Ethanol evolution rate: A new parameter to determine the feeding rate for the production of avermectins by Streptomyces avermitilis

Biotechnology Letters

Volumn 26, Issue 2, 2004, Pages 109-113

  Chen, Jie ^a   Zhang, Siliang ^a   Chu, Ju ^a   Zhuang, Yingping ^a   Luo, Jiali ^b   Bai, Hua ^b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Zhejiang Hisun Pharmaceutical Co Ltd   (China)

Author keywords

Avermectins; Ethanol evolution rate; Feeding; Glucose; Streptomyces avermitilis

Indexed keywords

ALCOHOL; AVERMECTIN; DRUG DERIVATIVE; GLUCOSE; IVERMECTIN; OXYGEN;

ARTICLE; CHEMISTRY; CULTURE MEDIUM; METABOLISM; STREPTOMYCES;

CULTURE MEDIA; ETHANOL; GLUCOSE; IVERMECTIN; OXYGEN; STREPTOMYCES;

STREPTOMYCES; STREPTOMYCES AVERMITILIS;

EID: 1042291447     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:BILE.0000012887.12874.fb     Document Type: Article

References (5)

1. Burg RW, Miller BM, Baker EE, Birnbaum J, Currie SA, Hartman R, Kong YL, Monaghan RL, Olson G, Putter I, Tunac JB, Wallick H, Stapley EO, Õiwa R, Õmura S (1979) Avermectins, new family of potent anthelmintic agents: producing oganism and fermentation. Antimicrob. Agents Chemother. 15: 361-367.
2. Cane DE, Liang TC, Kaplan LK, Nallin MK, Schulman MD, Hensens OD, Douglas AW, Albers-Schönberg G (1983) Biosynthesis origin of the carbon skeleton and oxygen atoms of the avermectins. J. Am. Chem. Soc. 105: 4110-4112.
3. Ikeda H, Õmura S (1995) Control of avermectin biosynthesis in Streptomyces avermitilis for the selective production of a useful component. J. Antibiot. 48: 548-562.
4. Ikeda H, Kotaki H, Tanaka H, Õmura S (1988) Involvement of glucose catabolism in avermectin production by Streptomyces avermitilis. Antimicrob. Agents Chemother. 32: 282-284.
5. Schulman MD, Valentino D, Hensens OD (1986) Biosynthesis of the avemectins by Streptomyces avermitilis: incorporation of labeled precursors. J. Antibiot. 39: 541-549.