Conversion from cyclosporine to tacrolimus after renal transplantation improves cardiovascular risk factors

International Immunopharmacology

Volumn 5, Issue 1, 2005, Pages 117-123

  Hohage, Helge ^a   Welling, U ^a   Heck, M ^a   Zeh, M ^a   Gerhardt, U ^b   Suwelack, B M ^b  

^a Nephrologisches Zentrum Emsland   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Cyclosporine; Drug conversion; Renal function; Renal transplantation; Tacrolimus

Indexed keywords

CREATININE; CYCLOSPORIN; DOXAZOSIN; ENALAPRIL; FUROSEMIDE; METOPROLOL; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; SIMVASTATIN; STEROID; TACROLIMUS;

ADULT; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY FUNCTION; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK REDUCTION; URIC ACID BLOOD LEVEL;

ADULT; CARDIOVASCULAR DISEASES; CHOLESTEROL; CREATININE; CYCLOSPORINE; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MYCOPHENOLIC ACID; PREDNISONE; RETROSPECTIVE STUDIES; RISK FACTORS; TACROLIMUS; URIC ACID;

EID: 10344248162     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2004.09.012     Document Type: Article

References (15)

1. F. Vincenti, S.C. Jensik, R.S. Filo, J. Miller, and J. Pirsch A long-term comparison of tacrolimus (FK506) and cyclosporine in kidney transplantation: evidence for improved allograft survival at five years Transplantation 73 2002 775 782
2. J.A. Kobashigawa, and B.L. Kasiske Hyperlipidemia in solid organ transplantation Transplantation 63 1997 331 338
3. K.M. Wissing, D. Abramowicz, N. Broeders, and P. Vereerstraeten Hypercholesterolemia is associated with increased kidney graft loss caused by chronic rejection in male patients with previous acute rejection Transplantation 70 2000 464 472
4. M. Köhnle, U. Zimmermann, P. Lutkes, K.H. Albrecht, T. Philipp, and U. Heemann Conversion from cyclosporine A to tacrolimus after kidney transplantation due to hyperlipidemia Transpl. Int. 13 Suppl. 1 2000 S345 S348
5. N. Selzner, F. Durand, J. Bernuau, M.A. Heneglan, J.S. Tuttle-Newhall, and J. Belghiti Conversion from cyclosporine to FK506 in adult liver transplant recipients: a combined North American and European experience Transplantation 72 2001 1061 1065
6. A.J. Matas, K.J. Gillingham, W.D. Payne, and J.S. Najarian The impact of an acute rejection episode on long-term renal allograft survival (t1/2) Transplantation 57 1994 857 859
7. W.E. Fitzsimmons, D. Thompson, S. Hariharan, and P. VanVeldhuisen Serum creatinine as a surrogate endpoint for graft loss in kidney transplantation: validation efforts from multicenter trials Am. J. Transplant. 2 Suppl. 3 2002 S272 [Abstract 533]
8. A.D. Mayer, J. Dmitrewski, J.P. Squifflet, T. Besse, B. Grabnesse, and B. Klein Multicenter randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of renal allograft rejection: a report of the European Tacrolimus Multicenter Renal Study Group Transplantation 64 1997 436 443
9. E.A. Burdmann, T.F. Andoh, L. Yu, and W.M. Bennett Cyclosporine nephrotoxicity Semin. Nephrol. 23 2003 465 476
10. A. Israni, S. Brozena, O. Pankewycz, R. Grossman, and R. Bloom Conversion to tacrolimus for the treatment of cyclosporine-associated nephrotoxicity in heart transplant recipients Am. J. Kidney Dis. 39 2002 E16
11. I.H. Klein, A. Abrahams, T. van Ede, R.J. Hené, H.A. Koomans, and G. Ligtenberg Different effects of tacrolimus and cyclosporine on renal hemodynamics and blood pressure in healthy subjects Transplantation 73 2002 732 736
12. J. Radermacher, M. Meiners, C. Bramlage, V. Kliem, M. Behrend, and H.J. Schlitt Pronounced renal vasoconstriction and systemic hypertension in renal transplant patients treated with cyclosporin A versus FK 506 Transpl. Int. 11 1998 3 10
13. R. Margreiter European Tacrolimus vs. Ciclosporin Microemulsion Renal Transplantation Study Group Efficacy and safety of tacrolimus compared with ciclosporin microemulsion in renal transplantation: a randomised multicentre study Lancet 359 2002 741 746
14. M.A. Artz, J.M. Boots, G. Ligtenberg, J.I. Roodnat, M.H. Christiaans, and P.F. Vos Improved cardiovascular risk profile and renal function in renal transplant patients after randomized conversion from cyclosporine to tacrolimus J. Am. Soc. Nephrol. 14 2003 1880 1888
15. M. Pascual, T. Theruvath, T. Kawai, N. Tolkoff-Rubin, and B.A. Cosimi Strategies to improve long-term outcomes after renal transplantation N. Engl. J. Med. 346 2002 580 590