Risk factors for delayed healing and recurrence of chronic venous leg ulcers - An analysis of 1324 legs

European Journal of Vascular and Endovascular Surgery

Volumn 29, Issue 1, 2005, Pages 74-77

  Gohel, M S ^a   Taylor, M ^a   Earnshaw, J J ^a   Heather, B P ^a   Poskitt, K R ^a   Whyman, Mark R ^a  

^a CHELTENHAM GENERAL HOSPITAL   (United Kingdom)

Author keywords

Colour venous duplex; Healing; Recurrence; Risk factor; Venous ulceration

Indexed keywords

ARTICLE; CHRONIC DISEASE; CHRONICITY; FEMALE; HUMAN; KAPLAN MEIER METHOD; LEG COMPRESSION; LEG ULCER; LIFE TABLE; MAJOR CLINICAL STUDY; MALE; NURSE PRACTITIONER; PRIORITY JOURNAL; RECURRENT DISEASE; REGRESSION ANALYSIS; RISK FACTOR; ULCER HEALING; VENOUS REFLUX; WOUND HEALING IMPAIRMENT;

AGE FACTORS; AGED; CHRONIC DISEASE; FEMALE; HUMANS; MALE; PREDICTIVE VALUE OF TESTS; RECURRENCE; RISK FACTORS; TIME FACTORS; ULTRASONOGRAPHY, DOPPLER, DUPLEX; VARICOSE ULCER; WOUND HEALING;

EID: 10244261658     PISSN: 10785884     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejvs.2004.10.002     Document Type: Article

References (26)

1. A. Adhikari M.H. Criqui V. Wooll J.O. Denenberg A. Fronek R.D. Langer M. Klauber The epidemiology of chronic venous diseases Phlebology 15 2000 2-18
2. O. Nelzen D. Bergqvist A. Lindhagen The prevalence of chronic lower-limb ulceration has been underestimated: Results of a validated population questionnaire Br J Surg 83 1996 255-258
3. P.D. Coleridge-Smith Venous ulcer Br J Surg 81 1994 1404-1405
4. A. Fletcher N. Cullum T.A. Sheldon A systematic review of compression treatment for venous leg ulcers Br Med J 315 1997 576-580
5. S.J. Palfreyman R. Lochiel J.A. Michaels A systematic review of compression therapy for venous leg ulcers Vasc Med 3 1998 301-313
6. C.E. Attinger E.J. Bulan Debridement. The key initial first step in wound healing Foot Ankle Clin 6 2001 627-660
7. R.F. Oien A. Hakansson B.U. Hansen M. Bjellerup Pinch skin grafting of chronic leg ulcers in primary care: Fourteen years experience Acta Derm Venereol 82 2002 275-278
8. R.F. Oien A. Hakannson Pinch skin transplantation for leg ulcers in primary care J Wound Care 9 2000 217-220
9. H. Puonti S. Asko-Seljavaara Excision and skin grafting of leg ulcers Ann Chir Gynaecol 87 1998 219-223
10. L.C. Argenta M.J. Morykwas Vacuum assisted closure: A new method for wound control and treatment: Clinical experience Ann Plast Surg 38 1997 563-576
11. M.P. Clare T.C. Fitzgibbons S.T. McMullen R.C. Stice C.F. Hayes L. Henkel Experience with the vacuum assisted closure negative pressure technique in the treatment of non-healing diabetic and dysvascular wounds Foot Ankle Int 23 2002 896-901
12. L. Krishnamoorthy K. Harding D. Griffiths K. Moore D. Leaper K. Poskitt R.G. Sibbald A. Brassard K. Dolynchuk J. Adams M. Whyman The clinical and histological effects of dermagraft in the healing of chronic venous leg ulcers Phlebology 18 2003 12-22
13. A.S. Ghauri I. Nyamekye A.J. Grabs J.R. Farndon M.R. Whyman K.R. Poskitt Influence of a specialised leg ulcer service and venous surgery on the outcome of venous leg ulcers Eur J Vasc Endovasc Surg 16 1998 238-244
14. E.L. Kaplan P. Meier Nonparametric estimation from incomplete observations J Am Stat Assoc 53 1958 458-481
15. J.R. Barwell A.S.K. Ghauri M. Taylor J. Deacon C. Wakely K.R. Poskitt M.R. Whyman Risk factors for the healing and recurrence of chronic venous leg ulcers Phlebology 15 2000 49-52
16. N. Perricone How to approach acute and chronic wound healing in the elderly Wounds 11 1999 145-151
17. B.K. Lal S. Saito P.J. Pappas F.T. Padberg Jr J.J. Cerveira R.W. Hobson W.N. Duran Altered proliferative response of dermal fibroblasts to TGF-Beta1 may contribute to chronic venous stasis ulcer J Vasc Surg 37 2003 1285-1293
18. M.V. Mendez J.D. Raffetto T. Phillips J.O. Menzoian H.Y. Park The proliferative capacity of neonatal skin fibroblasts is reduced after exposure to venous ulcer wound fluid: A potential mechanism for senescence in venous ulcers J Vasc Surg 30 1999 734-743
19. C. Seidman J.D. Raffetto B. Marian C. Croon C.C. Seah J.O. Menzoian bFGF-induced alterations in cellular markers of senescence in growth-rescued fibroblasts from chronic venous ulcer and venous reflux patients Ann Vasc Surg 17 2003 239-244
20. J.R. Barwell C.E. Davies J. Deacon J.J. Earnshaw J. Usher B.P. Heather D.C. Mitchell M. Taylor M.R. Whyman K.R. Poskitt Comparison of surgery and compression with compression alone in chronic venous ulceration (ESCHAR study): Randomised controlled trial Lancet 363 2004 1854-1859
21. S.G. Darke C. Penfold Venous ulceration and saphenous ligation Eur J Vasc Surg 6 1992 4-9
22. A.W. Bradbury C.V. Ruckley Foot volumetry can predict recurrent ulceration after subfascial ligation of perforators and saphenous ligation J Vasc Surg 18 1993 789-795
23. D.D. Wipke-Tevis N.A. Stotts Nutrition, tissue oxygenation, and healing of venous leg ulcers J Vasc Nurs 16 1998 48-56
24. J. Towler Cigarette smoking and its effects on wound healing J Wound Care 9 2000 100-104
25. A. Cole-King K.G. Harding Psychological factors and delayed healing in chronic wounds Psychosom Med 63 2001 216-220
26. F.P. Dix R. Brooke C.N. McCollum Venous disease is associated with an impaired range of ankle movement Eur J Vasc Endovasc Surg 25 2003 556-561