5. F. Gaspari, N. Perico, M. Matalone, O. Signorini, N. Azzolini, M. Mister, and G. Remuzzi. Precision of plasma clearance of iohexol for estimation of GFR in patients with renal disease. J. Am. Soc. Nephrol. 9: 310-13 (1998).
6. R.G. Narins, G.G. Krishna, and L.J. Riley. "Assessment of renal function: characteristics of the functional and organic forms of acute renal failure." The Kidney: Physiology and Pathophysiology, 2nd ed. D.W. Seldin and G. Giebisch, Eds. Raven press, New York, NY, 1992, pp. 3063-84.
7. D.D. Maki, J.Z. Ma, T.A. Louis, and B.L. Kasiske. Long-term effects of anthypertensive agents on proteinuria and renal function. Arch. Int. Med. 155: 1073-80 (1995).
8. J. Edelson, G. Palace, and G. Park. High-performance liquid chromatographic determination of iohexol in plasma, urine and feces. J. Chromatogr. 274: 428-33 (1983).
9. P.B. Jacobsen. High performance liquid chromatography with multi-wavelength detection: a technique for identification of iodinated x-ray contrast agents in human body fluids and brain tissue. Am. J. Neuroradiol. 13: 1521-25 (1992).
10. L.R. Snyder, J.L. Glajch, and J.J. Kirkland. Practical HPLC Method Development. John Wiley, New York, NY, 1988, pp. 35-60.
11. T. Jacobsen. The preclinical development of iohexol (Omnipaque): a new X-ray contrast medium. Farmakoterapi 38: 45-77 (1982).
12. Food and Drug Administration. Reviewer Guidance: Validation of Chromatographic Methods. Center for Drug Evaluation and Research (CDER). http://www.fda.gov/cder/guidance/cmc3/pdf (accessed November, 1994).
13. V. Laroute, H.P. Lefebvre, G. Costes, and P.L. Toutain. Measurement of glomerular filtration rate and effective renal plasma flow in the conscious beagle dog by single intravenous bolus of iohexol and p-aminohippuric acid. J. Pharmacol. Toxicol. 41: 17-25 (1999).
14. B. Frennby and G. Sterner. Contrast media as marker of GFR. Eur. Radiol. 12: 475-84 (2002).
15. M. Haller, W. Muller, H. Binder, W. Estelberg, and P. Arnold. Single-injection inulin clearance - a simple method for measuring glomerular filtration rate in dogs. Res. Vet. Sci. 64: 151-56 (1998).