Apoptosis by 6-O-palmitoyl-L-ascorbic acid coincides with JNK-phosphorylation and inhibition of Mg2+-dependent phosphatase activity

Biochemical Pharmacology

Volumn 67, Issue 5, 2004, Pages 919-926

  Kaap, S ^a,b   Brechlin, P ^a   Quentin, I ^a   Eger, K ^b   Steinfelder, H J ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

6 O Palmitoyl ascorbic acid; Caspase activation; DNA fragmentation; JNK phosphorylation; JNK inhibitor SP600125; Phosphatase inhibition

Indexed keywords

ASCORBIC ACID; ASCORBIC ACID 6 PALMITATE; ASCORBIC ACID DERIVATIVE; CASPASE 3; DNA FRAGMENT; MAGNESIUM ION; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE 2C; SERINE; STRESS ACTIVATED PROTEIN KINASE; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CHEMICAL ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG TOLERABILITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; LC 50; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TIME; TUMOR CELL;

EID: 1042298766     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2003.10.001     Document Type: Article

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