Prevention of hyperacute rejection by human decay accelerating factor in xenogeneic perfused working hearts

Transplantation

Volumn 62, Issue 6, 1996, Pages 729-734

  Schmoeckel, Michael ^a   Nollert, Georg ^b   Shahmohammadi, Mehdi ^b   Young, Vincent K ^c   Chavez, Gilda ^c   Kasper König, Walter ^c   White, David J G ^c   Müller Höcker, Josef ^b   Arendt, Rainer M ^b   Wilbert Lampen, Ute ^b   Hammer, Claus ^b   Reichart, Bruno ^b  

^a Douglas House ^*  (United Kingdom)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; CREATINE KINASE; DECAY ACCELERATING FACTOR; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MONOCLONAL ANTIBODY; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; CELL DAMAGE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; GRAFT REJECTION; HEART PERFUSION; HEART TRANSPLANTATION; HEMODYNAMIC PARAMETERS; HISTOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; SWINE; TRANSGENIC ANIMAL; XENOTRANSPLANTATION;

EID: 10144256486     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199609270-00005     Document Type: Article

References (16)

1. Battistini B, D'Orleans-Juste P, Sirois P. Endothelins: circulating plasma levels and presence in other biologic fluids. Lab Invest 1993; 68: 600.
2. Butler J, Rocker GM, Westaby S. Inflammatory response to cardiopulmonary bypass. Ann Thorac Surg 1993; 55: 552.
3. Goldberg L, Lee J, Cairns T, et al. Inhibition of the human antipig xenograft reaction with soluble oligosaccharides. Transplant Proc 1995; 27: 249.
4. Langford GA, Yannoutsos N, Cozzi E, et al. Production of pigs transgenic for human decay accelerating factor. Transplant Proc 1994; 26: 1400.
5. Leventhal JR, John R, Fryer JP, Witson JC, et al. Removal of baboon and human antiporcine IgG and IgM natural antibodies by immunoadsorption. Transplantation 1995; 59: 294.
6. Lu CY, Khair-El-Din TA, Dawidson IA, et al. Xenotransplantation. FASEB J 1994; 8: 1122.
7. Markmann JF, Barker CF. Basic and clinical considerations in the use of xenografts. Curr Probl Surg 1994; 31: 390.
8. Pang LM, Stalcup SA, Lipset JS, et al. Increased circulating bradykinin during hypothermia and cardiopulmonary bypass in children. Circulation 1979; 60: 1503.
9. Platt JL, Fischel RJ, Matas AJ, Reif SA, Bolman RM, Bach FH. Immunopathology of hyperacute xenograft rejection in a swine-to-primate model. Transplantation 1991; 52: 214.
10. Robbins RC, Mitchell ME, Sachs DH, Clark RE. Human plasma causes rapid dysfunction in ex vivo pig hearts. J Heart Lung Transplant 1994; 13: 877.
11. Rosengard AM, Cary N, Horsley J, et al. Endothelial expression of human decay accelerating factor in transgenic pig tissue: a potential approach for human complement inactivation in discordant xenografts. Transplant Proc 1995; 27: 326.
12. Rubanyi GM, Parker Botelho LH. Endothelins. FASEB J 1991; 5: 2713.
13. Saadi S, Ihrcke NS, Platt JL. Endothelial cell shape and hyperacute rejection. Transplant Proc 1994; 26: 1149.
14. Strahan KM, Gu F, Andersson L, Gustafsson K. Pig a1 3galactosyltransferase: sequence of a full-length cDNA clone, chromosomal localisation of the corresponding gene, and inhibition of expression in cultured pig endothelial cells. Transplant Proc 1995; 27: 245.
15. Suckfüll M, Müdsam M, Pieske O, Enders G, Babic R, Hammer C. Immunohistological studies of complement activation after xenogeneic perfusion of a working heart model. Transplant Int 1984; 7: 324.
16. Suckfüll MM, Pieske O, Müdsam M, Babic R, Hammer C. The contribution of endothelial cells to hyperacute rejection in xenogeneic perfused working hearts. Transplantation 1994; 57: 262.