Experience with a hospital-wide outbreak of vancomycin-resistant enterococci

American Journal of Infection Control

Volumn 24, Issue 5, 1996, Pages 372-379

  Quale, John ^a   Landman, David ^a   Atwood, Elaine ^a   Kreiswirth, Barry ^b   Willey, Barbara M ^c   Ditore, Virginia ^a   Zaman, Mohammed ^a   Patel, Keval ^a   Saurina, Guillermo ^a   Huang, Winnie ^a   Oydna, Elise ^a   Burney, Sibte ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INFECTION PREVENTION; INFECTION RATE; MAJOR CLINICAL STUDY; MORTALITY; STREPTOCOCCUS INFECTION;

EID: 10244236520     PISSN: 01966553     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-6553(96)90025-5     Document Type: Article

References (31)

1. CDC. Nosocomial enterococci resistant to vancomycin - United States, 1989-1993. MMWR 1993;42:597-9.
2. Lam S, Singer C, Tucci V, Morthland VH, Pfaller MA, Isenberg HD. The challenge of vancomycin-resistant enterococci: a. clinical and epidemiologic study. AJIC Am J Infect Control 1995;23:170-80.
3. Linden P, Pasculle AW, Kramer DJ, et al. Bacteremia with vancomycin-resistant Enterococcus faecium and vancomycin-sensitive Enterococcus faecium: comparison of epidemiology and clinical outcome [abstract 848]. In: Program and abstracts of the 33rd interscience conference on antimicrobial agents and chemotherapy, Washington D.C.: American Society for Microbiology 1993:275.
4. Karanfil LV, Murphy M, Josephson A, et al. A cluster of vancomycin-resistant Enterococcus faecium in an intensive care unit. Infect Control Hosp Epidemiol 1992;13:195-200.
5. Livornese LL, Dias S, Samel C, et al. Hospital-acquired infection with vancomycin-resistant E. faecium transmitted by electronic thermometers. Ann Intern Med 1992;117:112-6.
6. Handwerger S, Raucher B, Altarac D, et al. Nosocomial outbreak due to Enterococcus faecium highly resistant to vancomycin, penicillin, and gentamicin. Clin Infect Dis 1993;16:750-5.
7. Montecalvo MA, Horowitz H, Gedris C, et al. Outbreak of vancomycin-, ampicillin-, and aminoglycoside-resistant Enterococcus faecium bacteremia in an adult oncology unit. Antimicrob Agents Chemother 1994;38:1363-7.
8. Boyce JM, Opal SM, Chow JW, et al. Outbreak of multidrug-resistant Enterococcus faecium with transferable vanB class vancomycin resistance. J Clin Microbiol 1994;32:1148-53.
9. Boyce JM, Mermel LA, Zervos MJ, et al. Effective measures for controlling vancomycin-resistant E. faecium [abstract J149]. In: Program and abstracts of the 34th interscience conference on antimicrobial agents and chemotherapy, Washington, D.C.: American Society for Microbiology, 1994:144.
10. Landman D, Mobarakai NK, Quale JM. Novel antibiotic regimens against Enterococcus faecium resistant to ampicillin, vancomycin, and gentamicin. Antimicrob Agents Chemother 1993;37:1904-8.
11. Facklam RR, Collins MD. Identification of Enterococcus species isolated from human infections by a conventional test scheme. J Clin Microbiol 1989;27:731-4.
12. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7A3;13(25). Villanova, Pa.: National Committee for Clinical Laboratory Standards, 1993.
13. Frieden TR, Munsiff SS, Low DE, et al. Emergence of vancomycin-resistant enterococci in New York City. Lancet 1993;342:76-9.
14. Murray BE, Singh KV, Heath D, Sharme BR, Weinstock GM. Comparison of genomic DNAs of different enterococcal isolates using restriction endonucleases with infrequent recognition sites. J Clin Microbiol 1990;28:2059-63.
15. Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: Criteria for bacterial strain typing. J Clin Microbiol 1995;33:2233-9.
16. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections, 1988. AJIC Am J Infect Control 1988;16:128-40.
17. Landman D, Quale JM, Oydna E, et al. Comparison of five selective media for identifying fecal carriage of vancomycin-resistant enterococci. J Clin Microbiol 1996;34:751-2.
18. Nichols RL, Muzik AC. Enterococcal infections in surgical patients: the mystery continues. Clin Infect Dis 1992;15:72-6.
19. Willey SH, Hindes RG, Eliopoulos GM, Moellering RC Jr. Effects of clindamycin and gentamicin and other antimicrobial combinations against enterococci in an experimental model of intra-abdominal abscess. Surg Gynecol Obstet 1989;169:199-202.
20. Horvitz AA, VonGraevenitz A. A clinical study of the role of enterococci as sole agents of wound and tissue infection. Yale J Biol Med 1977;50:391-5.
21. Landman D, Quale JM, Mobarakai NK, Zaman MM. Ampicillin plus ciprofloxacin therapy of experimental endocarditis caused by multidrug resistant Enterococcus faecium. J Antimicrob Chemother 1995;36:253-8.
22. Jordens JZ, Bates J, Griffiths DT. Faecal carriage and nosocomial spread of vancomycin-resistant Enterococcus faecium. J Antimicrob Chemother 1994;34:515-28.
23. Uttley AHC, Collins CH, Naidoo J, George RC. Vancomycin-resistant enterococci [Letter]. Lancet 1988;1:57-8.
24. Hospital Infection Control Practices Advisory Committee. Recommendations for preventing the spread of vancomycin resistance: recommendations of the Hospital Infection Control Practices Advisory Committee. AJIC Am J Infect Control 1995;15:105-13.
25. Boyle JF, Soumakis SA, Rendo A, et al. Epidemiologic analysis and genotypic characterization of a nosocomial outbreak of vancomycin resistant enterococci. J Clin Microbiol 1993;31:1280-5.
26. Edmond MB, Ober JF, Weinbaum DL et al. Vancomycin-resistant Enterococcus faecium bacteremia: risk factors for infection. Clin Infect Dis 1995;20:1126-33.
27. Morris Jr JG, Shay DK, Hebden JN, et al. Enterococci resistant to multiple antimicrobial agents, including vancomycin: establishment of endemicity in a university medical center. Ann Intern Med 1995;123:250-9.
28. Wells CL, Juni BA, Cameron SB, et al. Stool carriage, clinical isolation, and mortality during an outbreak of vancomycin-resistant enterococci in hospitalized medical and/or surgical patients. Clin Infect Dis 1995;21:45-50.
29. Quale J, Patel K, Zaman M, et al. Fecal carriage of vancomycin resistant enterococci in nursing home and hospitalized patients [abstract 79]. Clin Infect Dis 1995;21:733.
30. Linden P, Pasculle AW, Kramer DJ, Kusne S, Manez R. The duration of fecal carriage of vancomycin-resistant Enterococcus faecium. [abstract J150]. In: Program and abstracts of the 34th interscience conference on antimicrobial agents and chemotherapy, Washington, D.C.: American Society for Microbiology, 1994:144.
31. Montecalvo MA, Carraher P, Gedris C, Van Horn K, Wormser GP. Persistence of perianal colonization with vancomycin-resistant enterococci in adult oncology patients [abstract J152]. In: Program and abstracts of the 34th interscience conference on antimicrobial agents and chemotherapy, Washington, D.C.: American Society for Microbiology, 1994:145.