Modern concepts in pharmacokinetics of intravenous anesthetic agents;Moderne Konzepte der Pharmakokinetik intravenöser Anästhetika

Anaesthesist

Volumn 53, Issue 1, 2004, Pages 95-110

  Heidegger, T ^a   Minto, C F ^b   Schnider, T W ^a  

^a Inst fur Anasthesiologie   (Switzerland)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Compartment model; Contextsensitive half time; Effect site compartment; IV anesthetics; Offset; Onset; Pharmacokinetics; Target controlled infusion (TCI) systems

Indexed keywords

ANESTHETIC AGENT; FENTANYL; MIDAZOLAM; PROPOFOL; REMIFENTANIL;

ANESTHESIA; ANESTHESIST; COMPUTER PROGRAM; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFECT; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INFUSION; MATHEMATICAL MODEL; PREDICTION; REVIEW;

ALGORITHMS; ANESTHESIA, INTRAVENOUS; ANESTHETICS, INTRAVENOUS; HUMANS; MODELS, THEORETICAL;

EID: 1042279480     PISSN: 00032417     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00101-003-0628-2     Document Type: Review

References (30)

1. Alvis JM, Reves JG, Govier AV et al. (1985) Computer-assisted continuous infusions of fentanyl during cardiac anesthesia: comparison with a manual method. Anesthesiology 63:41-49
2. Ausems ME, Stanski DR, Hug CC (1985) An evaluation of the accuracy of pharmacokinetic data for the computer assisted infusion of alfentanil. Br J Anaesth 57:1217-1225
3. Bailey JM, Shafer SL (1991) A simple analytical solution to the three-compartment pharmacokinetic model suitable for computer-controlled infusion pumps. IEEE Transactions in Biomedical Engineering 38:522-525
4. Bailey JM (1997) Context-sensitive half-times and other decrement times of inhaled anesthetics. Anesth Analg 85:681-686
5. Bailey JM (1995) Technique for quantifying the duration of intravenous anesthetic effect. Anesthesiology 83:1095-1103
6. Gentilini A, Frei CW, Glattfelder AH et al. (2000) Identification and targeting policies for computer-controlled infusion pumps. Crit Rev Biomed Eng 28:179-185
7. Henthorn TK, Avram MJ, Krejcie TC et al. (1992) Minimal compartmental model of circulatory mixing of indocyanine green. Am J Physiolol 262:903-910
8. Hughes MA, Glass PS, Jacobs JR (1992) Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs. Anesthesiology 76:334-341
9. Hull CJ, Van Beem HB, McLeod K et al. (1978) A pharmacodynamic model for pancuronium. Br J Anaesth 50:1113-1123
10. Jacobs JR (1990) Algorithm for optimal linear model-based control with application to pharmacokinetic mo0del-driven drug delivery. IEEE Trans Biomed Eng 37:107-109
11. Jacobs JR (1998) Analytical solution to the three-compartment pharmacokinetic model. IEEE Trans Biomed Eng 35:763-765
12. Mapleson WW (1984) Pharmacokinetics of inhaled anaesthetics. In: Prys-Roberts C, Hug CC Jr (eds) Pharmacokinetics of anaesthesia. Blackwell Scientific Publications,
13. Minto CF, Schnider TW, Gregg KM et al. (2003) Using the time of maximum effect-site concentration to combine pharmacokinetics and pharmacodynamics. Anesthesiology 99:324-333
14. Minto CF, Schnider TW, Egan TD et al. (1997) Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development. Anesthesiology 86:10-23
15. Roberts FL, Dixon J, Lewis GT et al. (1988) Induction and maintenance of propofol anaesthesia. A manual infusion scheme. Anaesthesia 43(5):14-17
16. Schuttler J, Schwilden H, Stoekel H (1983) Pharmacokinetics as applied to total intravenous anaesthesia. Practical implications. Anaesthesia 38(5):53-56
17. Shafer SL, Gregg KM (1992) Algorithms to rapidly achieve and maintain stable drug concentrations at the site of drug effect with a computer-controlled infusion pump. J Pharmacokinet Biopharm 20:147-169
18. Shafer SL, Siegel LC, Cooke JE, Scott JC (1998) Testing computer-controlled infusion pumps by simulation. Anesthesiology 68:261-266
19. Shafer SL, Stanski DR (1992) Improving the clinical utility of anesthetic drug pharmacokinetics. Anesthesiology 76:327-330
20. Shafer SL, Varvel JR, Gronert GA (1989) A comparison of parametric with semiparametric analysis of the concentration versus effect relationship of metocurine in dogs and pigs. J Pharm Biopharm 17:291-304
21. Shafer SL, Varvel JR (1991) Pharmacokinetics, pharmacodynamics, and rational opioid selection. Anesthesiology 74:53-63
22. Sheiner LB, Stanski DR, Vozeh S et al. (1979) Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. Clin Pharmacol Ther 25:358-371
23. Upton RN, Ludbrook GL (1997) A physiological model of the induction of anaesthesia with propofol in sheep. 1. Structure and estimation of parameters. Br J Anaesth 79:497-504
24. Varvel JR, Donoho DL, Shafer SL (1992) Measuring the predictive performance of computer-controlled infusion pumps. J Pharm Biopharm 20:63-94
25. Vuyk J, Engbers FH, Burm AG et al. (1995) Performance of computer-controlled infusion of propofol: an evaluation of five pharmacokinetic parameter sets. Anesthesia Analgesia 81:1275-1282
26. Wada DR, Drover DR, Lemmens HJ (1998) Determination of the distribution volume that can be used to calculate the intravenous loading dose. Clin Pharmacokinetics 35:1-7
27. Wakeling HG, Zimmerman JB, Howell S, Glass PS (1999) Targeting effect compartment or central compartment concentration of propofol: what predicts loss of consciousness? Anesthesiology 90:92-97
28. White M, Kenny GN (1990) Intravenous propofol anaesthesia using a computerized infusion system. Anaesthesia 45:204-209
29. Yasuda N, Lockhart SH, Eger EI et al. (1991) Comparison of kinetics of sevoflurane and isoflurane in humans. Anesth Analg 72:316-324
30. Youngs EJ, Shafer SL (1994) Pharmacokinetic parameters relevant to recovery from opioids. Anesthesiology 81:833-842