Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase with improved in vivo antiviral activity

Journal of Medicinal Chemistry

Volumn 39, Issue 21, 1996, Pages 4173-4180

  Moss, Neil ^a,b   Beaulieu, Pierre ^a   Duceppe, Jean Simon ^a   Ferland, Jean Marie ^a   Garneau, Michel ^a   Gauthier, Jean ^a   Ghiro, Elise ^a   Goulet, Sylvie ^a   Guse, Ingrid ^a   Jaramillo, Jorge ^a   Llinas Brunet, Montse ^a   Malenfant, Éric ^a   Plante, Raymond ^a   Poirier, Martin ^a   Soucy, Francois ^a   Wernic, Dominik ^a   Yoakim, Christiane ^a   Déziel, Robert ^a  

^a BOEHRINGER INGELHEIM CANADA LTD   (Canada)

^b BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; BILD 1263; BILD 1351; BILD 1357; ENZYME INHIBITOR; RIBONUCLEOTIDE REDUCTASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; HERPES SIMPLEX KERATITIS; HERPES SIMPLEX VIRUS; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; TOPICAL DRUG ADMINISTRATION;

ANIMALS; ANTIVIRAL AGENTS; CELLS, CULTURED; DIPEPTIDES; ENZYME INHIBITORS; KERATITIS, HERPETIC; MAGNETIC RESONANCE SPECTROSCOPY; MICE; OLIGOPEPTIDES; RIBONUCLEOTIDE REDUCTASES; SIMPLEXVIRUS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; UREA;

EID: 10244237616     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960324r     Document Type: Article

References (23)

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