Novel bisindole derivatives of Catharanthus alkaloids with potential cytotoxic properties

Advances in Experimental Medicine and Biology

Volumn 527, Issue , 2003, Pages 643-646

  Ruszkowska, Joanna ^a   Chrobak, Robert ^b   Wróbel, Jerzy T ^b   Czarnocki, Zbigniew ^b  

^a UNIVERSITY OF WARSAW   (Poland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; ANTINEOPLASTIC AGENT; CATHARANTHINE; CATHARANTHUS ROSEUS EXTRACT; INDOLE DERIVATIVE; LOGANINE; PLANT EXTRACT; TRYPTOPHAN; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE; VINDOLINE;

ANTINEOPLASTIC ACTIVITY; BIOSYNTHESIS; CATHARANTHUS ROSEUS; CONFERENCE PAPER; CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG SYNTHESIS; POLAND; PRIORITY JOURNAL; QUANTUM YIELD; SOLID PHASE EXTRACTION;

CATHARANTHUS; CATHARANTHUS ROSEUS;

EID: 1042291113     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0135-0_74     Document Type: Conference Paper

References (5)

1. Antitumor Bisindole Alkaloids from Catharanthus roseus (L) and ref cited, The Alkaloids, A. Brossi (Ed.), Vol. 37, Academic Press, New York, 1990.
2. R.J. Parry, The Biosynthesis of Catharanthus Alkaloids pp. 141-191 in W.I. Taylor, N.R. Farnsworth (Eds.) The Catharanthus Alkaloids, Marcel Dekker, New York, 1975.
3. J. Ruszkowska, B. Macierewicz, J.T. Wróbel, Sposób otrzymywania alkaloidow bisindolowych o działaniu cytostatycznym, P. 162 944 (C 07D 519/04), 31.01. 1994.
4. J. Ruszkowska, E. Lipkowska, J. Lipkowski, Estimation of Oncolytic Catharanthus Bisindoles by Means of Solid Phase Extraction (SPE) and HPLC Methods Seminar on Taxoids: Sources and Biological, Chemical and Pharmacological Aspects, The Medical University of Warsaw, June 24-25 1998, Warsaw, Poland.
5. I. Tabakovic, K. Tabakovic, One Pot Electrochemical Synthesis of 10.10′-Bisvindoline by an Oxidation-Reduction Sequence, Tetrahedron Lett. 37, 3659-3662 (1996).