Impact of surgical trauma on human skeletal muscle protein synthesis

Clinical Science

Volumn 107, Issue 6, 2004, Pages 601-607

  Tjäder, Inga ^a   Essen, Pia ^a   Garlick, Peter J ^b   McNurlan, Margaret A ^b   Rooyackers, Olav ^a   Wernerman, Jan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Protein synthesis; Skeletal muscle; Stable isotope; Surgical trauma

Indexed keywords

MUSCLE PROTEIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN TISSUE; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; SKELETAL MUSCLE; SURGICAL INJURY;

ABDOMEN; ADULT; AGED; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCLE PROTEINS; MUSCLE, SKELETAL; PILOT PROJECTS; POSTOPERATIVE PERIOD; SURGICAL PROCEDURES, MINOR; SURGICAL PROCEDURES, OPERATIVE;

EID: 10344253784     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20040192     Document Type: Article

References (32)

1. Clague, M. B., Keir, M. J., Wright, P. D. and Johnston, I. D. (1983) The effects of nutrition and trauma on whole-body protein metabolism in man. Clin. Sci. 65, 165-175
2. Yamamori, H., Tashiro, T., Mashima, Y. and Okui, K. (1987) Effects of severity of surgical trauma on whole body protein turnover in patients receiving total parenteral nutrition. JPEN, J. Parenter. Enteral Nutr. 11, 454-457
3. Tashiro, T., Yamamori, H., Takagi, K., Morishima, Y. and Nakajima, N. (1996) Effect of severity of stress on whole-body protein kinetics in surgical patients receiving parenteral nutrition. Nutrition 12, 763-765
4. Tashiro, T., Yamamori, H., Takagi, K., Morishima, Y. and Nakajima, N. (1996) Increased contribution by myofibrillar protein to whole-body protein breakdown according to severity of surgical stress. Nutrition 12, 685-689
5. Cuthbertson, D. P., Fell, G. S., Smith, C. M. and Tilstone, W. J. (1972) Metabolism after injury. I. Effects of severity, nutrition, and environmental temperature on protein potassium, zinc, and creatine. Br. J. Surg. 59, 926-931
6. Essen, P., McNurlan, M. A., Wernerman, J., Vinnars, E. and Garlick, P. J. (1992) Uncomplicated surgery, but not general anesthesia, decreases muscle protein synthesis. Am. J. Physiol. 262, E253-E260
7. Essen, P., McNurlan, M. A., Sonnenfeld, T. et al. (1993) Muscle protein synthesis after operation: effects of intravenous nutrition. Eur. J. Surg. 159, 195-200
8. Thorell, A., Efendic, S., Gutniak, M., Haggmark, T. and Ljungqvist, O. (1993) Development of postoperative insulin resistance is associated with the magnitude of operation. Eur. J. Surg. 159, 593-599
9. Cruickshank, A. M., Fraser, W. D., Burns, H. J., Van Damme, J. and Shenkin, A. (1990) Response of serum interleukin-6 in patients undergoing elective surgery of varying severity. Clin. Sci. 79, 161-165
10. Bergstrom, J. (1962) Muscle electrolytes in man. Scand. J. Clin. Lab. Invest. 168, 11-13
11. McNurlan, M. A., Essen, P., Heys, S. D., Buchan, V., Garlick, P. J. and Wernerman, J. (1991) Measurement of protein synthesis in human skeletal muscle: further investigation of the flooding technique. Clin. Sci. 81, 557-564
12. Calder, A. G., Anderson, S. E., Grant, I., McNurlan, M. A. and Garlick, P. J. (1992) The determination of low d5-phenylalanine enrichment (0.002-0.09 atom percent excess), after conversion to phenylethylamine, in relation to protein turnover studies by gas chromatography/electron ionization mass spectrometry. Rapid Commun. Mass Spectrom. 6, 421-424
13. Essen, P., Thorell, A., McNurlan, M. A. et al. (1995) Laparoscopic cholecystectomy does not prevent the postoperative protein catabolic response in muscle. Ann. Surg. 222, 36-42
