Methotrexate bound to carbon particles used for treating cancers with lymph node metastases in animal experiments and a clinical pilot study

Cancer

Volumn 78, Issue 10, 1996, Pages 2199-2209

  Hagiwara, Akeo ^a   Takahashi, Toshio ^a   Sawai, Kiyoshi ^a   Sakakura, Chouhei ^a   Hoshima, Masakazu ^a   Ohyama, Takayuki ^a   Ohgaki, Masaharu ^a   Imanishi, Tsutomu ^a   Yamamoto, Akira ^b   Muranishi, Shozo ^b  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

activated carbon; chemotherapy; digestive cancer; drug delivery system; lymph node metastasis; methotrexate; P388 leukemia

Indexed keywords

ACTIVATED CARBON; METHOTREXATE;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MODEL; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; DIGESTIVE SYSTEM CANCER; DRUG ADSORPTION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; HUMAN; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

AGED; AGED, 80 AND OVER; ANIMALS; ANTINEOPLASTIC AGENTS; CARBON; DIGESTIVE SYSTEM NEOPLASMS; DOSAGE FORMS; HUMANS; LEUKEMIA P388; LYMPHATIC METASTASIS; MALE; METHOTREXATE; MICE; MICE, INBRED STRAINS; NEOPLASM TRANSPLANTATION; PILOT PROJECTS; RATS; RATS, INBRED STRAINS;

EID: 10344247624     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19961115)78:10<2199::AID-CNCR23>3.0.CO;2-T     Document Type: Article

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