Tolerance, pharmacokinetics and efficacy of once daily amikacin for treatment of Pseudomonas aeruginosa pulmonary exacerbations in cystic fibrosis patients

European Journal of Pediatrics

Volumn 155, Issue 11, 1996, Pages 948-953

  Vic, P ^a   Ategbo, S ^a   Turck, D ^a   Husson, M O ^a   Tassin, E ^a   Loeuille, G A ^b   Deschildre, A ^a   Druon, D ^b   Elian, J C ^b   Arrouet Lagandre, C ^a   Farriaux, J P ^a  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b City Hospital   (France)

Author keywords

Aminoglycosides; Child; Cystic fibrosis; Once daily antibiotics; Pseudmononas aeruginosa

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; CEFTAZIDIME; IMIPENEM;

ARTICLE; CLINICAL ARTICLE; CYSTIC FIBROSIS; DRUG EFFICACY; DRUG TOLERANCE; FEMALE; GRAM NEGATIVE INFECTION; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; PHARMACOKINETICS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SCHOOL CHILD;

EID: 10244232857     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02282885     Document Type: Article

References (17)

1. Allen MB, Mellon AF, Simmonds EJ, Page RL, Littlewood JM (1993) Changes in nocturnal oximetry after treatment of exacerbations in cystic fibrosis. Arch Dis Child 69 : 197-201
2. Autret E, Marchand S, Breteau M, Grenier B (1986) Pharmacokinetics of amikacin in cystic fibrosis: a study of bronchial diffusion. Eur J Clin Pharmacol 31 : 79-83
3. Braggion C, Pradal U, Mastella G (1992) Hemoglobin desaturation during sleep and daytime in patients with cystic fibrosis and severe airway obstruction. Acta Pædiatr 81 : 1002-1006
4. Byl B, Baran D, Herchuelz A, Roucloux I, Lambert C, Van der Auwera P, Thys JP (1992) Sputum penetration of a single daily dose of amikacin and a continuous infusion of ceftazidime in cystic fibrosis patients. 32nd ICAAC (Anaheim); Abstract 209
5. Gilbert DN (1991) Once-daily aminoglycoside therapy. Antimicrob Agents Chemother 35 : 399-405
6. Gnansounou M, Nelken B, Vic P, Husson MO, Mazingue F, Lambilliotte A, Farriaux JP (1995) Pharmacokinetics of once-daily teicoplanin, amikacin, ceftriaxone and continuous infusion of vancomycin, ceftazidime plus once-daily amikacin in febrile neutropenic children. International Society of Paediatric Oncology. XXVIIth meeting, Montevideo, October 10-14. Med Pediatr Oncol 4 : 288 (abstract P-38)
7. Levy J, Baran D, Klastersky J (1982) Comparative study of the anti-bacterial activity of amikacin and tobramycin during Pseudomonas pulmonary infection in patients with cystic fibrosis. J Antimicrob Chemother 10 : 227-234
8. Moore RD, Lietman PS, Smith CR (1987) Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration. J Infect Dis 155 : 93-99
9. Neijens HJ (1989) Strategies and perspectives in treatment of respiratory infections. Acta Pædiatr Scand [Suppl] 363:66-73
10. Nelson J (1985) Management of acute pulmonary exacerbations in cystic fibrosis: a critical appraisal. J Pediatr 106:1030-1033
11. Nilsson L, Sören L, Rädberg G (1987) Frequencies of variants resistant to different aminoglycosides in Pseudomonas aeruginosa. J Antimicrob Chemother 20:255-259
12. Prandota J (1987) Drug disposition in cystic fibrosis: progress in understanding pathophysiology and pharmacokinetics. Pediatr Infect Dis 6:1111-1126
13. Sempé M, Pedron G, Roy-Pernot MF (1979) Auxologie. Méthodes et séquences. Théraplix
14. Smith AL (1986) Antibiotic therapy in cystic fibrosis: evaluation of clinical trials. J Pediatr 108:866-870
15. Smith AL, Ramsey B, Redding G, Haas J (1989) Endobronchial infection in cystic fibrosis. Acta Paediatr Scand [Suppl] 363:31-36
16. Szaff M, Hoiby N, Flensborg W (1983) Frequent antibiotic therapy improves survival of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection. Acta Paediatr Scand 72:651-657
17. Van der Auwera P (1991) Pharmacokinetic evaluation of single daily dose amikacin. J Antimicrob Chemother 27 [Suppl C]:63-71