14. Blomqvist, B. I., Hammarqvist, F., von der Decken, A. and Wernerman, J. (1995) Glutamine and α-ketoglutarate prevent the decrease in muscle free glutamine concentration and influence protein synthesis after total hip replacement. Metab., Clin. Exp. 44, 1215-1222
15. Carli, F. and Halliday, D. (1996) Modulation of protein metabolism in the surgical patient. Effect of 48-hour continuous epidural block with local anesthetics on leucine kinetics. Reg. Anesth. 21, 430-435
16. Wernerman, J., Sylven, C., Jansson, E., von der Decken, A. and Vinnars, E. (1988) Enzymatic capacity and protein synthesis in human muscle postoperatively. Acta Chir. Scand. 154, 489-494
17. Schricker, T., Lattermann, R., Fiset, P., Wykes, L. and Carli, F. (2001) Integrated analysis of protein and glucose metabolism during surgery: effects of anesthesia. J. Appl. Physiol. 91, 2523-2530
18. 5]phenylalanine. Am. J. Physiol. 267, E102-E108
19. Hammarqvist, F., Wernerman, J., von der Decken, A. and Vinnars, E. (1986) The effect of branched chain amino acids (BCAA) on postoperative muscle protein synthesis and nitrogen balance. Clin. Nutr. 4, 68
20. Desai, S. P., Bistrian, B. R., Moldawer, L. L. and Blackburn, G. L. (1985) Whole-body nitrogen and tyrosine metabolism in surgical patients receiving branched-chain amino acid solutions. Arch. Surg. 120, 1345-1350
21. Rennie, M. J., Bennegard, K., Eden, E., Emery, P. W. and Lundholm, K. (1984) Urinary excretion and efflux from the leg of 3-methylhistidine before and after major surgical operation. Metab., Clin. Exp. 33, 250-256
22. O'Keefe, S. J., Moldawer, L. L., Young, V. R. and Blackburn, G. L. (1981) The influence of intravenous nutrition on protein dynamics following surgery. Metab., Clin. Exp. 30, 1150-1158
23. Petersson, B., Wernerman, J., Waller, S. O., von der Decken, A. and Vinnars, E. (1990) Elective abdominal surgery depresses muscle protein synthesis and increases subjective fatigue: effects lasting more than 30 days. Br. J. Surg. 77, 796-800
24. 14C]-leucine. Surgery 88, 294-300
25. Gamrin, L., Essen, P., Forsberg, A. M., Hultman, E. and Wernerman, J. (1996) A descriptive study of skeletal muscle metabolism in critically ill patients: free amino acids, energy-rich phosphates, protein, nucleic acids, fat, water, and electrolytes. Crit. Care Med. 24, 575-583
26. Tjäder, I., Rooyackers, O., Forsberg, A. M., Vesali, R. F., Garlick, P. J. and Wernerman, J. (2004) Effects on skeletal muscle of intravenous glutamine supplementation to ICU patients. Intens. Care Med. 30, 266-275
27. Tiao, G., Hobler, S., Wang, J. J. et al. (1997) Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle. J. Clin. Invest. 99, 163-168
28. Mansoor, O., Cayol, M., Gachon, P. et al. (1997) Albumin and fibrinogen syntheses increase while muscle protein synthesis decreases in head-injured patients. Am. J. Physiol. 273, E898-E902
29. Biolo, G., Fleming, R. Y., Maggi, S. P., Nguyen, T. T., Herndon, D. N. and Wolfe, R. R. (2002) Inverse regulation of protein turnover and amino acid transport in skeletal muscle of hypercatabolic patients. J. Clin. Endocrinol. Metab. 87, 3378-3384
30. Morrison, W. L., Gibson, J. N., Jung, R. T. and Rennie, M. J. (1988) Skeletal muscle and whole body protein turnover in thyroid disease. Eur. J. Clin. Invest. 18, 62-68
31. Rennie, M. J. and Harrison, R. (1984) Effects of injury, disease, and malnutrition on protein metabolism in man. Unanswered questions. Lancet i, 323-325
32. 3]-3-methylhistidine: a new method. Metab., Clin. Exp. 53, 1076-1080