Optimization of electroporation waveforms for cell sterilization

IEEE Transactions on Industry Applications

Volumn 40, Issue 6, 2004, Pages 1489-1497

  Jayaram, Shesha H ^a   Boggs, Steven A ^b,c  

^a UNIVERSITY OF WATERLOO   (Canada)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cell membrane; Electroporation; Pulsed power; Sterilization; Transient finite element analysis

Indexed keywords

APPROXIMATION THEORY; ELECTRIC FIELD EFFECTS; ELECTROLYTES; FINITE ELEMENT METHOD; MATHEMATICAL MODELS; NUMERICAL METHODS; OPTIMIZATION; PERMITTIVITY; STERILIZATION (CLEANING); WAVEFORM ANALYSIS;

CELL STERILIZATION; CYTOPLASM; ELECTROPORATION; PULSED POWER; TRANSIENT FINITE ELEMENT ANALYSIS;

CELL MEMBRANES;

EID: 10244221037     PISSN: 00939994     EISSN: None     Source Type: Journal    
DOI: 10.1109/TIA.2004.836134     Document Type: Article

References (19)

1. E. Neumann, A. E. Sowers, and C. A. Jordan, Eds., Electroporation and Electrofusion in Cell Biology. New York: Plenum, 1989.
2. T. Heida, J. B. M. Wagenaar, W. L. C. Rutten, and E. Marani, "Investigating membrane breakdown of neuronal cells exposed to nonunion electric fields by finite-element modeling and experiments," IEEE Trans. Biomed. Eng., vol. 49, pp. 1195-1203, Oct. 2002.
3. T. Y. Tsong, "Review on electroporation of cell membranes and some related phenomena," Bioelectrochem. Bioenergetics, vol. 24, pp. 271-295, 1990.
4. S. Jayaram, "Sterilization of liquid foods by pulsed electric fields," IEEE Elect. Insul. Mag., vol. 16, pp. 17-25, Nov. /Dec. 2000.
5. S. Katsuki, K. Moreira, F. Dobbs, R. P. Joshi, and K. H. Schoenbach, "Bacterial decontamination with nanosecond pulsed electric fields," in Conf. Rec. 2002 Twenty-Fifth Int. High-Voltage Workshop/2002 Power Modulator Symp., 2002, pp. 648-651.
6. K. H. Schoenbach, S. Katsuki, R. H. Stark, E. S. Buescher, and S. J. Beebe, "Bioelectrics-new applications for pulsed power technology," IEEE Trans. Plasma Sci., vol. 30, pp. 293-300, Feb. 2002.
7. S. J. Beebe, L. J. Rec, P. M. Fox, R. H. Stark, K. Somers, and K. H. Schoenbach, "Nanosecond pulsed electric field effects on cells and tissues: Apoptosis induction and tumor growth inhibition," IEEE Trans. Plasma Sci., vol. 30, pp. 286-292, Feb. 2002.
8. D. C. Chang, "Cell poration and cell fusion using an oscillating electric field," Biophys. J., vol. 56, pp. 641-652, 1989.
9. B.-L. Qin, Q. Zhang, G. V. Barbosa-Canovas, B. G. Swanson, and P. D. Pedrow, "Inactivation of microorganizms by pulsed electric fields of different voltage waveforms," IEEE Trans. Dielect. Elect. Insul., vol. 1, pp. 1047-1057, Dec. 1994.
10. S. Y. Ho, G. S. Mittal, J. D. Cross, and M. W. Griffiths, " Inactivation of pseudomonas fluorescens by HV electric pulses," J. Food Sci., vol. 60, no. 6, pp. 1337-1343, 1995.
11. S. A. Freeman, M. A. Wang, and J. C. Weaver, "Theory of electroporation of planar bilayer membranes: predictions of the aqueous area, change in capacitance, and pore-pore separation," Biophys. J., vol. 67, pp. 42-56, 1994.
12. A. Abou-Ghazala and K. H. Schoenbach, "Biofouling prevention with pulsed electric fields," IEEE Trans. Plasma Sci., vol. 28, pp. 115-121, Feb. 2000.
13. P. Love, "Correlation of Fourier transforms of pulsed electric field waveform and microorganisms inactivation," IEEE Trans. Dielect. Elect. Insul., vol. 5, pp. 142-147, Feb. 1998.
14. M. Winterhalter, K.-H. Klotz, R. Benz, and M. Arnold, "On the dynamics of the electric field induced breakdown in lipid membranes," IEEE Trans. Ind. Applicat., vol. 32, pp. 125-130, Jan./Feb. 1996.
15. J. Kuang, J. D. Lavers, and S. A. Boggs, "Program for transient nonlinear finite element analysis with applications to coupled field problems," in Proc. 1997 Int. Symp. High Voltage Engineering, vol. 6, Montreal, QC, Canada, pp. 141-144.
16. Z. Zheng and S. A. Boggs, "Efficient solution to transient nonlinear field problems," in 2002 Annu. Rep. IEEE Conf. Electrical Insulation and Dielectric Phenomena, Oct. 2002, pp. 130-133.
17. S. A. Boggs and J. Kuang, "High field effects in solid dielectrics," IEEE Elect. Insul. Mag., vol. 14, pp. 5-12, Nov./Dec. 1998.
18. S. A. Boggs and J. Y. Zhou, "Dielectric property measurement of nonlinear grading materials," in 2000 Annu. Rep. IEEE Conf. Electrical Insulation and Dielectric Phenomena, pp. 764-767.
19. J. Y. Zhou and S. A. Boggs, "Measurement of nonlinear dielectric properties - Effect of dielectric dispersion," in 2001 Annu. Rep. IEEE Conf. Electrical Insulation and Dielectric Phenomena, pp. 153-156.